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Total: 23
Small molecule
Approved
EYE; OTHER
INTRAOCULAR; INTRAVITREAL; OPHTHALMIC; ORAL; TOPICAL
Hypertension; Radius Fractures; Tooth Diseases; Adrenal Insufficiency; Aortic Coarctation; Brain Edema; Esophageal Neoplasms; Graves Disease; Head and Neck Neoplasms; Heart Failure; Lacrimal Apparatus Diseases; Lung Neoplasms; Lymphoma, T-Cell, Cutaneous; Meningeal Carcinomatosis; Osteoarthritis, Knee; Rheumatic Diseases; Rotator Cuff Injuries; Scleritis; Vitiligo; Appendicitis; Blast Crisis; Brain Neoplasms; Breast Carcinoma In Situ; Breast Neoplasms; Burkitt Lymphoma; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Castleman Disease; Cholangiocarcinoma; Dry Eye Syndromes; Dyspnea; Endocrine Gland Neoplasms; Endometrial Neoplasms; Fasciitis, Plantar; Glomerulonephritis; Gout; Hearing Loss; Hearing Loss, Sensorineural; Hematologic Neoplasms; Hematoma, Subdural, Intracranial; Hemorrhage; Histiocytosis, Langerhans-Cell; Histiocytosis, Sinus; Intestinal Obstruction; Intracranial Hypertension; Kidney Diseases; Leptospirosis; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Lymphoid; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Plasma Cell; Leukemia, T-Cell; Lichen Planus; Liposarcoma, Myxoid; Liver Neoplasms; Lymphoma, Large-Cell, Anaplastic; Lymphoma, T-Cell, Peripheral; Macular Degeneration; Melanoma; Meningitis; Meningitis, Cryptococcal; Mesothelioma; Mouth Neoplasms; Nasopharyngeal Neoplasms; Neck Pain; Neoplasm Metastasis; Nervous System Diseases; Pancreatic Neoplasms; POEMS Syndrome; Premature Birth; Pulmonary Fibrosis; Purpura, Schoenlein-Henoch; Purpura, Thrombotic Thrombocytopenic; Radiculopathy; Rectal Neoplasms; Red-Cell Aplasia, Pure; Respiratory Tract Diseases; Retinal Vein Occlusion; Sciatica; Stomach Neoplasms; Tonsillitis; Toxoplasmosis, Cerebral; Tuberculosis; Urinary Bladder Neoplasms; Uveitis, Intermediate; Wet Macular Degeneration; Xerostomia; Amyloidosis; Amyloidosis, Familial; Anemia; Anemia, Refractory; Anemia, Refractory, with Excess of Blasts; Anemia, Sickle Cell; Atrioventricular Block; Back Pain; Blepharitis; Bronchiolitis; Bronchopulmonary Dysplasia; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Cataract; Chronic Pain; Colorectal Neoplasms; Conjunctivitis, Viral; Cysticercosis; Deafness; Deglutition Disorders; Dermatitis; Encephalitis, Herpes Simplex; Fatigue; Genital Neoplasms, Female; Glaucoma; Glomerulosclerosis, Focal Segmental; Graft vs Host Disease; Granuloma, Lethal Midline; Headache; HELLP Syndrome; Hernias, Diaphragmatic, Congenital; Hodgkin Disease; Hypersensitivity; Knee Injuries; Leiomyoma; Leukemia, Biphenotypic, Acute; Leukemia, Erythroblastic, Acute; Leukemia, Megakaryoblastic, Acute; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Leukemia, Myelomonocytic, Chronic; Leukemia, Promyelocytic, Acute; Lichen Planus, Oral; Liver Cirrhosis; Lymphohistiocytosis, Hemophagocytic; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Malaria; Mastoiditis; Meniere Disease; Migraine Disorders; Multiple Myeloma; Myelodysplastic Syndromes; Nausea; Nephrosis; Neuralgia; Otitis Externa; Otitis Media; Ovarian Hyperstimulation Syndrome; Ovarian Neoplasms; Pain; Pelvic Organ Prolapse; Plasmacytoma; Pneumonia, Viral; Postoperative Nausea and Vomiting; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Renal Insufficiency, Chronic; Respiratory Distress Syndrome; Rhinitis, Allergic, Perennial; Sarcoma; Severe Acute Respiratory Syndrome; Small Cell Lung Carcinoma; Smoldering Multiple Myeloma; Specific Language Disorder; Strabismus; Urinary Tract Infections; Uveitis, Anterior; Vaginosis, Bacterial; Vitreoretinopathy, Proliferative; Vomiting; Waldenstrom Macroglobulinemia; Wounds and Injuries; Acne Vulgaris; Addison Disease; Adrenal Hyperplasia, Congenital; Adrenocortical Hyperfunction; Anemia, Aplastic; Anemia, Hemolytic; Arthritis, Gouty; Arthritis, Juvenile; Arthritis, Psoriatic; Arthritis, Rheumatoid; Asthma; Bursitis; Chorioretinitis; Choroiditis; Colitis, Ulcerative; Conjunctivitis, Allergic; Crohn Disease; Dermatitis, Atopic; Dermatitis, Contact; Dermatitis, Exfoliative; Dermatitis Herpetiformis; Dermatitis, Seborrheic; Diabetic Retinopathy; Erythema Multiforme; Eye Diseases; Hemorrhoids; Herpes Zoster Ophthalmicus; Hypercalcemia; Infections; Inflammation; Iridocyclitis; Iritis; Keratitis; Leukemia; Lupus Erythematosus, Systemic; Lymphoma; Macular Edema; Multiple Sclerosis; Mycosis Fungoides; Myocarditis; Nasal Obstruction; Neoplasms; Nephrotic Syndrome; Ophthalmia, Sympathetic; Optic Neuritis; Osteoarthritis; Pemphigus; Peptic Ulcer; Pneumonia; Psoriasis; Pulmonary Eosinophilia; Purpura, Thrombocytopenic, Idiopathic; Rhinitis, Allergic, Seasonal; Sarcoidosis; Serum Sickness; Spondylitis, Ankylosing; Stevens-Johnson Syndrome; Synovitis; Tennis Elbow; Tenosynovitis; Thrombocytopenia; Thyroiditis, Subacute; Trichinellosis; Tuberculosis, Meningeal; Tuberculosis, Pulmonary; Uveitis, Posterior
Glucocorticoid receptor agonist
Small molecule
Approved
EYE; OTHER
OPHTHALMIC
Rectal Neoplasms; Breast Neoplasms; Cholangiocarcinoma; Esophageal Neoplasms; Colorectal Neoplasms; Eye Infections; Herpes Simplex; Keratoconjunctivitis; Neoplasms
DNA inhibitor
Small molecule
Approved
EYE; OTHER
IMPLANTATION; OPHTHALMIC; ORAL
Central Nervous System Neoplasms; Kidney Diseases; Melanoma; Mesothelioma; Neuroblastoma; Carcinoma, Hepatocellular; Diabetes Mellitus, Type 1; Fallopian Tube Neoplasms; Glioblastoma; Graft vs Host Disease; Lymphoma; Ovarian Neoplasms; Peritoneal Neoplasms; Conjunctivitis; Cytomegalovirus Infections; Infections; Acquired Immunodeficiency Syndrome; Cytomegalovirus Retinitis; Eye Infections; HIV Infections; Primary Immunodeficiency Diseases; Retinitis; Virus Diseases
Human herpesvirus 1 DNA polymerase inhibitor
Small molecule
Approved
ENT; EYE; OTHER; PEDIATRICS; PREGNANCY AND GYNECOLOGY
INJECTION; OPHTHALMIC; ORAL; OTIC
Osteomyelitis; Hearing Loss; Conjunctivitis, Bacterial; Diabetic Foot; Glaucoma; Glaucoma, Open-Angle; Ocular Hypertension; Otitis Media; Pelvic Inflammatory Disease; Urinary Tract Infections; Bacterial Infections; Eye Infections; Infections
Bacterial DNA gyrase inhibitor
Small molecule
Approved
EYE; IMMUNE SYSTEM; OTHER
INJECTION; OPHTHALMIC; ORAL
Obesity; Osteomyelitis; Anemia, Sickle Cell; Graves Ophthalmopathy; Hemorrhagic Fever, Ebola; Immune System Diseases; Respiratory Distress Syndrome; Sepsis; Toxoplasmosis, Cerebral; Bronchiolitis; Crohn Disease; Gastrointestinal Hemorrhage; Gastroparesis; Multiple Sclerosis; Neoplasms; Obsessive-Compulsive Disorder; Onchocerciasis; Periodontitis; Respiratory Syncytial Virus Infections; Sarcoidosis; Tuberculosis; Abdominal Pain; Acne Vulgaris; Arthritis, Reactive; Asthma; Blepharitis; Bronchial Diseases; Bronchiectasis; Bronchiolitis Obliterans; Bronchopulmonary Dysplasia; Chlamydia Infections; Conjunctivitis, Inclusion; Coronary Disease; Coronavirus Infections; Cough; Diarrhea; Digestive System Diseases; Eye Diseases; Fever; Gonorrhea; Inflammation; Lung Diseases; Malaria; Malaria, Falciparum; Malnutrition; Maxillary Sinusitis; Mycobacterium avium-intracellulare Infection; Mycobacterium Infections; Mycoses; Myocardial Infarction; Neonatal Sepsis; Otitis Media, Suppurative; Pneumonia, Viral; Pregnancy; Premature Birth; Respiratory Insufficiency; Severe Acute Respiratory Syndrome; Syphilis; Vomiting; Yaws; Bacterial Infections; Bronchitis, Chronic; Conjunctivitis, Bacterial; Cystic Fibrosis; Eye Infections; Fibrosis; HIV Infections; Infections; Otitis Media; Pelvic Inflammatory Disease; Pharyngitis; Pneumonia; Pulmonary Disease, Chronic Obstructive; Sinusitis; Sprains and Strains; Tonsillitis; Ulcer; Urethritis; Uterine Cervicitis
Bacterial 70S ribosome inhibitor
Small molecule
Approved
EYE; IMMUNE SYSTEM; OTHER
INJECTION
Herpes Simplex; Kidney Diseases; Uterine Cervical Neoplasms; Anus Neoplasms; Infections; Papilloma; Sarcoma; Uterine Cervical Dysplasia; Cytomegalovirus Infections; Cytomegalovirus Retinitis; Primary Immunodeficiency Diseases; Virus Diseases
Human herpesvirus 1 DNA polymerase inhibitor
Small molecule
Approved
EYE; OTHER; UROLOGY AND KIDNEY
INJECTION; OPHTHALMIC; ORAL
Osteomyelitis; Endophthalmitis; Escherichia coli Infections; HIV Infections; Kidney Diseases; Urinary Bladder, Overactive; Appendicitis; Cellulitis; Diabetic Foot; Lymphoma, Non-Hodgkin; Neoplasms; Sarcoidosis; Tuberculosis, Multidrug-Resistant; Cataract; Cystic Fibrosis; Dyspepsia; Endocarditis; Fever; Helicobacter Infections; Hot Flashes; Maxillary Sinusitis; Neutropenia; Otitis Media; Pelvic Inflammatory Disease; Pneumonia, Bacterial; Prostatic Hyperplasia; Prostatitis; Pulmonary Disease, Chronic Obstructive; Pyelonephritis; Skin Diseases; Staphylococcal Infections; Tuberculosis; Acne Vulgaris; Bacterial Infections; Bronchitis, Chronic; Conjunctivitis, Bacterial; Corneal Ulcer; Eye Infections; Infections; Otitis Externa; Pneumonia; Sinusitis; Urinary Tract Infections
DNA gyrase inhibitor
Oligonucleotide
Approved
EYE
INJECTION
Cytomegalovirus Retinitis; Eye Infections
Major intermediate early region 2 mRNA antisense inhibitor
Small molecule
Approved
EYE; OTHER
OPHTHALMIC
Osteomyelitis; Cataract; Tuberculosis; Bacterial Infections; Conjunctivitis, Bacterial; Eye Infections; Infections
DNA gyrase inhibitor
Small molecule
Approved
EYE; OTHER
OPHTHALMIC
Chronic Pain; Conjunctivitis, Allergic; Dermatitis; Dermatitis, Atopic; Fractures, Bone; Rhinitis, Allergic, Perennial
Histamine H1 receptor antagonist
Small molecule
Approved
EYE
OPHTHALMIC
Macular Degeneration; Retinitis Pigmentosa; Glaucoma
Unknown
Small molecule
Approved
EYE
INJECTION
Central Nervous System Neoplasms; Glioblastoma; Melanoma; Pleural Effusion; Prostatic Neoplasms, Castration-Resistant; Breast Neoplasms; Histoplasmosis; Pancreatic Neoplasms; Basal Cell Nevus Syndrome; Carcinoma, Basal Cell; Macular Degeneration; Myopia, Degenerative; Retinal Neovascularization; Wet Macular Degeneration
DNA inhibitor
Small molecule
Approved
EYE; OTHER
OPHTHALMIC
Exfoliation Syndrome; Glaucoma; Glaucoma, Open-Angle; Ocular Hypertension
Prostanoid FP receptor agonist
Small molecule
Approved
EYE; OTHER
OPHTHALMIC; TOPICAL
Vitiligo; Alopecia; Graves Ophthalmopathy; Glaucoma; Glaucoma, Open-Angle; Hypotrichosis; Ocular Hypertension
Prostanoid FP receptor agonist
Antibody
Approved
EYE
INJECTION
Angioid Streaks; Central Serous Chorioretinopathy; Conjunctival Neoplasms; Corneal Neovascularization; Glaucoma, Open-Angle; Myopia; Optic Neuropathy, Ischemic; Port-Wine Stain; von Hippel-Lindau Disease; Diabetes Mellitus; Histoplasmosis; Pterygium; Retinal Detachment; Retinal Diseases; Retinoblastoma; Telangiectasis; Blindness; Glaucoma; Glaucoma, Neovascular; Macular Degeneration; Myopia, Degenerative; Retinal Vein Occlusion; Retinopathy of Prematurity; Diabetic Retinopathy; Macular Edema; Retinal Neovascularization; Wet Macular Degeneration
Vascular endothelial growth factor A inhibitor
Small molecule
Approved
EYE
OPHTHALMIC
Dry Eye Syndromes; Cataract; Panuveitis; Uveitis; Inflammation; Uveitis, Anterior
Glucocorticoid receptor agonist
Enzyme
Approved
EYE
INTRAVITREAL
Retinal Vein Occlusion; Uveitis; Macular Degeneration; Stroke; Venous Thrombosis; Retinal Perforations; Eye Diseases
Collagen hydrolytic enzyme
Protein
Approved
EYE
INJECTION
Carcinoma, Non-Small-Cell Lung; Corneal Neovascularization; Glioma; Histoplasmosis; Lymphoma; Lymphoma, Non-Hodgkin; Adenocarcinoma, Follicular; Astrocytoma; Breast Neoplasms; Carcinoid Tumor; Carcinoma, Renal Cell; Central Serous Chorioretinopathy; Colonic Neoplasms; Endometrial Neoplasms; Gliosarcoma; Graves Ophthalmopathy; Leukemia; Multiple Myeloma; Oligodendroglioma; Pseudoxanthoma Elasticum; Rectal Neoplasms; Retinal Diseases; Small Cell Lung Carcinoma; Thyroid Neoplasms; Urethral Neoplasms; Urinary Bladder Neoplasms; Vitreous Hemorrhage; Glaucoma; Glaucoma, Neovascular; Melanoma; Myopia, Degenerative; Retinal Vein Occlusion; Retinopathy of Prematurity; Telangiectasis; Colorectal Neoplasms; Diabetic Retinopathy; Macular Degeneration; Macular Edema; Neoplasms; Retinal Neovascularization; Wet Macular Degeneration
Placenta growth factor inhibitor
Small molecule
Approved
EYE
OPHTHALMIC
Glaucoma; Glaucoma, Open-Angle; Ocular Hypertension
Prostanoid FP receptor agonist
Small molecule
Approved
EYE
ORAL
Kidney Diseases; Liver Diseases; Depressive Disorder, Major; Sleep Disorders, Circadian Rhythm; Sleep Initiation and Maintenance Disorders; Sleep Wake Disorders; Smith-Magenis Syndrome
Melatonin receptor agonist
Combination
Approved
EYE
IRRIGATION
Unknown
Unknown
Combination
Approved
EYE; OTHER
OPHTHALMIC
Unknown
Unknown
Combination
Approved
EYE; OTHER
INJECTION; IRRIGATION
Unknown
Unknown