DrugMapper


Display Options: Drug type Therapeutic Area Route of administration Mechanism of Action Indication Status		Total: 28


Small molecule Approved CANCER; MUSCULOSKELETAL; OTHER; PREGNANCY AND GYNECOLOGY INJECTION; ORAL; TOPICAL; VAGINAL Memory; Reperfusion Injury; Brain Injuries; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Shock; Urinary Bladder, Overactive; Alzheimer Disease; Angina, Unstable; Anorexia Nervosa; Bone Diseases; Bone Diseases, Metabolic; Cardiovascular Diseases; Colonic Neoplasms; Coronary Disease; Cystitis, Interstitial; Diabetes Mellitus; Endometrial Neoplasms; Heart Diseases; Hot Flashes; Hypercholesterolemia; Hypertension; Lupus Erythematosus, Systemic; Memory Disorders; Myocardial Infarction; Myocardial Ischemia; Stroke; Thrombosis; Turner Syndrome; Atrophic Vaginitis; Atrophy; Breast Neoplasms; Dyspareunia; Hypogonadism; Menopause; Osteoporosis; Osteoporosis, Postmenopausal; Primary Ovarian Insufficiency Estrogen receptor agonist

Small molecule

Approved

CANCER; MUSCULOSKELETAL; OTHER; PREGNANCY AND GYNECOLOGY

INJECTION; ORAL; TOPICAL; VAGINAL

Memory; Reperfusion Injury; Brain Injuries; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Shock; Urinary Bladder, Overactive; Alzheimer Disease; Angina, Unstable; Anorexia Nervosa; Bone Diseases; Bone Diseases, Metabolic; Cardiovascular Diseases; Colonic Neoplasms; Coronary Disease; Cystitis, Interstitial; Diabetes Mellitus; Endometrial Neoplasms; Heart Diseases; Hot Flashes; Hypercholesterolemia; Hypertension; Lupus Erythematosus, Systemic; Memory Disorders; Myocardial Infarction; Myocardial Ischemia; Stroke; Thrombosis; Turner Syndrome; Atrophic Vaginitis; Atrophy; Breast Neoplasms; Dyspareunia; Hypogonadism; Menopause; Osteoporosis; Osteoporosis, Postmenopausal; Primary Ovarian Insufficiency

Estrogen receptor agonist


Small molecule Approved MUSCULOSKELETAL; OTHER ORAL Anemia, Diamond-Blackfan; Canavan Disease; Diabetes Mellitus, Type 2; Esophageal Stenosis; Fanconi Anemia; Frontotemporal Dementia; Gangliosidoses; Gaucher Disease; Glucose Intolerance; Hematologic Diseases; Lymphoma, Primary Effusion; Respiratory Syncytial Virus Infections; Status Asthmaticus; Acquired Immunodeficiency Syndrome; Adrenal Insufficiency; AIDS-Associated Nephropathy; Amyotrophic Lateral Sclerosis; Anemia, Hemolytic, Autoimmune; Autoimmune Diseases; Bell Palsy; Blast Crisis; Blastic Plasmacytoid Dendritic Cell Neoplasm; Burkitt Lymphoma; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Castleman Disease; Chemical and Drug Induced Liver Injury; Churg-Strauss Syndrome; Embolism, Cholesterol; Gastrointestinal Stromal Tumors; Geographic Atrophy; Glomerulosclerosis, Focal Segmental; Graves Ophthalmopathy; Hearing Loss; Hearing Loss, Sensorineural; Hemangioma; Hematologic Neoplasms; Hemophilia A; Hepatitis, Alcoholic; Hepatitis, Autoimmune; Hepatitis C; HIV Infections; Hypersensitivity; IgA Vasculitis; Immunoblastic Lymphadenopathy; Immunoglobulin G4-Related Disease; Kidney Neoplasms; Lichen Planus, Oral; Lung Diseases; Lung Neoplasms; Lymphohistiocytosis, Hemophagocytic; Lymphoma, AIDS-Related; Lymphoma, B-Cell; Lymphoma, Large-Cell, Anaplastic; Lymphoma, T-Cell; Lymphoproliferative Disorders; Melanoma; Multiple Sclerosis, Relapsing-Remitting; Myelodysplastic Syndromes; Myeloproliferative Disorders; Nephritis, Interstitial; Neuromyelitis Optica; Opsoclonus-Myoclonus Syndrome; Pneumonia, Viral; Polycythemia Vera; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating; Premature Birth; Primary Myelofibrosis; Pulmonary Fibrosis; Stiff-Person Syndrome; Takayasu Arteritis; Thrombocythemia, Essential; Thymus Neoplasms; Vestibular Neuronitis; Alzheimer Disease; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Breast Neoplasms; Bronchiolitis Obliterans Syndrome; Cardiomyopathies; Central Nervous System Neoplasms; Cystic Fibrosis; Deafness; Giant Cell Arteritis; Glomerulonephritis, IGA; Glomerulonephritis, Membranous; Graft vs Host Disease; Granulomatosis with Polyangiitis; Heart Diseases; Heart Failure; Histiocytosis, Langerhans-Cell; Hodgkin Disease; Hypereosinophilic Syndrome; Idiopathic Pulmonary Fibrosis; Kidney Diseases; Kidney Failure, Chronic; Leukemia, Biphenotypic, Acute; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Lymphoid; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Myeloid, Acute; Lupus Nephritis; Lymphoma, B-Cell, Marginal Zone; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Peripheral; Microscopic Polyangiitis; Multiple Myeloma; Muscular Dystrophy, Duchenne; Myasthenia Gravis; Nasal Polyps; Neoplasms, Plasma Cell; Neuroblastoma; Pain; Pemphigoid, Bullous; Pericarditis; Polymyalgia Rheumatica; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Pulmonary Disease, Chronic Obstructive; Purpura, Thrombotic Thrombocytopenic; Renal Insufficiency, Chronic; Retroperitoneal Fibrosis; Rhinitis, Allergic, Perennial; Sarcoidosis, Pulmonary; Sarcoma; Sciatica; Severe Acute Respiratory Syndrome; Sinusitis; Tuberculosis; Urticaria; Uveitis; Uveitis, Intermediate; Vasculitis; Waldenstrom Macroglobulinemia; Addison Disease; Adrenal Hyperplasia, Congenital; Anemia; Anemia, Aplastic; Anemia, Hemolytic; Arthritis; Arthritis, Gouty; Arthritis, Juvenile; Arthritis, Psoriatic; Arthritis, Rheumatoid; Asthma; Berylliosis; Brain Neoplasms; Bursitis; Chorioretinitis; Choroiditis; Colitis, Ulcerative; Conjunctivitis, Allergic; Crohn Disease; Dermatitis, Atopic; Dermatitis, Contact; Dermatitis, Exfoliative; Dermatitis Herpetiformis; Dermatitis, Seborrheic; Dermatomyositis; Endocrine System Diseases; Erythema Multiforme; Herpes Zoster Ophthalmicus; Hypercalcemia; Inflammation; Iridocyclitis; Iritis; Keratitis; Leukemia; Lupus Erythematosus, Systemic; Lymphoma; Multiple Sclerosis; Mycosis Fungoides; Myocarditis; Neoplasms; Nephrotic Syndrome; Ophthalmia, Sympathetic; Optic Neuritis; Osteoarthritis; Pemphigus; Peptic Ulcer; Pneumonia; Polymyositis; Psoriasis; Pulmonary Eosinophilia; Purpura, Thrombocytopenic, Idiopathic; Rhinitis, Allergic; Rhinitis, Allergic, Seasonal; Sarcoidosis; Serum Sickness; Spondylitis; Spondylitis, Ankylosing; Stevens-Johnson Syndrome; Synovitis; Tennis Elbow; Tenosynovitis; Thrombocytopenia; Thyroiditis, Subacute; Trichinellosis; Tuberculosis, Meningeal; Tuberculosis, Pulmonary; Uveitis, Posterior Glucocorticoid receptor agonist

Small molecule

Approved

MUSCULOSKELETAL; OTHER

ORAL

Anemia, Diamond-Blackfan; Canavan Disease; Diabetes Mellitus, Type 2; Esophageal Stenosis; Fanconi Anemia; Frontotemporal Dementia; Gangliosidoses; Gaucher Disease; Glucose Intolerance; Hematologic Diseases; Lymphoma, Primary Effusion; Respiratory Syncytial Virus Infections; Status Asthmaticus; Acquired Immunodeficiency Syndrome; Adrenal Insufficiency; AIDS-Associated Nephropathy; Amyotrophic Lateral Sclerosis; Anemia, Hemolytic, Autoimmune; Autoimmune Diseases; Bell Palsy; Blast Crisis; Blastic Plasmacytoid Dendritic Cell Neoplasm; Burkitt Lymphoma; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Castleman Disease; Chemical and Drug Induced Liver Injury; Churg-Strauss Syndrome; Embolism, Cholesterol; Gastrointestinal Stromal Tumors; Geographic Atrophy; Glomerulosclerosis, Focal Segmental; Graves Ophthalmopathy; Hearing Loss; Hearing Loss, Sensorineural; Hemangioma; Hematologic Neoplasms; Hemophilia A; Hepatitis, Alcoholic; Hepatitis, Autoimmune; Hepatitis C; HIV Infections; Hypersensitivity; IgA Vasculitis; Immunoblastic Lymphadenopathy; Immunoglobulin G4-Related Disease; Kidney Neoplasms; Lichen Planus, Oral; Lung Diseases; Lung Neoplasms; Lymphohistiocytosis, Hemophagocytic; Lymphoma, AIDS-Related; Lymphoma, B-Cell; Lymphoma, Large-Cell, Anaplastic; Lymphoma, T-Cell; Lymphoproliferative Disorders; Melanoma; Multiple Sclerosis, Relapsing-Remitting; Myelodysplastic Syndromes; Myeloproliferative Disorders; Nephritis, Interstitial; Neuromyelitis Optica; Opsoclonus-Myoclonus Syndrome; Pneumonia, Viral; Polycythemia Vera; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating; Premature Birth; Primary Myelofibrosis; Pulmonary Fibrosis; Stiff-Person Syndrome; Takayasu Arteritis; Thrombocythemia, Essential; Thymus Neoplasms; Vestibular Neuronitis; Alzheimer Disease; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Breast Neoplasms; Bronchiolitis Obliterans Syndrome; Cardiomyopathies; Central Nervous System Neoplasms; Cystic Fibrosis; Deafness; Giant Cell Arteritis; Glomerulonephritis, IGA; Glomerulonephritis, Membranous; Graft vs Host Disease; Granulomatosis with Polyangiitis; Heart Diseases; Heart Failure; Histiocytosis, Langerhans-Cell; Hodgkin Disease; Hypereosinophilic Syndrome; Idiopathic Pulmonary Fibrosis; Kidney Diseases; Kidney Failure, Chronic; Leukemia, Biphenotypic, Acute; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Lymphoid; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Myeloid, Acute; Lupus Nephritis; Lymphoma, B-Cell, Marginal Zone; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Peripheral; Microscopic Polyangiitis; Multiple Myeloma; Muscular Dystrophy, Duchenne; Myasthenia Gravis; Nasal Polyps; Neoplasms, Plasma Cell; Neuroblastoma; Pain; Pemphigoid, Bullous; Pericarditis; Polymyalgia Rheumatica; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Pulmonary Disease, Chronic Obstructive; Purpura, Thrombotic Thrombocytopenic; Renal Insufficiency, Chronic; Retroperitoneal Fibrosis; Rhinitis, Allergic, Perennial; Sarcoidosis, Pulmonary; Sarcoma; Sciatica; Severe Acute Respiratory Syndrome; Sinusitis; Tuberculosis; Urticaria; Uveitis; Uveitis, Intermediate; Vasculitis; Waldenstrom Macroglobulinemia; Addison Disease; Adrenal Hyperplasia, Congenital; Anemia; Anemia, Aplastic; Anemia, Hemolytic; Arthritis; Arthritis, Gouty; Arthritis, Juvenile; Arthritis, Psoriatic; Arthritis, Rheumatoid; Asthma; Berylliosis; Brain Neoplasms; Bursitis; Chorioretinitis; Choroiditis; Colitis, Ulcerative; Conjunctivitis, Allergic; Crohn Disease; Dermatitis, Atopic; Dermatitis, Contact; Dermatitis, Exfoliative; Dermatitis Herpetiformis; Dermatitis, Seborrheic; Dermatomyositis; Endocrine System Diseases; Erythema Multiforme; Herpes Zoster Ophthalmicus; Hypercalcemia; Inflammation; Iridocyclitis; Iritis; Keratitis; Leukemia; Lupus Erythematosus, Systemic; Lymphoma; Multiple Sclerosis; Mycosis Fungoides; Myocarditis; Neoplasms; Nephrotic Syndrome; Ophthalmia, Sympathetic; Optic Neuritis; Osteoarthritis; Pemphigus; Peptic Ulcer; Pneumonia; Polymyositis; Psoriasis; Pulmonary Eosinophilia; Purpura, Thrombocytopenic, Idiopathic; Rhinitis, Allergic; Rhinitis, Allergic, Seasonal; Sarcoidosis; Serum Sickness; Spondylitis; Spondylitis, Ankylosing; Stevens-Johnson Syndrome; Synovitis; Tennis Elbow; Tenosynovitis; Thrombocytopenia; Thyroiditis, Subacute; Trichinellosis; Tuberculosis, Meningeal; Tuberculosis, Pulmonary; Uveitis, Posterior

Glucocorticoid receptor agonist


Small molecule Approved MUSCULOSKELETAL; OTHER; RHEUMATOLOGY ORAL Liver Cirrhosis; Neoplasms; Peripheral Arterial Disease; Urogenital Neoplasms; Acute Coronary Syndrome; Amyotrophic Lateral Sclerosis; Atherosclerosis; Behcet Syndrome; Cholangiocarcinoma; Coronavirus Infections; Diabetic Nephropathies; Heart Diseases; Hepatitis C, Chronic; Hypertension; Intracranial Hemorrhages; Osteoarthritis, Knee; Pneumonia, Viral; Prostatic Neoplasms, Castration-Resistant; Renal Insufficiency, Chronic; Stomatitis, Aphthous; Vascular Diseases; Arrhythmias, Cardiac; Asthma; Atrial Fibrillation; Cardiovascular Diseases; Coronary Disease; Heart Failure; Liver Cirrhosis, Biliary; Lung Diseases; Multiple Myeloma; Myocardial Infarction; Non-ST Elevated Myocardial Infarction; Pericarditis; Postpericardiotomy Syndrome; Reperfusion Injury; Severe Acute Respiratory Syndrome; ST Elevation Myocardial Infarction; Vasculitis; Vitreoretinopathy, Proliferative; Familial Mediterranean Fever; Gout Tubulin inhibitor

Small molecule

Approved

MUSCULOSKELETAL; OTHER; RHEUMATOLOGY

ORAL

Liver Cirrhosis; Neoplasms; Peripheral Arterial Disease; Urogenital Neoplasms; Acute Coronary Syndrome; Amyotrophic Lateral Sclerosis; Atherosclerosis; Behcet Syndrome; Cholangiocarcinoma; Coronavirus Infections; Diabetic Nephropathies; Heart Diseases; Hepatitis C, Chronic; Hypertension; Intracranial Hemorrhages; Osteoarthritis, Knee; Pneumonia, Viral; Prostatic Neoplasms, Castration-Resistant; Renal Insufficiency, Chronic; Stomatitis, Aphthous; Vascular Diseases; Arrhythmias, Cardiac; Asthma; Atrial Fibrillation; Cardiovascular Diseases; Coronary Disease; Heart Failure; Liver Cirrhosis, Biliary; Lung Diseases; Multiple Myeloma; Myocardial Infarction; Non-ST Elevated Myocardial Infarction; Pericarditis; Postpericardiotomy Syndrome; Reperfusion Injury; Severe Acute Respiratory Syndrome; ST Elevation Myocardial Infarction; Vasculitis; Vitreoretinopathy, Proliferative; Familial Mediterranean Fever; Gout

Tubulin inhibitor


Small molecule Approved DIABETES DRUGS & ENDOCRINOLOGY; MUSCULOSKELETAL; OTHER; PREGNANCY AND GYNECOLOGY; RHEUMATOLOGY ORAL; TOPICAL; TRANSDERMAL; VAGINAL Blood Coagulation Disorders; Cerebral Arterial Diseases; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Polycystic Ovary Syndrome; Aging; Alzheimer Disease; Atherosclerosis; Bulimia Nervosa; Carcinoid Tumor; Depression, Postpartum; Depressive Disorder; Dry Eye Syndromes; Hereditary Breast and Ovarian Cancer Syndrome; HIV Infections; Migraine Disorders; Prostatic Neoplasms; Psychotic Disorders; Schizophrenia; Severe Acute Respiratory Syndrome; Triple Negative Breast Neoplasms; Urinary Tract Infections; Amenorrhea; Anorexia Nervosa; Bone Diseases, Metabolic; Coronary Disease; Dysmenorrhea; Endometriosis; Heart Diseases; Hot Flashes; Infertility; Multiple Sclerosis; Myocardial Ischemia; Non-alcoholic Fatty Liver Disease; Obesity; Pain; Prostatic Neoplasms, Castration-Resistant; Sexual Dysfunction, Physiological; Stress Disorders, Post-Traumatic; Turner Syndrome; Atrophic Vaginitis; Atrophy; Breast Neoplasms; Dyspareunia; Hypogonadism; Menopause; Osteoporosis; Osteoporosis, Postmenopausal; Primary Ovarian Insufficiency Estrogen receptor alpha agonist

Small molecule

Approved

DIABETES DRUGS & ENDOCRINOLOGY; MUSCULOSKELETAL; OTHER; PREGNANCY AND GYNECOLOGY; RHEUMATOLOGY

ORAL; TOPICAL; TRANSDERMAL; VAGINAL

Blood Coagulation Disorders; Cerebral Arterial Diseases; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Polycystic Ovary Syndrome; Aging; Alzheimer Disease; Atherosclerosis; Bulimia Nervosa; Carcinoid Tumor; Depression, Postpartum; Depressive Disorder; Dry Eye Syndromes; Hereditary Breast and Ovarian Cancer Syndrome; HIV Infections; Migraine Disorders; Prostatic Neoplasms; Psychotic Disorders; Schizophrenia; Severe Acute Respiratory Syndrome; Triple Negative Breast Neoplasms; Urinary Tract Infections; Amenorrhea; Anorexia Nervosa; Bone Diseases, Metabolic; Coronary Disease; Dysmenorrhea; Endometriosis; Heart Diseases; Hot Flashes; Infertility; Multiple Sclerosis; Myocardial Ischemia; Non-alcoholic Fatty Liver Disease; Obesity; Pain; Prostatic Neoplasms, Castration-Resistant; Sexual Dysfunction, Physiological; Stress Disorders, Post-Traumatic; Turner Syndrome; Atrophic Vaginitis; Atrophy; Breast Neoplasms; Dyspareunia; Hypogonadism; Menopause; Osteoporosis; Osteoporosis, Postmenopausal; Primary Ovarian Insufficiency

Estrogen receptor alpha agonist


Small molecule Approved DIABETES DRUGS & ENDOCRINOLOGY; MUSCULOSKELETAL; OTHER ORAL Atrophy; Breast Neoplasms; Hypogonadism; Menopause; Primary Ovarian Insufficiency Estrogen receptor agonist


Protein Approved MUSCULOSKELETAL; OTHER; PREGNANCY AND GYNECOLOGY INJECTION; NASAL Bone Diseases, Metabolic; Menopause; Osteoporosis; Bone Resorption; Hypercalcemia; Osteitis Deformans; Osteoporosis, Postmenopausal; Parathyroid Diseases Calcitonin receptor agonist


Small molecule Approved MUSCULOSKELETAL; OTHER; RHEUMATOLOGY ORAL Kidney Calculi; Renal Colic; Multiple Sclerosis; Paget Disease, Extramammary; Periodontitis; Bursitis; Inflammation; Low Back Pain; Migraine Disorders; Osteoarthritis, Knee; Postoperative Nausea and Vomiting; Sprains and Strains; Tendinopathy; Wounds and Injuries; Acute Pain; Arthralgia; Arthritis, Rheumatoid; Dysmenorrhea; Myalgia; Osteoarthritis; Rheumatic Diseases Cyclooxygenase inhibitor

Small molecule

Approved

MUSCULOSKELETAL; OTHER; RHEUMATOLOGY

ORAL

Kidney Calculi; Renal Colic; Multiple Sclerosis; Paget Disease, Extramammary; Periodontitis; Bursitis; Inflammation; Low Back Pain; Migraine Disorders; Osteoarthritis, Knee; Postoperative Nausea and Vomiting; Sprains and Strains; Tendinopathy; Wounds and Injuries; Acute Pain; Arthralgia; Arthritis, Rheumatoid; Dysmenorrhea; Myalgia; Osteoarthritis; Rheumatic Diseases

Cyclooxygenase inhibitor


Small molecule Approved DIABETES DRUGS & ENDOCRINOLOGY; MUSCULOSKELETAL; OTHER; RHEUMATOLOGY ORAL Lecithin Cholesterol Acyltransferase Deficiency; Carcinoma, Hepatocellular; Pancreatic Neoplasms; Colorectal Neoplasms; Muscular Diseases; Pain; Sprains and Strains; Acute Pain; Arthritis, Juvenile; Arthritis, Rheumatoid; Osteoarthritis; Rheumatic Diseases Cyclooxygenase-2 inhibitor


Small molecule Approved MUSCULOSKELETAL; OTHER; RHEUMATOLOGY ORAL Brain Neoplasms; Paraganglioma; Alzheimer Disease; Carcinoma, Non-Small-Cell Lung; Adenoma; Colorectal Neoplasms; Joint Diseases; Osteoarthritis; Osteoarthritis, Knee; Pain; Prostatic Neoplasms, Castration-Resistant; Stomach Neoplasms; Rheumatic Diseases Cyclooxygenase-2 inhibitor


Small molecule Approved MUSCULOSKELETAL; OTHER ORAL Lupus Erythematosus, Systemic; Dysmenorrhea; Osteoarthritis, Knee; Pharyngitis; Pregnancy; Toothache; Low Back Pain; Migraine Disorders; Pain; Prostatic Neoplasms; Shoulder Pain; Spondylitis, Ankylosing; Tuberculosis; Arthritis, Juvenile; Arthritis, Rheumatoid; Osteoarthritis; Rheumatic Diseases Cyclooxygenase-2 inhibitor


Small molecule Approved CANCER; DIABETES DRUGS & ENDOCRINOLOGY; MUSCULOSKELETAL; OTHER INJECTION; INTRAVENOUS; IV (INFUSION) Adenocarcinoma; Anemia, Sickle Cell; Chondrosarcoma; Menopause; Neuroblastoma; beta-Thalassemia; Bone Resorption; Carcinoma, Intraductal, Noninfiltrating; Complex Regional Pain Syndromes; Kidney Neoplasms; Leiomyosarcoma; Low Back Pain; Macular Degeneration; Mesothelioma; Nasopharyngeal Neoplasms; Osteosarcoma; Pancreatic Neoplasms; Primary Myelofibrosis; Progeria; Urogenital Neoplasms; Uterine Cervical Neoplasms; Arthritis, Rheumatoid; Bone Diseases, Metabolic; Bone Neoplasms; Breast Neoplasms; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Giant Cell Tumors; Lung Neoplasms; Lymphoma; Lymphoma, Non-Hodgkin; Neoplasms, Plasma Cell; Osteoarthritis, Hip; Osteogenesis Imperfecta; Osteonecrosis; Pain; Plasmacytoma; Sarcoma; Sarcoma, Ewing; Spinal Cord Injuries; Bone Diseases; Fractures, Bone; Hypercalcemia; Multiple Myeloma; Neoplasm Metastasis; Osteitis Deformans; Osteoporosis; Osteoporosis, Postmenopausal; Prostatic Neoplasms Farnesyl diphosphate synthase inhibitor

Small molecule

Approved

CANCER; DIABETES DRUGS & ENDOCRINOLOGY; MUSCULOSKELETAL; OTHER

INJECTION; INTRAVENOUS; IV (INFUSION)

Adenocarcinoma; Anemia, Sickle Cell; Chondrosarcoma; Menopause; Neuroblastoma; beta-Thalassemia; Bone Resorption; Carcinoma, Intraductal, Noninfiltrating; Complex Regional Pain Syndromes; Kidney Neoplasms; Leiomyosarcoma; Low Back Pain; Macular Degeneration; Mesothelioma; Nasopharyngeal Neoplasms; Osteosarcoma; Pancreatic Neoplasms; Primary Myelofibrosis; Progeria; Urogenital Neoplasms; Uterine Cervical Neoplasms; Arthritis, Rheumatoid; Bone Diseases, Metabolic; Bone Neoplasms; Breast Neoplasms; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Giant Cell Tumors; Lung Neoplasms; Lymphoma; Lymphoma, Non-Hodgkin; Neoplasms, Plasma Cell; Osteoarthritis, Hip; Osteogenesis Imperfecta; Osteonecrosis; Pain; Plasmacytoma; Sarcoma; Sarcoma, Ewing; Spinal Cord Injuries; Bone Diseases; Fractures, Bone; Hypercalcemia; Multiple Myeloma; Neoplasm Metastasis; Osteitis Deformans; Osteoporosis; Osteoporosis, Postmenopausal; Prostatic Neoplasms

Farnesyl diphosphate synthase inhibitor


Protein Approved DIABETES DRUGS & ENDOCRINOLOGY; MUSCULOSKELETAL; OTHER SUBCUTANEOUS Breast Neoplasms; Colorectal Neoplasms; Lung Neoplasms; Prostatic Neoplasms; Sarcoma; Fibrous Dysplasia, Polyostotic; Pituitary Diseases; Acromegaly Growth hormone receptor antagonist


Small molecule Approved EMERGENCY MEDICINE; MUSCULOSKELETAL; NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER ORAL Carcinoma, Squamous Cell; Cough; Essential Tremor; Marijuana Abuse; Oropharyngeal Neoplasms; Pregnancy; Refractive Errors; Tobacco Use Disorder; Alcoholism; Complex Regional Pain Syndromes; Dental Anxiety; Diabetes Mellitus; Dry Eye Syndromes; Irritable Bowel Syndrome; Nausea; Pancreatitis, Chronic; Pruritus; Urinary Bladder, Overactive; Anxiety; Breast Neoplasms; Burning Mouth Syndrome; Chronic Pain; Dementia; Depressive Disorder; Diabetic Neuropathies; Epilepsies, Partial; Epilepsy, Complex Partial; Epilepsy, Tonic-Clonic; Fractures, Bone; Headache; Herpes Zoster; Intervertebral Disc Degeneration; Migraine Disorders; Mononeuropathies; Muscle Cramp; Neuralgia, Postherpetic; Neurotic Disorders; Opioid-Related Disorders; Osteoarthritis; Pain; Peripheral Nervous System Diseases; Prostatitis; Radiculopathy; Restless Legs Syndrome; Schizophrenia; Sleep Initiation and Maintenance Disorders; Anxiety Disorders; Epilepsy; Fibromyalgia; Neuralgia; Seizures; Spinal Cord Injuries Voltage-gated calcium channel modulator

Small molecule

Approved

EMERGENCY MEDICINE; MUSCULOSKELETAL; NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER

ORAL

Carcinoma, Squamous Cell; Cough; Essential Tremor; Marijuana Abuse; Oropharyngeal Neoplasms; Pregnancy; Refractive Errors; Tobacco Use Disorder; Alcoholism; Complex Regional Pain Syndromes; Dental Anxiety; Diabetes Mellitus; Dry Eye Syndromes; Irritable Bowel Syndrome; Nausea; Pancreatitis, Chronic; Pruritus; Urinary Bladder, Overactive; Anxiety; Breast Neoplasms; Burning Mouth Syndrome; Chronic Pain; Dementia; Depressive Disorder; Diabetic Neuropathies; Epilepsies, Partial; Epilepsy, Complex Partial; Epilepsy, Tonic-Clonic; Fractures, Bone; Headache; Herpes Zoster; Intervertebral Disc Degeneration; Migraine Disorders; Mononeuropathies; Muscle Cramp; Neuralgia, Postherpetic; Neurotic Disorders; Opioid-Related Disorders; Osteoarthritis; Pain; Peripheral Nervous System Diseases; Prostatitis; Radiculopathy; Restless Legs Syndrome; Schizophrenia; Sleep Initiation and Maintenance Disorders; Anxiety Disorders; Epilepsy; Fibromyalgia; Neuralgia; Seizures; Spinal Cord Injuries

Voltage-gated calcium channel modulator


Enzyme Approved MUSCULOSKELETAL INJECTION Mucopolysaccharidoses; Mucopolysaccharidosis VI Dermatan sulfate hydrolytic enzyme


Small molecule Approved MUSCULOSKELETAL; OTHER ORAL Tourette Syndrome; Movement Disorders; Chorea; Huntington Disease Synaptic vesicular amine transporter inhibitor


Small molecule Approved MUSCULOSKELETAL ORAL Cerebral Palsy; Motor Neuron Disease; Optic Neuritis; Renal Insufficiency; Carpal Tunnel Syndrome; Guillain-Barre Syndrome; Memory, Short-Term; Muscular Atrophy, Spinal; Prostatic Diseases; Sleep Apnea, Obstructive; Trauma, Nervous System; Wounds and Injuries; Ischemic Stroke; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Muscle Spasticity; Spinal Cord Injuries; Stroke; Multiple Sclerosis Voltage-gated potassium channel blocker

Small molecule

Approved

MUSCULOSKELETAL

ORAL

Cerebral Palsy; Motor Neuron Disease; Optic Neuritis; Renal Insufficiency; Carpal Tunnel Syndrome; Guillain-Barre Syndrome; Memory, Short-Term; Muscular Atrophy, Spinal; Prostatic Diseases; Sleep Apnea, Obstructive; Trauma, Nervous System; Wounds and Injuries; Ischemic Stroke; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Muscle Spasticity; Spinal Cord Injuries; Stroke; Multiple Sclerosis

Voltage-gated potassium channel blocker


Enzyme Approved MUSCULOSKELETAL INJECTION Diabetic Foot; Tendinopathy; Bursitis; Contracture; Lipoma; Urethral Stricture; Edema; Pressure Ulcer; Dupuytren Contracture; Penile Induration; Skin Ulcer; Ulcer Collagen hydrolytic enzyme


Small molecule Approved MUSCULOSKELETAL ORAL Astrocytoma; Breast Neoplasms; Cerebral Hemorrhage; Glioblastoma; Renal Insufficiency; Rett Syndrome; Asthma; Optic Neuritis; Schizophrenia; Severe Acute Respiratory Syndrome; Stroke; Uveitis; Multiple Sclerosis; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating Unknown

Small molecule

Approved

MUSCULOSKELETAL

ORAL

Astrocytoma; Breast Neoplasms; Cerebral Hemorrhage; Glioblastoma; Renal Insufficiency; Rett Syndrome; Asthma; Optic Neuritis; Schizophrenia; Severe Acute Respiratory Syndrome; Stroke; Uveitis; Multiple Sclerosis; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating

Unknown


Antibody Approved MUSCULOSKELETAL; PREGNANCY AND GYNECOLOGY SUBCUTANEOUS Crohn Disease; Kidney Diseases; Ovarian Neoplasms; Aortic Valve Stenosis; Carcinoma, Non-Small-Cell Lung; Colorectal Neoplasms; Fibrous Dysplasia of Bone; Gout; Histiocytosis, Langerhans-Cell; Hypersensitivity; Infertility, Male; Inflammatory Breast Neoplasms; Melanoma; Multiple Myeloma; Neoplasms; Osteoarthritis, Hip; Osteolysis; Osteosarcoma; Thyroid Neoplasms; Anorexia Nervosa; Arthritis, Rheumatoid; Bone Diseases, Metabolic; Carcinoma; Carcinoma, Renal Cell; Diabetes Mellitus; Fractures, Bone; Lung Neoplasms; Osteogenesis Imperfecta; Prostatic Neoplasms, Castration-Resistant; Bone Diseases; Bone Resorption; Breast Neoplasms; Giant Cell Tumor of Bone; Giant Cell Tumors; Hypercalcemia; Neoplasm Metastasis; Neoplasms, Bone Tissue; Osteoporosis; Osteoporosis, Postmenopausal Tumor necrosis factor ligand superfamily member 11 inhibitor

Antibody

Approved

MUSCULOSKELETAL; PREGNANCY AND GYNECOLOGY

SUBCUTANEOUS

Crohn Disease; Kidney Diseases; Ovarian Neoplasms; Aortic Valve Stenosis; Carcinoma, Non-Small-Cell Lung; Colorectal Neoplasms; Fibrous Dysplasia of Bone; Gout; Histiocytosis, Langerhans-Cell; Hypersensitivity; Infertility, Male; Inflammatory Breast Neoplasms; Melanoma; Multiple Myeloma; Neoplasms; Osteoarthritis, Hip; Osteolysis; Osteosarcoma; Thyroid Neoplasms; Anorexia Nervosa; Arthritis, Rheumatoid; Bone Diseases, Metabolic; Carcinoma; Carcinoma, Renal Cell; Diabetes Mellitus; Fractures, Bone; Lung Neoplasms; Osteogenesis Imperfecta; Prostatic Neoplasms, Castration-Resistant; Bone Diseases; Bone Resorption; Breast Neoplasms; Giant Cell Tumor of Bone; Giant Cell Tumors; Hypercalcemia; Neoplasm Metastasis; Neoplasms, Bone Tissue; Osteoporosis; Osteoporosis, Postmenopausal

Tumor necrosis factor ligand superfamily member 11 inhibitor


Small molecule Approved MUSCULOSKELETAL; OTHER ORAL Celiac Disease; Kidney Diseases; Paraparesis, Tropical Spastic; Purpura, Thrombocytopenic, Idiopathic; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis; Multiple Sclerosis, Relapsing-Remitting Dihydroorotate dehydrogenase inhibitor


Small molecule Approved IMMUNE SYSTEM; MUSCULOSKELETAL; OTHER ORAL Gliosarcoma; Leukemia, Lymphocytic, Chronic, B-Cell; Arthritis, Psoriatic; Arthritis, Rheumatoid; Cerebral Hemorrhage; Ischemic Stroke; Lymphoma, T-Cell, Cutaneous; Sleep Apnea, Obstructive; Multiple Sclerosis, Chronic Progressive; Severe Acute Respiratory Syndrome; Immune System Diseases; Multiple Sclerosis; Multiple Sclerosis, Relapsing-Remitting; Psoriasis Kelch-like ECH-associated protein 1 inhibitor

Small molecule

Approved

IMMUNE SYSTEM; MUSCULOSKELETAL; OTHER

ORAL

Gliosarcoma; Leukemia, Lymphocytic, Chronic, B-Cell; Arthritis, Psoriatic; Arthritis, Rheumatoid; Cerebral Hemorrhage; Ischemic Stroke; Lymphoma, T-Cell, Cutaneous; Sleep Apnea, Obstructive; Multiple Sclerosis, Chronic Progressive; Severe Acute Respiratory Syndrome; Immune System Diseases; Multiple Sclerosis; Multiple Sclerosis, Relapsing-Remitting; Psoriasis

Kelch-like ECH-associated protein 1 inhibitor


Combination Approved MUSCULOSKELETAL; NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER ORAL Unknown Unknown


Combination Approved MUSCULOSKELETAL; OTHER; PREGNANCY AND GYNECOLOGY ORAL; ORAL-21; ORAL-28 Unknown Unknown


Combination Approved MUSCULOSKELETAL; OTHER ORAL; TRANSDERMAL Unknown Unknown


Combination Approved MUSCULOSKELETAL ORAL Unknown Unknown


Combination Approved MUSCULOSKELETAL; OTHER; RHEUMATOLOGY ORAL Unknown Unknown


Combination Approved DIABETES DRUGS & ENDOCRINOLOGY; MUSCULOSKELETAL; OTHER; PREGNANCY AND GYNECOLOGY ORAL-28 Unknown Unknown


Unknown Approved DERMATOLOGY; MUSCULOSKELETAL; OTHER SINGLE-USE Unknown Unknown