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Total: 43
Small molecule
Approved
OTHER; PEDIATRICS; RESPIRATORY
DENTAL; INHALATION; INJECTION; INTRA-ARTICULAR; INTRAMUSCULAR; INTRAVITREAL; NASAL; SUSPENSION; TOPICAL
Humeral Fractures; Papilledema; Tendon Entrapment; Fibroma; Hearing Loss; Mucositis; Neurilemmoma; Rotator Cuff Injuries; Alopecia Areata; Cataract; Dermatitis, Atopic; Diabetic Retinopathy; Glaucoma; Hand Dermatoses; Keloid; Lichen Planus; Pemphigoid, Benign Mucous Membrane; Shoulder Pain; Vitiligo; Chalazion; Cough; Cystitis, Interstitial; Dupuytren Contracture; Eye Injuries; Lichen Planus, Oral; Macular Degeneration; Macular Edema; Optic Neuropathy, Ischemic; Osteoarthritis, Hip; Osteoarthritis, Knee; Otitis Media with Effusion; Pemphigus; Radiculopathy; Retinal Vein Occlusion; Rhinitis; Tendinopathy; Uveitis; Vitreoretinopathy, Proliferative; Wet Macular Degeneration; Anemia; Arthritis, Gouty; Arthritis, Rheumatoid; Asthma; Bursitis; Dermatitis; Gout; Multiple Sclerosis; Mycoses; Nasal Obstruction; Osteoarthritis; Pain; Rhinitis, Allergic, Seasonal; Serum Sickness; Skin Diseases; Tennis Elbow; Tenosynovitis; Tuberculosis, Pulmonary; Wounds and Injuries
Glucocorticoid receptor agonist
Small molecule
Approved
OTHER; RESPIRATORY
INHALATION; OPHTHALMIC
Osteomyelitis; Bronchopulmonary Dysplasia; Dry Eye Syndromes; Renal Insufficiency, Chronic; Bronchiectasis; Pneumonia, Bacterial; Blepharitis; Cataract; Conjunctivitis, Bacterial; Fractures, Bone; Pneumonia; Pseudomonas Infections; Bacterial Infections; Conjunctivitis, Allergic; Cystic Fibrosis; Eye Infections; Infections; Inflammation
70S ribosome inhibitor
Small molecule
Approved
OTHER; RESPIRATORY
ORAL
Hypersensitivity; Multiple Sclerosis; Common Cold; Rhinitis, Allergic; Rhinitis, Allergic, Seasonal; Urticaria
Histamine H1 receptor antagonist
Small molecule
Approved
OTHER; RESPIRATORY
INHALATION
Depressive Disorder, Major; Diabetes Mellitus; Glycogen Storage Disease Type II; Idiopathic Pulmonary Fibrosis; Kartagener Syndrome; Lymphangioleiomyomatosis; Myasthenic Syndromes, Congenital; Bronchiolitis; Cough; Familial Primary Pulmonary Hypertension; Hypersensitivity; Memory Disorders; Pulmonary Edema; Respiratory Insufficiency; Spinal Cord Injuries; Status Asthmaticus; Dysautonomia, Familial; Heart Failure; Hypertension, Pulmonary; Lung Diseases; Organophosphate Poisoning; Rhinitis, Allergic, Seasonal; Asthma; Asthma, Exercise-Induced; Bronchial Spasm; Lung Diseases, Obstructive; Pulmonary Disease, Chronic Obstructive
Beta-2 adrenergic receptor agonist
Small molecule
Approved
OTHER; RESPIRATORY
INHALATION; INJECTION
Osteomyelitis; Renal Insufficiency; Gonorrhea; Enterobacteriaceae Infections; Skin Diseases; Bacterial Infections; Cystic Fibrosis; Infections; Intraabdominal Infections; Pneumonia; Pyelonephritis; Sepsis; Urinary Tract Infections
Bacterial penicillin-binding protein inhibitor
Small molecule
Approved
GASTROINTESTINAL; OTHER; RESPIRATORY
INJECTION; ORAL; OTIC
Hepatitis, Alcoholic; Liver Cirrhosis, Alcoholic; Osteomyelitis; Rhinoscleroma; Carcinoma, Pancreatic Ductal; Diabetic Foot; Escherichia coli Infections; Hearing Loss; Hepatitis C; Leukemia, Myeloid, Acute; Lung Diseases; Lymphoma; Neoplasms; Periapical Periodontitis; Pseudomonas Infections; Purpura, Thrombocytopenic, Idiopathic; Amyotrophic Lateral Sclerosis; Anthrax; Cataract; Crohn Disease; Cystic Fibrosis; Leukemia, Lymphocytic, Chronic, B-Cell; Plague; Abscess; Breast Neoplasms; Bronchiectasis; Communicable Diseases; Diarrhea; Digestive System Diseases; Fever; Liver Abscess; Neutropenia; Otitis Media; Peritonitis; Pneumonia; Prostatic Neoplasms, Castration-Resistant; Pulmonary Disease, Chronic Obstructive; Sepsis; Urinary Bladder Neoplasms; Urolithiasis; Bacterial Infections; Bronchitis, Chronic; Cystitis; Eye Infections; Gonorrhea; Infections; Intraabdominal Infections; Otitis Externa; Prostatitis; Pyelonephritis; Sinusitis; Typhoid Fever; Urinary Tract Infections
Bacterial DNA gyrase inhibitor
Small molecule
Approved
OTHER; RESPIRATORY
ORAL
Osteomyelitis; Bronchitis, Chronic; Infections; Maxillary Sinusitis; Otitis Media; Pharyngitis; Pneumonia; Sinusitis; Tonsillitis; Urinary Tract Infections
Bacterial penicillin-binding protein inhibitor
Small molecule
Approved
IMMUNE SYSTEM; OTHER; RESPIRATORY
ORAL
Osteomyelitis; Anovulation; Depressive Disorder, Major; HIV Infections; Neoplasm Metastasis; Neoplasms; Parkinson Disease; Prostatic Neoplasms, Castration-Resistant; Venous Thromboembolism; Buruli Ulcer; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cystic Fibrosis; Idiopathic Hypersomnia; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma; Lymphoma, B-Cell, Marginal Zone; Narcolepsy; Periodontitis; Pseudomyxoma Peritonei; Severe Acute Respiratory Syndrome; Toxoplasmosis, Cerebral; Asthma; Bronchiolitis Obliterans; Bronchopulmonary Dysplasia; Crohn Disease; Gastritis; Heart Diseases; Helicobacter Infections; Hemorrhage; Lymphoma, Non-Hodgkin; Multiple Myeloma; Mycobacterium avium-intracellulare Infection; Pneumonia, Bacterial; Sepsis; Shock, Septic; Stomach Neoplasms; Stomach Ulcer; Tuberculosis; Bacterial Infections; Bronchitis, Chronic; Duodenal Ulcer; Infections; Maxillary Sinusitis; Otitis Media; Pharyngitis; Pneumonia; Sinusitis; Tonsillitis
Bacterial 70S ribosome inhibitor
Small molecule
Approved
CANCER; OTHER; RESPIRATORY
INJECTION; IV (INFUSION)
Anus Neoplasms; Brain Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Carcinoma, Renal Cell; Carcinoma, Small Cell; Carcinoma, Verrucous; Coronary Restenosis; Genital Neoplasms, Female; Glioblastoma; Gliosarcoma; Hodgkin Disease; Hypopharyngeal Neoplasms; Leukemia, Lymphocytic, Chronic, B-Cell; Liver Neoplasms; Mesothelioma; Rectal Neoplasms; Vaginal Neoplasms; Adenocarcinoma; Adenocarcinoma, Bronchiolo-Alveolar; Adrenal Cortex Neoplasms; Arthritis, Rheumatoid; Biliary Tract Neoplasms; Breast Carcinoma In Situ; Carcinoma, Ductal; Carcinoma, Hepatocellular; Carcinoma, Merkel Cell; Carcinoma, Neuroendocrine; Central Nervous System Neoplasms; Cervical Intraepithelial Neoplasia; Cholangiocarcinoma; Colorectal Neoplasms; Constriction, Pathologic; Cystadenoma, Serous; Digestive System Diseases; Gallbladder Neoplasms; Gastrointestinal Stromal Tumors; Hemangiosarcoma; Hereditary Breast and Ovarian Cancer Syndrome; Keratosis, Actinic; Kidney Neoplasms; Leukemia; Lymphoma; Mouth Neoplasms; Multiple Myeloma; Neoplasms, Germ Cell and Embryonal; Oropharyngeal Neoplasms; Penile Neoplasms; Peripheral Vascular Diseases; Prostatic Hyperplasia; Prostatic Neoplasms; Psoriasis; Salivary Gland Neoplasms; Small Cell Lung Carcinoma; Squamous Cell Carcinoma of Head and Neck; Thymoma; Vulvar Neoplasms; Adenocarcinoma of Lung; Anemia; Breast Neoplasms, Male; Carcinoma, Endometrioid; Carcinoma, Large Cell; Carcinoma, Pancreatic Ductal; Carcinoma, Squamous Cell; Endometrial Neoplasms; Esophageal Neoplasms; Fallopian Tube Neoplasms; Gestational Trophoblastic Disease; Head and Neck Neoplasms; HIV Infections; Hypersensitivity; Inflammatory Breast Neoplasms; Ischemia; Lung Neoplasms; Lymphoma, Non-Hodgkin; Melanoma; Nasopharyngeal Neoplasms; Neoplasm Metastasis; Ovarian Neoplasms; Pain; Pancreatic Neoplasms; Peripheral Arterial Disease; Peripheral Nervous System Diseases; Peritoneal Neoplasms; Prostatic Neoplasms, Castration-Resistant; Retroviridae Infections; Sarcoma; Sarcoma, Kaposi; Sex Cord-Gonadal Stromal Tumors; Stomach Neoplasms; Teratoma; Testicular Neoplasms; Thyroid Neoplasms; Triple Negative Breast Neoplasms; Urethral Neoplasms; Urinary Bladder Neoplasms; Urogenital Neoplasms; Uterine Cervical Neoplasms; Uterine Neoplasms; Breast Neoplasms; Carcinoma; Carcinoma, Non-Small-Cell Lung; Neoplasms
Tubulin inhibitor
Enzyme
Approved
RESPIRATORY
UNKNOWN
Head and Neck Neoplasms; Cough; Dry Eye Syndromes; Graft vs Host Disease; Pleural Effusion; Sjogren's Syndrome; Asthma; Hypoxia; Infections; Ischemic Stroke; Empyema; Empyema, Pleural; Respiratory Distress Syndrome; Severe Acute Respiratory Syndrome; Sinusitis; Wounds and Injuries; Cystic Fibrosis
DNA hydrolytic enzyme
Small molecule
Approved
GASTROINTESTINAL; OTHER; RESPIRATORY
INHALATION; NASAL; ORAL; RECTAL
Cholangitis, Sclerosing; Snoring; Aspergillosis, Allergic Bronchopulmonary; Breast Neoplasms; Bronchiolitis Obliterans; Diarrhea; Esophageal Stenosis; Glomerulonephritis, IGA; Hepatitis, Autoimmune; Hypersensitivity; Lung Neoplasms; Malnutrition; Melanoma; Nasal Polyps; Radiation Pneumonitis; Respiratory Distress Syndrome; Status Asthmaticus; Altitude Sickness; Bronchopulmonary Dysplasia; Colitis, Collagenous; Colitis, Lymphocytic; Colitis, Microscopic; Eosinophilic Esophagitis; Graft vs Host Disease; Liver Cirrhosis, Biliary; Proctitis; Proctocolitis; Respiratory Tract Diseases; Severe Acute Respiratory Syndrome; Sinusitis; Sleep Apnea, Obstructive; Asthma; Bronchitis, Chronic; Colitis, Ulcerative; Crohn Disease; Emphysema; Lung Diseases, Obstructive; Nasal Obstruction; Pulmonary Disease, Chronic Obstructive; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal
Glucocorticoid receptor agonist
Small molecule
Approved
RESPIRATORY
ORAL
Osteomyelitis; Bacterial Infections
Bacterial DNA gyrase inhibitor
Small molecule
Approved
OTHER; RESPIRATORY
ORAL
Breast Neoplasms; Ovarian Neoplasms; Asthma; Lung Diseases, Obstructive
Cysteinyl leukotriene receptor 1 antagonist
Small molecule
Approved
OTHER; RESPIRATORY
ORAL
Inflammation; Anemia, Sickle Cell; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Acne Vulgaris; Idiopathic Pulmonary Fibrosis; Lung Neoplasms; Tobacco Use Disorder; Pulmonary Disease, Chronic Obstructive; Asthma
Arachidonate 5-lipoxygenase inhibitor
Small molecule
Approved
ENT; OTHER; PHARMACOLOGY; RESPIRATORY
ORAL
Appendicitis; Osteomyelitis; Mastitis; Bacterial Infections; Bronchitis, Chronic; Infections; Otitis Media; Pharyngitis; Pneumonia; Tonsillitis
Bacterial penicillin-binding protein inhibitor
Small molecule
Approved
OTHER; RESPIRATORY
INTRAPLEURAL
Carcinoma, Non-Small-Cell Lung; Osteoarthritis, Hip; Osteoarthritis, Knee; Radius Fractures; Pleural Effusion
Unknown
Small molecule
Approved
RESPIRATORY
ORAL
Osteomyelitis; HIV Infections; Tuberculosis, Pulmonary; Tuberculosis
Bacterial DNA-directed RNA polymerase inhibitor
Antibody
Approved
OTHER; RESPIRATORY
UNKNOWN
Hernias, Diaphragmatic, Congenital; Respiratory Syncytial Virus Infections; Bronchopulmonary Dysplasia; Respiratory Tract Diseases
Fusion glycoprotein F0 inhibitor
Small molecule
Approved
OTHER; RESPIRATORY
ORAL
Long QT Syndrome; Heart Failure; Arrhythmias, Cardiac; Atrial Fibrillation
HERG blocker
Small molecule
Approved
IMMUNE SYSTEM; OTHER; RESPIRATORY
ORAL
Lecithin Cholesterol Acyltransferase Deficiency; Carcinoma, Non-Small-Cell Lung; Common Cold; Conjunctivitis, Allergic; Dermatitis; Dermatitis, Atopic; Eczema; Pruritus; Rhinitis, Allergic, Perennial; Hypersensitivity; Rhinitis, Allergic, Seasonal; Urticaria
Histamine H1 receptor antagonist
Small molecule
Approved
OTHER; RESPIRATORY
INHALATION
Lung Neoplasms; Bronchiolitis Obliterans; Hypersensitivity; Respiratory Distress Syndrome; Severe Acute Respiratory Syndrome; Bronchiectasis; Bronchitis; Tobacco Use Disorder; Asthma; Bronchial Spasm; Bronchitis, Chronic; Emphysema; Pulmonary Disease, Chronic Obstructive
Beta-2 adrenergic receptor agonist
Small molecule
Approved
CARDIOVASCULAR; OTHER; RESPIRATORY
INHALATION; INTRAVENOUS; IV (INFUSION); SUBCUTANEOUS
Raynaud Disease; Diabetic Foot; Reperfusion Injury; Scleroderma, Systemic; Hernias, Diaphragmatic, Congenital; Ischemia; Peripheral Vascular Diseases; Persistent Fetal Circulation Syndrome; Pulmonary Disease, Chronic Obstructive; Respiratory Distress Syndrome; Familial Primary Pulmonary Hypertension; Idiopathic Pulmonary Fibrosis; Hypertension, Pulmonary; Pulmonary Arterial Hypertension; Thrombosis
Prostanoid IP receptor agonist
Enzyme
Approved
RESPIRATORY
UNKNOWN
Mucopolysaccharidosis I; Mucopolysaccharidoses
Dermatan sulfate hydrolytic enzyme
Antibody
Approved
RESPIRATORY
UNKNOWN
Colonic Neoplasms; Dermatitis, Atopic; Drug Hypersensitivity; Job Syndrome; Lupus Erythematosus, Systemic; Bronchitis; Eosinophilic Esophagitis; Food Hypersensitivity; Gastroenteritis; Hypersensitivity; Immune System Diseases; Milk Hypersensitivity; Nephritis, Interstitial; Pemphigoid, Bullous; Pulmonary Disease, Chronic Obstructive; Severe Acute Respiratory Syndrome; Sinusitis; Angioedema; Cystitis, Interstitial; Peanut Hypersensitivity; Rhinitis, Allergic, Seasonal; Asthma; Lung Diseases, Obstructive; Urticaria
Ig epsilon chain C region inhibitor
Small molecule
Approved
NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER; RESPIRATORY
ORAL
Head and Neck Neoplasms; Muscular Dystrophies; Astrocytoma; Glioblastoma; Heart Failure; Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cushing Syndrome; Dementia, Vascular; Diabetes Mellitus, Type 2; Eisenmenger Complex; Essential Hypertension; Gastroparesis; Hypertension; Multiple Myeloma; Obesity; Priapism; Scleroderma, Systemic; Stroke; Glucose Intolerance; Heart Defects, Congenital; Insulin Resistance; Lung Diseases, Interstitial; Muscular Dystrophy, Duchenne; Raynaud Disease; Transposition of Great Vessels; Erectile Dysfunction; Hypertension, Pulmonary; Prostatic Hyperplasia; Pulmonary Arterial Hypertension
Phosphodiesterase 5A inhibitor
Small molecule
Approved
OTHER; RESPIRATORY
INHALATION
Renal Insufficiency; Cystic Fibrosis; Neoplasms; Spinal Cord Injuries; Asthma; Bronchial Spasm; Bronchitis, Chronic; Emphysema; Lung Diseases, Obstructive; Pulmonary Disease, Chronic Obstructive
Muscarinic acetylcholine receptor M3 antagonist
Small molecule
Approved
IMMUNE SYSTEM; OTHER; RESPIRATORY
ORAL
Asthma; Maxillary Sinusitis; Otitis Media; Otitis Media, Suppurative; Pharyngitis; Scrub Typhus; Tonsillitis; Bacterial Infections; Infections; Pneumonia
Bacterial 70S ribosome inhibitor
Small molecule
Approved
OTHER; PEDIATRICS; RESPIRATORY
INHALATION; NASAL
Pulmonary Disease, Chronic Obstructive; Chronic Disease; Hypersensitivity; Severe Acute Respiratory Syndrome; Asthma; Lung Diseases, Obstructive; Nasal Obstruction; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal
Glucocorticoid receptor agonist
Small molecule
Approved
CARDIOVASCULAR; OTHER; RESPIRATORY
ORAL
Anemia, Sickle Cell; Altitude Sickness; Asthma; Hypoplastic Left Heart Syndrome; Severe Acute Respiratory Syndrome; Idiopathic Pulmonary Fibrosis; Vascular Diseases; Familial Primary Pulmonary Hypertension; Hypertension; Hypertension, Pulmonary; Pulmonary Arterial Hypertension
Endothelin receptor, ET-A/ET-B antagonist
Small molecule
Approved
IMMUNE SYSTEM; OTHER; RESPIRATORY
INJECTION
Renal Insufficiency, Chronic; Gram-Positive Bacterial Infections; Infections; Bacteremia; Pneumonia, Bacterial; Staphylococcal Skin Infections; Bacterial Infections
Unknown
Small molecule
Approved
OTHER; RESPIRATORY
INTRAVENOUS
Kidney Diseases; Meningitis; Pneumonia; Systemic Inflammatory Response Syndrome; Sepsis; Urinary Tract Infections; Infections; Pneumonia, Bacterial; Bacterial Infections
Unknown
Small molecule
Approved
RESPIRATORY
ORAL
Glioblastoma; Heart Failure; Idiopathic Pulmonary Fibrosis; Hernias, Diaphragmatic, Congenital; Hypertension, Pulmonary; Scleroderma, Systemic; Ulcer; Familial Primary Pulmonary Hypertension; Hypertension
Endothelin receptor, ET-A/ET-B antagonist
Small molecule
Approved
CANCER; OTHER; RESPIRATORY
ORAL
Breast Neoplasms; Colorectal Neoplasms; Diffuse Intrinsic Pontine Glioma; Glioblastoma; Kidney Diseases; Lung Neoplasms; Prostatic Neoplasms, Castration-Resistant; Adenocarcinoma; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Endometrial Neoplasms; Granuloma, Plasma Cell; Leukemia, Myeloid, Acute; Lymphoma, Large-Cell, Anaplastic; Multiple Myeloma; Neurofibromatosis 2; Stomach Neoplasms; Adenocarcinoma of Lung; Carcinoma, Non-Small-Cell Lung; Lymphoma, Large B-Cell, Diffuse; Neoplasms
ALK tyrosine kinase receptor inhibitor
Small molecule
Approved
RESPIRATORY
ORAL
Multiple Sclerosis; Alveolitis, Extrinsic Allergic; Bronchiolitis Obliterans; Burns; Cardiomyopathy, Hypertrophic; Glomerulosclerosis, Focal Segmental; Heart Failure; Leiomyoma; Liver Cirrhosis; Lung Diseases, Interstitial; Nephrotic Syndrome; Neurofibromatosis 1; Pneumoconiosis; Proteinuria; Pulmonary Fibrosis; Radiation Pneumonitis; Renal Insufficiency; Renal Insufficiency, Chronic; Scleroderma, Systemic; Severe Acute Respiratory Syndrome; Diabetic Foot; Keloid; Pneumonia; Idiopathic Pulmonary Fibrosis; Immune System Diseases
Unknown
Small molecule
Approved
RESPIRATORY
ORAL
Tuberculosis
ATP synthase inhibitor