DrugMapper


Display Options: Drug type Therapeutic Area Route of administration Mechanism of Action Indication Status		Total: 50


Small molecule Approved DENTISTRY; NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER BUCCAL; ORAL; RECTAL; TOPICAL Attention Deficit Disorder with Hyperactivity; Complex Regional Pain Syndromes; Humeral Fractures; Morton Neuroma; Parathyroid Neoplasms; Skin Neoplasms; Spinal Fractures; Tinnitus; Brain Neoplasms; Carcinoma, Squamous Cell; Glioblastoma; Glycogen Storage Disease Type II; Hypertension, Pulmonary; Keratosis, Actinic; Lung Neoplasms; Neuroma; Premature Birth; Thromboembolism; Anus Diseases; Anxiety; Carcinoma; Cocaine-Related Disorders; Cognitive Dysfunction; Cystitis, Interstitial; Diabetic Neuropathies; Dysmenorrhea; Heart Diseases; Infertility; Irritable Bowel Syndrome; Leiomyoma; Macular Degeneration; Myofascial Pain Syndromes; Neoplasms; Osteoarthritis, Knee; Renal Colic; Rib Fractures; Scleroderma, Localized; Severe Acute Respiratory Syndrome; Shoulder Impingement Syndrome; Shoulder Pain; Skin Diseases; Temporomandibular Joint Disorders; Trigeminal Neuralgia; Urinary Incontinence; Urinary Tract Infections; Breast Neoplasms; Carpal Tunnel Syndrome; Chronic Pain; Colorectal Neoplasms; Common Cold; Cough; Dysuria; Fibromyalgia; Headache; Heart Arrest; Hemorrhage; Ileus; Low Back Pain; Migraine Disorders; Muscular Diseases; Nutrition Disorders; Obesity; Obesity, Morbid; Osteoporosis, Postmenopausal; Paget Disease, Extramammary; Parathyroid Diseases; Periarthritis; Peripheral Nervous System Diseases; Pharyngitis; Pre-Eclampsia; Pregnancy; Pulpitis; Scoliosis; Shock, Septic; Sinusitis; Stomatitis; Stroke; Tennis Elbow; Urinary Bladder, Overactive; Uterine Cervical Dysplasia; Wounds and Injuries; Arrhythmias, Cardiac; Arthritis; Back Pain; Burns; Bursitis; Hemorrhoids; Inflammation; Insect Bites and Stings; Muscle Cramp; Myalgia; Neuralgia; Neuralgia, Postherpetic; Osteoarthritis; Pain; Premature Ejaculation; Pruritus; Rectal Diseases; Sprains and Strains; Sunburn; Tendinopathy; Urethritis Sodium channel alpha subunit blocker

Small molecule

Approved

DENTISTRY; NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER

BUCCAL; ORAL; RECTAL; TOPICAL

Attention Deficit Disorder with Hyperactivity; Complex Regional Pain Syndromes; Humeral Fractures; Morton Neuroma; Parathyroid Neoplasms; Skin Neoplasms; Spinal Fractures; Tinnitus; Brain Neoplasms; Carcinoma, Squamous Cell; Glioblastoma; Glycogen Storage Disease Type II; Hypertension, Pulmonary; Keratosis, Actinic; Lung Neoplasms; Neuroma; Premature Birth; Thromboembolism; Anus Diseases; Anxiety; Carcinoma; Cocaine-Related Disorders; Cognitive Dysfunction; Cystitis, Interstitial; Diabetic Neuropathies; Dysmenorrhea; Heart Diseases; Infertility; Irritable Bowel Syndrome; Leiomyoma; Macular Degeneration; Myofascial Pain Syndromes; Neoplasms; Osteoarthritis, Knee; Renal Colic; Rib Fractures; Scleroderma, Localized; Severe Acute Respiratory Syndrome; Shoulder Impingement Syndrome; Shoulder Pain; Skin Diseases; Temporomandibular Joint Disorders; Trigeminal Neuralgia; Urinary Incontinence; Urinary Tract Infections; Breast Neoplasms; Carpal Tunnel Syndrome; Chronic Pain; Colorectal Neoplasms; Common Cold; Cough; Dysuria; Fibromyalgia; Headache; Heart Arrest; Hemorrhage; Ileus; Low Back Pain; Migraine Disorders; Muscular Diseases; Nutrition Disorders; Obesity; Obesity, Morbid; Osteoporosis, Postmenopausal; Paget Disease, Extramammary; Parathyroid Diseases; Periarthritis; Peripheral Nervous System Diseases; Pharyngitis; Pre-Eclampsia; Pregnancy; Pulpitis; Scoliosis; Shock, Septic; Sinusitis; Stomatitis; Stroke; Tennis Elbow; Urinary Bladder, Overactive; Uterine Cervical Dysplasia; Wounds and Injuries; Arrhythmias, Cardiac; Arthritis; Back Pain; Burns; Bursitis; Hemorrhoids; Inflammation; Insect Bites and Stings; Muscle Cramp; Myalgia; Neuralgia; Neuralgia, Postherpetic; Osteoarthritis; Pain; Premature Ejaculation; Pruritus; Rectal Diseases; Sprains and Strains; Sunburn; Tendinopathy; Urethritis

Sodium channel alpha subunit blocker


Small molecule Approved CANCER; NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER BUCCAL; SUBLINGUAL; TRANSDERMAL Opioid-Related Disorders; Respiratory Distress Syndrome; Brain Injuries; Breast Neoplasms; Bronchial Spasm; Delirium; Fractures, Bone; Hypospadias; Hypotension; Irritable Bowel Syndrome; Pulpitis; Scoliosis; Subarachnoid Hemorrhage; Abscess; Adenoma; Diabetic Neuropathies; Liver Diseases; Low Back Pain; Neoplasm Metastasis; Obesity; Obesity, Morbid; Osteoarthritis; Pancreatic Neoplasms; Renal Insufficiency, Chronic; Respiratory Insufficiency; Sleep Apnea, Obstructive; Stomach Neoplasms; Acute Pain; Cancer Pain; Chronic Pain; Migraine Disorders; Neoplasms; Pain Mu opioid receptor agonist

Small molecule

Approved

CANCER; NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER

BUCCAL; SUBLINGUAL; TRANSDERMAL

Opioid-Related Disorders; Respiratory Distress Syndrome; Brain Injuries; Breast Neoplasms; Bronchial Spasm; Delirium; Fractures, Bone; Hypospadias; Hypotension; Irritable Bowel Syndrome; Pulpitis; Scoliosis; Subarachnoid Hemorrhage; Abscess; Adenoma; Diabetic Neuropathies; Liver Diseases; Low Back Pain; Neoplasm Metastasis; Obesity; Obesity, Morbid; Osteoarthritis; Pancreatic Neoplasms; Renal Insufficiency, Chronic; Respiratory Insufficiency; Sleep Apnea, Obstructive; Stomach Neoplasms; Acute Pain; Cancer Pain; Chronic Pain; Migraine Disorders; Neoplasms; Pain

Mu opioid receptor agonist


Small molecule Approved NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER; PEDIATRICS INTRAVENOUS; ORAL Hepatitis B, Chronic; Cocaine-Related Disorders; Epilepsy, Reflex; HIV Infections; Nausea; Anxiety; Dementia; Depressive Disorder; Schizophrenia; Bipolar Disorder; Epilepsies, Partial; Epilepsy; Glossopharyngeal Nerve Diseases; Seizures; Trigeminal Neuralgia Sodium channel alpha subunit blocker


Small molecule Approved EMERGENCY MEDICINE; NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER INJECTION Neuralgia; Aortic Coarctation; Brain Neoplasms; HIV Infections; Prostatic Neoplasms, Castration-Resistant; Sinusitis; Vasospasm, Intracranial; Abdominal Pain; Appendicitis; Blepharoptosis; Blood Coagulation Disorders; Cleft Palate; Dupuytren Contracture; Fasciitis, Plantar; Femoral Neck Fractures; Headache; Hemorrhage; Hernia, Umbilical; Hip Fractures; Hypospadias; Hypotension; Lacrimal Apparatus Diseases; Low Back Pain; Lung Neoplasms; Mucositis; Osteoarthritis, Hip; Osteoarthritis, Knee; Pregnancy; Pulpitis; Rib Fractures; Rotator Cuff Injuries; Sarcoma; Shoulder Pain; Spinal Stenosis; Ankle Fractures; Breast Neoplasms; Breech Presentation; Carcinoma, Non-Small-Cell Lung; Chronic Pain; Cough; Fractures, Bone; Genital Neoplasms, Female; Hallux Valgus; Hemorrhoids; Hernia, Inguinal; Ileus; Liver Diseases; Migraine Disorders; Neoplasms; Osteoarthritis; Pancreatic Neoplasms; Pancreatitis, Chronic; Peritoneal Neoplasms; Postoperative Complications; Postoperative Nausea and Vomiting; Radiculopathy; Toothache; Urethral Stricture; Wounds and Injuries; Hernia; Pain Sodium channel protein type IV alpha subunit blocker

Small molecule

Approved

EMERGENCY MEDICINE; NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER

INJECTION

Neuralgia; Aortic Coarctation; Brain Neoplasms; HIV Infections; Prostatic Neoplasms, Castration-Resistant; Sinusitis; Vasospasm, Intracranial; Abdominal Pain; Appendicitis; Blepharoptosis; Blood Coagulation Disorders; Cleft Palate; Dupuytren Contracture; Fasciitis, Plantar; Femoral Neck Fractures; Headache; Hemorrhage; Hernia, Umbilical; Hip Fractures; Hypospadias; Hypotension; Lacrimal Apparatus Diseases; Low Back Pain; Lung Neoplasms; Mucositis; Osteoarthritis, Hip; Osteoarthritis, Knee; Pregnancy; Pulpitis; Rib Fractures; Rotator Cuff Injuries; Sarcoma; Shoulder Pain; Spinal Stenosis; Ankle Fractures; Breast Neoplasms; Breech Presentation; Carcinoma, Non-Small-Cell Lung; Chronic Pain; Cough; Fractures, Bone; Genital Neoplasms, Female; Hallux Valgus; Hemorrhoids; Hernia, Inguinal; Ileus; Liver Diseases; Migraine Disorders; Neoplasms; Osteoarthritis; Pancreatic Neoplasms; Pancreatitis, Chronic; Peritoneal Neoplasms; Postoperative Complications; Postoperative Nausea and Vomiting; Radiculopathy; Toothache; Urethral Stricture; Wounds and Injuries; Hernia; Pain

Sodium channel protein type IV alpha subunit blocker


Small molecule Approved NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER ORAL Burning Mouth Syndrome; Neuralgia; Marijuana Abuse; REM Sleep Behavior Disorder; Anxiety; Dementia; Depressive Disorder; Epilepsia Partialis Continua; Epilepsy, Tonic-Clonic; Pain; Schizophrenia; Status Epilepticus; Epilepsy; Panic Disorder; Seizures GABA-A receptor; anion channel positive allosteric modulator


Small molecule Approved NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER ORAL Alzheimer Disease; Urinary Bladder Neoplasms; Astrocytoma; Burkitt Lymphoma; Carcinoma, Non-Small-Cell Lung; Central Nervous System Neoplasms; Colorectal Neoplasms; Lung Neoplasms; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Medulloblastoma; Nasopharyngeal Neoplasms; Neoplasms; Ovarian Neoplasms; Sarcoma; Shock; Wounds and Injuries; Alopecia; Brain Neoplasms; Breast Neoplasms; Carcinoma, Squamous Cell; Glioblastoma; Glioma; Head and Neck Neoplasms; HIV Infections; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Lymphoma; Melanoma; Muscular Atrophy, Spinal; Myelodysplastic Syndromes; Neuralgia; Pancreatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Retinitis Pigmentosa; Small Cell Lung Carcinoma; Supranuclear Palsy, Progressive; Thyroid Neoplasms; Anxiety; Dementia; Depressive Disorder; Paraparesis, Tropical Spastic; Schizophrenia; Status Epilepticus; Anorexia; Bipolar Disorder; Epilepsy; Epilepsy, Absence; Epilepsy, Complex Partial; Migraine Disorders; Mitochondrial Diseases; Seizures; Vomiting Succinate semialdehyde dehydrogenase inhibitor

Small molecule

Approved

NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER

ORAL

Alzheimer Disease; Urinary Bladder Neoplasms; Astrocytoma; Burkitt Lymphoma; Carcinoma, Non-Small-Cell Lung; Central Nervous System Neoplasms; Colorectal Neoplasms; Lung Neoplasms; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Medulloblastoma; Nasopharyngeal Neoplasms; Neoplasms; Ovarian Neoplasms; Sarcoma; Shock; Wounds and Injuries; Alopecia; Brain Neoplasms; Breast Neoplasms; Carcinoma, Squamous Cell; Glioblastoma; Glioma; Head and Neck Neoplasms; HIV Infections; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Lymphoma; Melanoma; Muscular Atrophy, Spinal; Myelodysplastic Syndromes; Neuralgia; Pancreatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Retinitis Pigmentosa; Small Cell Lung Carcinoma; Supranuclear Palsy, Progressive; Thyroid Neoplasms; Anxiety; Dementia; Depressive Disorder; Paraparesis, Tropical Spastic; Schizophrenia; Status Epilepticus; Anorexia; Bipolar Disorder; Epilepsy; Epilepsy, Absence; Epilepsy, Complex Partial; Migraine Disorders; Mitochondrial Diseases; Seizures; Vomiting

Succinate semialdehyde dehydrogenase inhibitor


Small molecule Approved NEUROLOGY DRUGS & NERVOUS SYSTEM INTRAMUSCULAR Bulimia; Alcohol Drinking; Child Development Disorders, Pervasive; Dermatitis, Atopic; Psoriasis; Schizophrenia; Alcohol-Related Disorders; Amphetamine-Related Disorders; Breast Neoplasms; Colitis, Ulcerative; Coronavirus Infections; Crohn Disease; Cystitis, Interstitial; Depressive Disorder, Major; Diabetic Neuropathies; Dry Eye Syndromes; Fibromyalgia; Low Back Pain; Marijuana Abuse; Migraine Disorders; Obsessive-Compulsive Disorder; Respiratory Distress Syndrome; Severe Acute Respiratory Syndrome; Trichotillomania; Borderline Personality Disorder; Chronic Pain; Cocaine-Related Disorders; Depressive Disorder; Endometriosis; Gambling; Heroin Dependence; HIV Infections; Multiple Sclerosis; Obesity; Opioid-Related Disorders; Pain; Stress Disorders, Post-Traumatic; Substance-Related Disorders; Tobacco Use Disorder; Alcoholism Opioid receptors; mu/kappa/delta antagonist

Small molecule

Approved

NEUROLOGY DRUGS & NERVOUS SYSTEM

INTRAMUSCULAR

Bulimia; Alcohol Drinking; Child Development Disorders, Pervasive; Dermatitis, Atopic; Psoriasis; Schizophrenia; Alcohol-Related Disorders; Amphetamine-Related Disorders; Breast Neoplasms; Colitis, Ulcerative; Coronavirus Infections; Crohn Disease; Cystitis, Interstitial; Depressive Disorder, Major; Diabetic Neuropathies; Dry Eye Syndromes; Fibromyalgia; Low Back Pain; Marijuana Abuse; Migraine Disorders; Obsessive-Compulsive Disorder; Respiratory Distress Syndrome; Severe Acute Respiratory Syndrome; Trichotillomania; Borderline Personality Disorder; Chronic Pain; Cocaine-Related Disorders; Depressive Disorder; Endometriosis; Gambling; Heroin Dependence; HIV Infections; Multiple Sclerosis; Obesity; Opioid-Related Disorders; Pain; Stress Disorders, Post-Traumatic; Substance-Related Disorders; Tobacco Use Disorder; Alcoholism

Opioid receptors; mu/kappa/delta antagonist


Small molecule Approved IMMUNE SYSTEM; NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER; PEDIATRICS ORAL Alopecia; Child Development Disorders, Pervasive; Premature Birth; Psychotic Disorders; Abortion, Spontaneous; Anemia, Sickle Cell; Breast Neoplasms; Hyperemesis Gravidarum; Intervertebral Disc Displacement; Low Back Pain; Marijuana Abuse; Mucositis; Multiple Sclerosis; Neoplasms; Opioid-Related Disorders; Paget Disease, Extramammary; Postoperative Complications; Prostatic Neoplasms, Castration-Resistant; Rotator Cuff Injuries; Substance-Related Disorders; Substance Withdrawal Syndrome; Tinnitus; Tobacco Use Disorder; Urinary Bladder Neoplasms; Wounds and Injuries; Alcohol Drinking; Alcoholism; Anxiety; Azoospermia; Carpal Tunnel Syndrome; Chronic Pain; Delirium; Dementia; Depressive Disorder; Diabetic Neuropathies; Dyspepsia; Epilepsies, Partial; Fibromyalgia; Head and Neck Neoplasms; Herpes Zoster; Hot Flashes; Intervertebral Disc Degeneration; Liver Cirrhosis; Neuralgia; Oropharyngeal Neoplasms; Pain; Pelvic Organ Prolapse; Postoperative Nausea and Vomiting; Pruritus; Schizophrenia; Scoliosis; Sleep Initiation and Maintenance Disorders; Tremor; Vomiting; Epilepsy; Neuralgia, Postherpetic; Restless Legs Syndrome; Seizures Voltage-gated calcium channel modulator

Small molecule

Approved

IMMUNE SYSTEM; NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER; PEDIATRICS

ORAL

Alopecia; Child Development Disorders, Pervasive; Premature Birth; Psychotic Disorders; Abortion, Spontaneous; Anemia, Sickle Cell; Breast Neoplasms; Hyperemesis Gravidarum; Intervertebral Disc Displacement; Low Back Pain; Marijuana Abuse; Mucositis; Multiple Sclerosis; Neoplasms; Opioid-Related Disorders; Paget Disease, Extramammary; Postoperative Complications; Prostatic Neoplasms, Castration-Resistant; Rotator Cuff Injuries; Substance-Related Disorders; Substance Withdrawal Syndrome; Tinnitus; Tobacco Use Disorder; Urinary Bladder Neoplasms; Wounds and Injuries; Alcohol Drinking; Alcoholism; Anxiety; Azoospermia; Carpal Tunnel Syndrome; Chronic Pain; Delirium; Dementia; Depressive Disorder; Diabetic Neuropathies; Dyspepsia; Epilepsies, Partial; Fibromyalgia; Head and Neck Neoplasms; Herpes Zoster; Hot Flashes; Intervertebral Disc Degeneration; Liver Cirrhosis; Neuralgia; Oropharyngeal Neoplasms; Pain; Pelvic Organ Prolapse; Postoperative Nausea and Vomiting; Pruritus; Schizophrenia; Scoliosis; Sleep Initiation and Maintenance Disorders; Tremor; Vomiting; Epilepsy; Neuralgia, Postherpetic; Restless Legs Syndrome; Seizures

Voltage-gated calcium channel modulator


Protein Approved NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER SUBCUTANEOUS Cardiomyopathies; Coronavirus Infections; Severe Acute Respiratory Syndrome; HIV Infections; Multiple Sclerosis, Relapsing-Remitting; Multiple Sclerosis Interferon alpha/beta receptor agonist


Small molecule Approved NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER ORAL HIV Infections; Lecithin Cholesterol Acyltransferase Deficiency; Mental Disorders; Alcoholism; Cocaine-Related Disorders; Cognitive Dysfunction; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Neuralgia, Postherpetic; Neurofibromatosis 1; Opioid-Related Disorders; Substance-Related Disorders; Anxiety; Dementia; Epilepsy, Absence; Feeding and Eating Disorders; Mood Disorders; Obesity; Pain; Peripheral Nervous System Diseases; Schizophrenia; Bipolar Disorder; Depressive Disorder; Epilepsies, Partial; Epilepsy; Epilepsy, Tonic-Clonic; Lennox Gastaut Syndrome; Seizures Sodium channel alpha subunit blocker

Small molecule

Approved

NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER

ORAL

HIV Infections; Lecithin Cholesterol Acyltransferase Deficiency; Mental Disorders; Alcoholism; Cocaine-Related Disorders; Cognitive Dysfunction; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Neuralgia, Postherpetic; Neurofibromatosis 1; Opioid-Related Disorders; Substance-Related Disorders; Anxiety; Dementia; Epilepsy, Absence; Feeding and Eating Disorders; Mood Disorders; Obesity; Pain; Peripheral Nervous System Diseases; Schizophrenia; Bipolar Disorder; Depressive Disorder; Epilepsies, Partial; Epilepsy; Epilepsy, Tonic-Clonic; Lennox Gastaut Syndrome; Seizures

Sodium channel alpha subunit blocker


Small molecule Approved NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER ORAL Breast Neoplasms; Stress Disorders, Post-Traumatic; Alzheimer Disease; Bipolar Disorder; Cerebellar Ataxia; Child Development Disorders, Pervasive; Depressive Disorder; Depressive Disorder, Major; Melanoma; Multiple Sclerosis; Multiple Sclerosis, Chronic Progressive; Muscular Atrophy, Spinal; Obsessive-Compulsive Disorder; Peripheral Nervous System Diseases; Spinal Cord Injuries; Huntington Disease; Multiple System Atrophy; Spinal Cord Diseases; Spinocerebellar Ataxias; Supranuclear Palsy, Progressive; Amyotrophic Lateral Sclerosis Sodium channel alpha subunit blocker

Small molecule

Approved

NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER

ORAL

Breast Neoplasms; Stress Disorders, Post-Traumatic; Alzheimer Disease; Bipolar Disorder; Cerebellar Ataxia; Child Development Disorders, Pervasive; Depressive Disorder; Depressive Disorder, Major; Melanoma; Multiple Sclerosis; Multiple Sclerosis, Chronic Progressive; Muscular Atrophy, Spinal; Obsessive-Compulsive Disorder; Peripheral Nervous System Diseases; Spinal Cord Injuries; Huntington Disease; Multiple System Atrophy; Spinal Cord Diseases; Spinocerebellar Ataxias; Supranuclear Palsy, Progressive; Amyotrophic Lateral Sclerosis

Sodium channel alpha subunit blocker


Small molecule Approved NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER; PEDIATRICS ORAL Feeding and Eating Disorders; Bulimia Nervosa; Cognitive Dysfunction; Hernias, Diaphragmatic, Congenital; Liver Diseases; Alcohol Drinking; Amphetamine-Related Disorders; Brain Ischemia; Diabetes Mellitus; Marijuana Abuse; Multiple Sclerosis; Parkinson Disease; Sciatica; Stress Disorders, Post-Traumatic; Alcoholism; Anxiety; Bipolar Disorder; Bulimia; Cocaine-Related Disorders; Dementia; Depressive Disorder; Diabetes Mellitus, Type 2; Epilepsies, Partial; Epilepsy, Tonic-Clonic; Essential Tremor; Gambling; Headache; Hyperlipidemias; Hypertension; Hypertriglyceridemia; Metabolic Syndrome; Obesity; Obsessive-Compulsive Disorder; Pain; Prader-Willi Syndrome; Schizophrenia; Smoking Cessation; Tobacco Use Disorder; Tourette Syndrome; Epilepsy; Lennox Gastaut Syndrome; Migraine Disorders; Seizures Carbonic anhydrase II inhibitor

Small molecule

Approved

NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER; PEDIATRICS

ORAL

Feeding and Eating Disorders; Bulimia Nervosa; Cognitive Dysfunction; Hernias, Diaphragmatic, Congenital; Liver Diseases; Alcohol Drinking; Amphetamine-Related Disorders; Brain Ischemia; Diabetes Mellitus; Marijuana Abuse; Multiple Sclerosis; Parkinson Disease; Sciatica; Stress Disorders, Post-Traumatic; Alcoholism; Anxiety; Bipolar Disorder; Bulimia; Cocaine-Related Disorders; Dementia; Depressive Disorder; Diabetes Mellitus, Type 2; Epilepsies, Partial; Epilepsy, Tonic-Clonic; Essential Tremor; Gambling; Headache; Hyperlipidemias; Hypertension; Hypertriglyceridemia; Metabolic Syndrome; Obesity; Obsessive-Compulsive Disorder; Pain; Prader-Willi Syndrome; Schizophrenia; Smoking Cessation; Tobacco Use Disorder; Tourette Syndrome; Epilepsy; Lennox Gastaut Syndrome; Migraine Disorders; Seizures

Carbonic anhydrase II inhibitor


Small molecule Approved GASTROINTESTINAL; NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER INJECTION; INTRAVENOUS Osteomyelitis; Gram-Negative Bacterial Infections; Pancreatitis; Respiratory Insufficiency; Communicable Diseases; Tuberculosis; Tuberculosis, Pulmonary; Enterobacteriaceae Infections; Neonatal Sepsis; Pneumonia; Pneumonia, Bacterial; Pneumonia, Ventilator-Associated; Pyelonephritis; Sepsis; Shock, Septic; Bacteremia; Bacterial Infections; Infections; Intraabdominal Infections; Meningitis; Meningitis, Bacterial; Urinary Tract Infections Bacterial penicillin-binding protein inhibitor

Small molecule

Approved

GASTROINTESTINAL; NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER

INJECTION; INTRAVENOUS

Osteomyelitis; Gram-Negative Bacterial Infections; Pancreatitis; Respiratory Insufficiency; Communicable Diseases; Tuberculosis; Tuberculosis, Pulmonary; Enterobacteriaceae Infections; Neonatal Sepsis; Pneumonia; Pneumonia, Bacterial; Pneumonia, Ventilator-Associated; Pyelonephritis; Sepsis; Shock, Septic; Bacteremia; Bacterial Infections; Infections; Intraabdominal Infections; Meningitis; Meningitis, Bacterial; Urinary Tract Infections

Bacterial penicillin-binding protein inhibitor


Protein Approved NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER UNKNOWN Stroke; Alzheimer Disease; Asthma; Colitis, Ulcerative; Crohn Disease; Multiple Organ Failure; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating; Pulmonary Disease, Chronic Obstructive; Hepatitis C; Multiple Sclerosis, Relapsing-Remitting; Respiratory Distress Syndrome; Severe Acute Respiratory Syndrome; Multiple Sclerosis Interferon alpha/beta receptor agonist

Protein

Approved

NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER

UNKNOWN

Stroke; Alzheimer Disease; Asthma; Colitis, Ulcerative; Crohn Disease; Multiple Organ Failure; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating; Pulmonary Disease, Chronic Obstructive; Hepatitis C; Multiple Sclerosis, Relapsing-Remitting; Respiratory Distress Syndrome; Severe Acute Respiratory Syndrome; Multiple Sclerosis

Interferon alpha/beta receptor agonist


Small molecule Approved NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER NASAL; ORAL Migraine Disorders Serotonin 1b (5-HT1b) receptor agonist


Small molecule Approved NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER ORAL Cocaine-Related Disorders; Neuroblastoma; Alcoholism; Brain Injuries; Gambling; Obsessive-Compulsive Disorder; Pick Disease of the Brain; Schizophrenia; Tobacco Use Disorder; Liver Failure; Parkinson Disease Catechol O-methyltransferase inhibitor


Small molecule Approved NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER INTRAVENOUS; ORAL Aphasia; Canavan Disease; Essential Tremor; Stroke; Alzheimer Disease; Anemia, Sickle Cell; Bipolar Disorder; Brain Neoplasms; Cocaine-Related Disorders; Cognitive Dysfunction; Dyskinesia, Drug-Induced; Epilepsy, Absence; Epilepsy, Reflex; Glioblastoma; Glioma; Leukemia, Myeloid, Acute; Neuralgia, Postherpetic; Neuroblastoma; Obsessive-Compulsive Disorder; Opioid-Related Disorders; Parkinson Disease; Polyneuropathies; Psychotic Disorders; Restless Legs Syndrome; Stress Disorders, Post-Traumatic; Torticollis; Alcoholism; Anxiety; Dementia; Depressive Disorder; Epilepsies, Partial; Movement Disorders; Panic Disorder; Schizophrenia; Status Epilepticus; Subarachnoid Hemorrhage; Substance Withdrawal Syndrome; Epilepsy; Epilepsy, Tonic-Clonic; Seizures Synaptic vesicle glycoprotein 2A modulator

Small molecule

Approved

NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER

INTRAVENOUS; ORAL

Aphasia; Canavan Disease; Essential Tremor; Stroke; Alzheimer Disease; Anemia, Sickle Cell; Bipolar Disorder; Brain Neoplasms; Cocaine-Related Disorders; Cognitive Dysfunction; Dyskinesia, Drug-Induced; Epilepsy, Absence; Epilepsy, Reflex; Glioblastoma; Glioma; Leukemia, Myeloid, Acute; Neuralgia, Postherpetic; Neuroblastoma; Obsessive-Compulsive Disorder; Opioid-Related Disorders; Parkinson Disease; Polyneuropathies; Psychotic Disorders; Restless Legs Syndrome; Stress Disorders, Post-Traumatic; Torticollis; Alcoholism; Anxiety; Dementia; Depressive Disorder; Epilepsies, Partial; Movement Disorders; Panic Disorder; Schizophrenia; Status Epilepticus; Subarachnoid Hemorrhage; Substance Withdrawal Syndrome; Epilepsy; Epilepsy, Tonic-Clonic; Seizures

Synaptic vesicle glycoprotein 2A modulator


Small molecule Approved NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER ORAL Amphetamine-Related Disorders; Gastrointestinal Stromal Tumors; Epilepsy; Obesity; Cocaine-Related Disorders; Parkinson Disease Catechol O-methyltransferase inhibitor


Small molecule Approved NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER; PREGNANCY AND GYNECOLOGY ORAL; VAGINAL Atrophy; Menopause Estrogen receptor agonist


Small molecule Approved NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER ORAL Anxiety; Dementia; Depressive Disorder; Schizophrenia; Sleep Initiation and Maintenance Disorders GABA A receptor alpha-1/beta-1/gamma-2 positive allosteric modulator


Small molecule Approved NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER TRANSDERMAL Amphetamine-Related Disorders; Cocaine-Related Disorders; Down Syndrome; Substance-Related Disorders; Anxiety; Brain Injuries; Cognitive Dysfunction; Delirium; Dementia, Vascular; Depressive Disorder; Neurobehavioral Manifestations; Schizophrenia; Supranuclear Palsy, Progressive; Alzheimer Disease; Dementia; Parkinson Disease Cholinesterases; ACHE & BCHE inhibitor

Small molecule

Approved

NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER

TRANSDERMAL

Amphetamine-Related Disorders; Cocaine-Related Disorders; Down Syndrome; Substance-Related Disorders; Anxiety; Brain Injuries; Cognitive Dysfunction; Delirium; Dementia, Vascular; Depressive Disorder; Neurobehavioral Manifestations; Schizophrenia; Supranuclear Palsy, Progressive; Alzheimer Disease; Dementia; Parkinson Disease

Cholinesterases; ACHE & BCHE inhibitor


Small molecule Approved NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER ORAL Cocaine-Related Disorders; Hearing Loss, Noise-Induced; Tobacco Use Disorder; Essential Tremor; Hearing Loss; Migraine Disorders; Obesity; Parkinson Disease; Alcoholism; Epilepsy, Complex Partial; Feeding and Eating Disorders; Psychotic Disorders; Schizophrenia; Smoking Cessation; Weight Gain; Epilepsy; Seizures Sodium channel alpha subunit blocker

Small molecule

Approved

NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER

ORAL

Cocaine-Related Disorders; Hearing Loss, Noise-Induced; Tobacco Use Disorder; Essential Tremor; Hearing Loss; Migraine Disorders; Obesity; Parkinson Disease; Alcoholism; Epilepsy, Complex Partial; Feeding and Eating Disorders; Psychotic Disorders; Schizophrenia; Smoking Cessation; Weight Gain; Epilepsy; Seizures

Sodium channel alpha subunit blocker


Small molecule Approved NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER; PEDIATRICS ORAL Neoplasms; Multiple Sclerosis; Aggression; Anxiety; Dementia; Depressive Disorder; Epilepsies, Partial; Neuralgia; Psychomotor Agitation; Schizophrenia; Epilepsy; Seizures Sodium channel alpha subunit blocker


Antibody Approved CANCER; NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER INJECTION; INTRAVENOUS Neoplasms, Neuroepithelial; Anemia; Arthritis, Rheumatoid; Fallopian Tube Neoplasms; Fanconi Anemia; Kidney Diseases; Leukemia, Prolymphocytic, T-Cell; Lymphohistiocytosis, Hemophagocytic; Lymphoma, Non-Hodgkin; Multiple Myeloma; Neuroblastoma; Ovarian Neoplasms; Peritoneal Neoplasms; Renal Insufficiency; Vasculitis; Anemia, Aplastic; Anemia, Hemolytic, Autoimmune; beta-Thalassemia; Crohn Disease; Diabetes Mellitus, Type 1; Graft vs Host Disease; Granulomatous Disease, Chronic; Hematologic Neoplasms; Hemoglobinopathies; Histiocytosis; Hodgkin Disease; Kidney Neoplasms; Leukemia, Biphenotypic, Acute; Leukemia, Erythroblastic, Acute; Leukemia, Large Granular Lymphocytic; Leukemia, Lymphoid; Leukemia, Prolymphocytic; Liver Diseases; Lymphoma, Large B-Cell, Diffuse; Mycosis Fungoides; Myeloproliferative Disorders; Myositis, Inclusion Body; Neoplasms; Osteopetrosis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Purpura, Thrombocytopenic, Idiopathic; Renal Insufficiency, Chronic; Severe Combined Immunodeficiency; Sezary Syndrome; Thalassemia; Waldenstrom Macroglobulinemia; Anemia, Sickle Cell; Granuloma, Lethal Midline; Immunoblastic Lymphadenopathy; Leukemia; Leukemia, Myeloid, Acute; Lymphoma; Lymphoma, T-Cell, Peripheral; Multiple Sclerosis, Relapsing-Remitting; Myelodysplastic Syndromes; Immune System Diseases; Leukemia, Lymphocytic, Chronic, B-Cell; Multiple Sclerosis CAMPATH-1 antigen inhibitor

Antibody

Approved

CANCER; NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER

INJECTION; INTRAVENOUS

Neoplasms, Neuroepithelial; Anemia; Arthritis, Rheumatoid; Fallopian Tube Neoplasms; Fanconi Anemia; Kidney Diseases; Leukemia, Prolymphocytic, T-Cell; Lymphohistiocytosis, Hemophagocytic; Lymphoma, Non-Hodgkin; Multiple Myeloma; Neuroblastoma; Ovarian Neoplasms; Peritoneal Neoplasms; Renal Insufficiency; Vasculitis; Anemia, Aplastic; Anemia, Hemolytic, Autoimmune; beta-Thalassemia; Crohn Disease; Diabetes Mellitus, Type 1; Graft vs Host Disease; Granulomatous Disease, Chronic; Hematologic Neoplasms; Hemoglobinopathies; Histiocytosis; Hodgkin Disease; Kidney Neoplasms; Leukemia, Biphenotypic, Acute; Leukemia, Erythroblastic, Acute; Leukemia, Large Granular Lymphocytic; Leukemia, Lymphoid; Leukemia, Prolymphocytic; Liver Diseases; Lymphoma, Large B-Cell, Diffuse; Mycosis Fungoides; Myeloproliferative Disorders; Myositis, Inclusion Body; Neoplasms; Osteopetrosis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Purpura, Thrombocytopenic, Idiopathic; Renal Insufficiency, Chronic; Severe Combined Immunodeficiency; Sezary Syndrome; Thalassemia; Waldenstrom Macroglobulinemia; Anemia, Sickle Cell; Granuloma, Lethal Midline; Immunoblastic Lymphadenopathy; Leukemia; Leukemia, Myeloid, Acute; Lymphoma; Lymphoma, T-Cell, Peripheral; Multiple Sclerosis, Relapsing-Remitting; Myelodysplastic Syndromes; Immune System Diseases; Leukemia, Lymphocytic, Chronic, B-Cell; Multiple Sclerosis

CAMPATH-1 antigen inhibitor


Small molecule Approved NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER; RESPIRATORY ORAL Head and Neck Neoplasms; Muscular Dystrophies; Astrocytoma; Glioblastoma; Heart Failure; Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cushing Syndrome; Dementia, Vascular; Diabetes Mellitus, Type 2; Eisenmenger Complex; Essential Hypertension; Gastroparesis; Hypertension; Multiple Myeloma; Obesity; Priapism; Scleroderma, Systemic; Stroke; Glucose Intolerance; Heart Defects, Congenital; Insulin Resistance; Lung Diseases, Interstitial; Muscular Dystrophy, Duchenne; Raynaud Disease; Transposition of Great Vessels; Erectile Dysfunction; Hypertension, Pulmonary; Prostatic Hyperplasia; Pulmonary Arterial Hypertension Phosphodiesterase 5A inhibitor

Small molecule

Approved

NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER; RESPIRATORY

ORAL

Head and Neck Neoplasms; Muscular Dystrophies; Astrocytoma; Glioblastoma; Heart Failure; Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cushing Syndrome; Dementia, Vascular; Diabetes Mellitus, Type 2; Eisenmenger Complex; Essential Hypertension; Gastroparesis; Hypertension; Multiple Myeloma; Obesity; Priapism; Scleroderma, Systemic; Stroke; Glucose Intolerance; Heart Defects, Congenital; Insulin Resistance; Lung Diseases, Interstitial; Muscular Dystrophy, Duchenne; Raynaud Disease; Transposition of Great Vessels; Erectile Dysfunction; Hypertension, Pulmonary; Prostatic Hyperplasia; Pulmonary Arterial Hypertension

Phosphodiesterase 5A inhibitor

Small molecule

Approved

EMERGENCY MEDICINE; MUSCULOSKELETAL; NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER

ORAL

Essential Tremor; Marijuana Abuse; Tobacco Use Disorder; Carcinoma, Squamous Cell; Cough; Oropharyngeal Neoplasms; Pregnancy; Refractive Errors; Alcoholism; Complex Regional Pain Syndromes; Diabetes Mellitus; Dry Eye Syndromes; Irritable Bowel Syndrome; Nausea; Pancreatitis, Chronic; Pruritus; Urinary Bladder, Overactive; Anxiety; Anxiety Disorders; Breast Neoplasms; Chronic Pain; Dementia; Depressive Disorder; Diabetic Neuropathies; Epilepsies, Partial; Epilepsy, Complex Partial; Epilepsy, Tonic-Clonic; Fractures, Bone; Herpes Zoster; Intervertebral Disc Degeneration; Migraine Disorders; Mononeuropathies; Muscle Cramp; Neuralgia, Postherpetic; Neurotic Disorders; Opioid-Related Disorders; Osteoarthritis; Pain; Peripheral Nervous System Diseases; Prostatitis; Radiculopathy; Restless Legs Syndrome; Schizophrenia; Sleep Initiation and Maintenance Disorders; Epilepsy; Fibromyalgia; Neuralgia; Seizures; Spinal Cord Injuries

Voltage-gated calcium channel modulator


Small molecule Approved NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER ORAL Marijuana Abuse; Anxiety Disorders; Sleep Apnea, Obstructive; Sleep Initiation and Maintenance Disorders GABA-A receptor; anion channel positive allosteric modulator

Small molecule

Approved

NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER

ORAL

Marijuana Abuse; Burns; Migraine with Aura; Migraine without Aura; Pulmonary Disease, Chronic Obstructive; Severe Acute Respiratory Syndrome; Sleep Apnea, Obstructive; Sleep Wake Disorders; Substance-Related Disorders; Tobacco Use Disorder; Bipolar Disorder; Depressive Disorder; Sleep Initiation and Maintenance Disorders

Melatonin receptor agonist


Small molecule Approved NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER; PEDIATRICS ORAL Neuralgia; Epilepsy; Dementia; Depressive Disorder; Epilepsia Partialis Continua; Epilepsies, Myoclonic; Low Back Pain; Pain; Schizophrenia; Anxiety; Lennox Gastaut Syndrome; Seizures GABA-A receptor; anion channel positive allosteric modulator


Small molecule Approved NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER ORAL Obsessive-Compulsive Disorder; Anxiety; Autistic Disorder; Bipolar Disorder; Dementia; Depressive Disorder; Psychotic Disorders; Schizophrenia Dopamine D2 receptor antagonist


Small molecule Approved NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER TRANSDERMAL Alzheimer Disease; Fibromyalgia; Stroke; Parkinson Disease; Restless Legs Syndrome D2-like dopamine receptor agonist

Small molecule

Approved

NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER

ORAL

Carcinoma, Non-Small-Cell Lung; Head and Neck Neoplasms; Esophageal Neoplasms; Glioma; Multiple Sclerosis; Neoplasms; Schizophrenia; Sleep Initiation and Maintenance Disorders; Stroke; Brain Injuries; Depressive Disorder; Disorders of Excessive Somnolence; Fatigue; Obesity; Attention Deficit Disorder with Hyperactivity; Narcolepsy; Sleep Apnea, Obstructive; Sleep Wake Disorders

Dopamine transporter inhibitor


Small molecule Approved NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER; PEDIATRICS ORAL Pain; Epilepsy; Lennox Gastaut Syndrome; Seizures Sodium channel alpha subunit blocker

Small molecule

Approved

NEUROLOGY DRUGS & NERVOUS SYSTEM

TOPICAL

Amyotrophic Lateral Sclerosis; Brain Injuries; Cough; Migraine Disorders; Pruritus; Stroke; Facial Pain; HIV Infections; Hypertension, Pulmonary; Myofascial Pain Syndromes; Nausea; Neuralgia, Postherpetic; Neuroma; Tennis Elbow; Vomiting; Angina, Stable; Breast Neoplasms; Diabetic Neuropathies; Head and Neck Neoplasms; Herpes Zoster; Osteoarthritis, Knee; Peripheral Nervous System Diseases; Arthralgia; Arthritis; Back Pain; Bursitis; Contusions; Muscle Cramp; Myalgia; Neuralgia; Osteoarthritis; Pain; Sprains and Strains; Tendinopathy

Vanilloid receptor opener


Enzyme Approved NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER INTRAVENOUS Gaucher Disease Glucocerebroside hydrolytic enzyme