Trade Names:
Synonyms:
Status: Approved (2017)
Entry Type: Antibody
Molecule Category: UNKNOWN
ATC: L04AC12
UNII: 6ZA31Y954Z

Pharmacology

Action Mechanism of Action Reference
ANTAGONIST Interleukin-17 receptor A antagonist PubMed
Primary Target
Interleukin 17 receptor A

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Psoriasis 4 D011565 FDA
Psoriasis 4 D011565 ClinicalTrials
Psoriasis 4 D011565 ClinicalTrials
Arthritis, Psoriatic 3 D015535 ClinicalTrials
Spondylitis, Ankylosing 3 D013167 ClinicalTrials
Asthma 2 D001249 ClinicalTrials
Arthritis, Rheumatoid 2 D001172 ClinicalTrials
Hidradenitis Suppurativa 2 D017497 ClinicalTrials
Crohn Disease 2 D003424 ClinicalTrials
Scleroderma, Systemic 1 D012595 ClinicalTrials

Adverse Reactions

System Organ Classification (SOC)
Relative Frequency (%)
Skin and subcutaneous tissue disorders
13.19
Infections and infestations
12.37
General disorders and administration site conditions
9.02
Immune system disorders
8.07
Musculoskeletal and connective tissue disorders
8.0
Gastrointestinal disorders
7.31
Nervous system disorders
7.01
Respiratory, thoracic and mediastinal disorders
6.19
Psychiatric disorders
5.33
Injury, poisoning and procedural complications
5.06
Vascular disorders
3.21
Cardiac disorders
2.22
Renal and urinary disorders
2.12

Cross References

Resources Reference
CAS NUMBER 1174395-19-7
ChEMBL CHEMBL1742996
FDA SRS 6ZA31Y954Z
Guide to Pharmacology 7540