Trade Names: | |
Synonyms: | |
Status: | Approved (2008) |
Entry Type: | Small molecule |
Molecule Category: | Salt |
UNII: | 981Y8SX18M |
Parent Compound: | BENDAMUSTINE |
InChI Key | ZHSKUOZOLHMKEA-UHFFFAOYSA-N |
---|---|
Smile | |
InChI |
|
Property Name | Value |
---|---|
Molecular Formula | C16H22Cl3N3O2 |
Molecular Weight | 394.73 |
AlogP | 3.26 |
Hydrogen Bond Acceptor | 4.0 |
Hydrogen Bond Donor | 1.0 |
Number of Rotational Bond | 9.0 |
Polar Surface Area | 58.36 |
Molecular species | ACID |
Aromatic Rings | 2.0 |
Heavy Atoms | 23.0 |
Action | Mechanism of Action | Reference |
---|---|---|
INHIBITOR | DNA inhibitor | FDA |
Mesh Heading | Maximum Phase | Mesh ID | Reference |
---|---|---|---|
Lymphoma, Non-Hodgkin | 4 | D008228 | ClinicalTrials |
Leukemia | 2 | D007938 | ClinicalTrials |
Lymphoma | 2 | D008223 | ClinicalTrials |
Multiple Myeloma | 2 | D009101 | ClinicalTrials |
Astrocytoma | 2 | D001254 | ClinicalTrials |
Oligodendroglioma | 2 | D009837 | ClinicalTrials |
Gliosarcoma | 2 | D018316 | ClinicalTrials |
Lymphoma, Mantle-Cell | 2 | D020522 | ClinicalTrials |
Lung Neoplasms | 2 | D008175 | ClinicalTrials |
Lymphoma, Follicular | 2 | D008224 | ClinicalTrials |
Hodgkin Disease | 2 | D006689 | ClinicalTrials |
Neoplasms | 2 | D009369 | ClinicalTrials |
Amyloidosis, Familial | 2 | D028226 | ClinicalTrials |
Hodgkin Disease | 2 | D006689 | ClinicalTrials |
Lymphoma, Large B-Cell, Diffuse | 2 | D016403 | ClinicalTrials |
Hematologic Neoplasms | 1 | D019337 | ClinicalTrials |
Resources | Reference |
---|---|
ChEMBL | CHEMBL1201734 |
EPA CompTox | DTXSID40188912 |
FDA SRS | 981Y8SX18M |
PubChem | 77082 |
SureChEMBL | SCHEMBL18843 |