BETAXOLOL HYDROCHLORIDE

Search structure
Trade Names:
Synonyms:
Status: Approved (1985)
Entry Type: Small molecule
Molecule Category: Salt
UNII: 6X97D2XT0O
Parent Compound: BETAXOLOL

Structure
InChI Key CHDPSNLJFOQTRK-UHFFFAOYSA-N
Smile CC(C)NCC(O)COc1ccc(CCOCC2CC2)cc1.Cl
InChI
InChI=1S/C18H29NO3.ClH/c1-14(2)19-11-17(20)13-22-18-7-5-15(6-8-18)9-10-21-12-16-3-4-16;/h5-8,14,16-17,19-20H,3-4,9-13H2,1-2H3;1H

Physicochemical Descriptors

Property Name Value
Molecular Formula C18H30ClNO3
Molecular Weight 343.9
AlogP 2.39
Hydrogen Bond Acceptor 4.0
Hydrogen Bond Donor 2.0
Number of Rotational Bond 11.0
Polar Surface Area 50.72
Molecular species BASE
Aromatic Rings 1.0
Heavy Atoms 22.0

Pharmacology

Action Mechanism of Action Reference
ANTAGONIST Beta-1 adrenergic receptor antagonist DailyMed
Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) Monoamine receptor Adrenergic receptor
- - 3-3 - -

Indications

Mesh Heading Maximum Phase Mesh ID Reference

Related Entries

Parent
Mixture
Mixture

Adverse Reactions

SOC By Demographic Distribution
System Organ Classification (SOC)
Relative Frequency (%)
Eye disorders
18.49
Nervous system disorders
15.41
Respiratory, thoracic and mediastinal disorders
10.92
General disorders and administration site conditions
9.52
Cardiac disorders
8.12
Product issues
6.16
Injury, poisoning and procedural complications
5.6
Psychiatric disorders
4.48
Immune system disorders
3.64
Investigations
2.8
Vascular disorders
2.8
Ear and labyrinth disorders
2.52
Gastrointestinal disorders
2.52

Cross References

Resources Reference
ChEBI 643228
ChEMBL CHEMBL1691
FDA SRS 6X97D2XT0O
PubChem 107952
SureChEMBL SCHEMBL22721924
ZINC ZINC01530568
CONTENTS