Trade Names:
Synonyms:
Status: Approved (1998)
Entry Type: Antibody
Molecule Category: UNKNOWN
ATC: L04AC02
UNII: 9927MT646M

Pharmacology

Action Mechanism of Action Reference
INHIBITOR Interleukin-2 receptor inhibitor DailyMed

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Graft vs Host Disease 3 D006086 ClinicalTrials
Reperfusion Injury 3 D015427 ClinicalTrials
Emphysema 3 D004646 ClinicalTrials
Infections 3 D007239 ClinicalTrials
Diabetes Mellitus, Type 1 3 D003922 ClinicalTrials
Glioblastoma 2 D005909 ClinicalTrials
Granuloma, Lethal Midline 2 D006103 ClinicalTrials
Colitis, Ulcerative 2 D003093 ClinicalTrials
Renal Insufficiency, Chronic 2 D051436 ClinicalTrials
Uveitis 2 D014605 ClinicalTrials
Hodgkin Disease 2 D006689 ClinicalTrials
Amyotrophic Lateral Sclerosis 2 D000690 ClinicalTrials
Glomerulosclerosis, Focal Segmental 2 D005923 ClinicalTrials
Kidney Diseases 2 D007674 ClinicalTrials
Kidney Tubular Necrosis, Acute 1 D007683 ClinicalTrials
DiGeorge Syndrome 1 D004062 ClinicalTrials
Leukemia, Myeloid, Acute 1 D015470 ClinicalTrials
Neoplasms 1 D009369 ClinicalTrials
Multiple Myeloma 1 D009101 ClinicalTrials
Uremia 1 D014511 ClinicalTrials

Adverse Reactions

System Organ Classification (SOC)
Relative Frequency (%)
Investigations
26.23
Injury, poisoning and procedural complications
9.29
Infections and infestations
8.68
Renal and urinary disorders
8.51
General disorders and administration site conditions
6.52
Gastrointestinal disorders
5.48
Respiratory, thoracic and mediastinal disorders
4.55
Blood and lymphatic system disorders
4.08
Immune system disorders
3.9
Vascular disorders
3.78
Nervous system disorders
3.55
Metabolism and nutrition disorders
3.51
Cardiac disorders
2.75

Cross References

Resources Reference
CAS NUMBER 179045-86-4
ChEMBL CHEMBL1201439
FDA SRS 9927MT646M
Guide to Pharmacology 6879