Trade Names: | |
Synonyms: | |
Status: | Approved (1957) |
Entry Type: | Small molecule |
Molecule Category: | Parent |
UNII: | IXA7C9ZN03 |
InChI Key | SRGKFVAASLQVBO-BTJKTKAUSA-N |
---|---|
Smile | |
InChI |
|
Property Name | Value |
---|---|
Molecular Formula | C20H23BrN2O4 |
Molecular Weight | 435.32 |
AlogP | 3.93 |
Hydrogen Bond Acceptor | 2.0 |
Hydrogen Bond Donor | 0.0 |
Number of Rotational Bond | 5.0 |
Polar Surface Area | 16.13 |
Molecular species | BASE |
Aromatic Rings | 2.0 |
Heavy Atoms | 19.0 |
Action | Mechanism of Action | Reference |
---|---|---|
ANTAGONIST | Histamine H1 receptor antagonist | PubMed |
Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
---|---|---|---|---|---|---|
Transporter
Electrochemical transporter
SLC superfamily of solute carriers
SLC21/SLCO family of organic anion transporting polypeptides
|
- | - | - | - | 89 |
Mesh Heading | Maximum Phase | Mesh ID | Reference |
---|---|---|---|
Hypersensitivity | 4 | D006967 | ClinicalTrials |
Resources | Reference |
---|---|
ChEBI | 3184 |
ChEMBL | CHEMBL1200961 |
EPA CompTox | DTXSID2052657 |
FDA SRS | IXA7C9ZN03 |
PubChem | 5281067 |
SureChEMBL | SCHEMBL41913 |