Trade Names: | |
Synonyms: | |
Status: | Approved (1984) |
Entry Type: | Small molecule |
Molecule Category: | Salt |
UNII: | B025Y34C54 |
Parent Compound: | ACEBUTOLOL |
InChI Key | KTUFKADDDORSSI-UHFFFAOYSA-N |
---|---|
Smile | |
InChI |
|
Property Name | Value |
---|---|
Molecular Formula | C18H29ClN2O4 |
Molecular Weight | 372.89 |
AlogP | 2.37 |
Hydrogen Bond Acceptor | 5.0 |
Hydrogen Bond Donor | 3.0 |
Number of Rotational Bond | 10.0 |
Polar Surface Area | 87.66 |
Molecular species | BASE |
Aromatic Rings | 1.0 |
Heavy Atoms | 24.0 |
Action | Mechanism of Action | Reference |
---|---|---|
ANTAGONIST | Beta-1 adrenergic receptor antagonist | DailyMed |
Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
---|---|---|---|---|---|---|
Transporter
Electrochemical transporter
SLC superfamily of solute carriers
SLC21/SLCO family of organic anion transporting polypeptides
|
- | - | - | - | 74 |
Resources | Reference |
---|---|
ChEBI | 2380 |
ChEMBL | CHEMBL1200813 |
EPA CompTox | DTXSID5045461 |
FDA SRS | B025Y34C54 |
Guide to Pharmacology | 7107 |
KEGG | C07677 |
PubChem | 36816 |
SureChEMBL | SCHEMBL41004 |
ZINC | ZINC00968255 |