Trade Names: | |
Synonyms: | |
Status: | Approved (1982) |
Entry Type: | Small molecule |
Molecule Category: | Salt Prodrug |
UNII: | 927L42J563 |
Parent Compound: | ACYCLOVIR |
InChI Key | RMLUKZWYIKEASN-UHFFFAOYSA-M |
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Smile | |
InChI |
|
Property Name | Value |
---|---|
Molecular Formula | C8H10N5NaO3 |
Molecular Weight | 247.19 |
AlogP | -0.92 |
Hydrogen Bond Acceptor | 8.0 |
Hydrogen Bond Donor | 3.0 |
Number of Rotational Bond | 4.0 |
Polar Surface Area | 119.31 |
Molecular species | NEUTRAL |
Aromatic Rings | 2.0 |
Heavy Atoms | 16.0 |
Action | Mechanism of Action | Reference |
---|---|---|
INHIBITOR | Human herpesvirus 1 DNA polymerase inhibitor | FDA |
Mesh Heading | Maximum Phase | Mesh ID | Reference |
---|---|---|---|
Herpes Labialis | 3 | D006560 | ClinicalTrials |
Cytomegalovirus Infections | 3 | D003586 | ClinicalTrials |
Infections | 3 | D007239 | ClinicalTrials |
Multiple Sclerosis | 3 | D009103 | ClinicalTrials |
Neoplasms | 3 | D009369 | ClinicalTrials |
Keratitis, Herpetic | 3 | D016849 | ClinicalTrials |
Herpes Simplex | 3 | D006561 | ClinicalTrials |
HIV Infections | 2 | D015658 | ClinicalTrials |
Carcinoma, Non-Small-Cell Lung | 2 | D002289 | ClinicalTrials |
Prostatic Neoplasms, Castration-Resistant | 2 | D064129 | ClinicalTrials |
Meniere Disease | 2 | D008575 | ClinicalTrials |
Kidney Diseases | 1 | D007674 | ClinicalTrials |
Leukemia, Biphenotypic, Acute | 1 | D015456 | ClinicalTrials |
Lymphoma, Large B-Cell, Diffuse | 1 | D016403 | ClinicalTrials |
Resources | Reference |
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ChEMBL | CHEMBL1200380 |
FDA SRS | 927L42J563 |
PubChem | 23665721 |
SureChEMBL | SCHEMBL40722 |