CARISOPRODOL

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Trade Names:
Synonyms:
Status: Approved (1959) Withdrawn (2007)
Entry Type: Small molecule
Molecule Category: Parent
ATC: M03BA02
UNII: 21925K482H

Structure
InChI Key OFZCIYFFPZCNJE-UHFFFAOYSA-N
Smile CCCC(C)(COC(N)=O)COC(=O)NC(C)C
InChI
InChI=1S/C12H24N2O4/c1-5-6-12(4,7-17-10(13)15)8-18-11(16)14-9(2)3/h9H,5-8H2,1-4H3,(H2,13,15)(H,14,16)

Physicochemical Descriptors

Property Name Value
Molecular Formula C12H24N2O4
Molecular Weight 260.33
AlogP 2.02
Hydrogen Bond Acceptor 4.0
Hydrogen Bond Donor 2.0
Number of Rotational Bond 7.0
Polar Surface Area 90.65
Molecular species NEUTRAL
Aromatic Rings 0.0
Heavy Atoms 18.0

Pharmacology

Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Enzyme Hydrolase
- - - - 15
Transporter Electrochemical transporter SLC superfamily of solute carriers SLC21/SLCO family of organic anion transporting polypeptides
- - - - 104
Transporter Electrochemical transporter SLC superfamily of solute carriers SLC22 family of organic cation and anion transporters
- - - - 20

Metabolites

visNetwork

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Low Back Pain 3 D017116 ClinicalTrials

Related Entries

MCS

Mixture
Mixture

Side Effects from Label

Adverse Reactions

SOC By Demographic Distribution
System Organ Classification (SOC)
Relative Frequency (%)
Psychiatric disorders
19.11
General disorders and administration site conditions
17.34
Injury, poisoning and procedural complications
11.66
Nervous system disorders
11.3
Respiratory, thoracic and mediastinal disorders
8.41
Cardiac disorders
7.86
Gastrointestinal disorders
4.25
Musculoskeletal and connective tissue disorders
3.51
Vascular disorders
2.99
Immune system disorders
2.8
Investigations
2.3

Cross References

Resources Reference
CAS NUMBER 78-44-4
ChEBI 3419
ChEMBL CHEMBL1233
DrugBank DB00395
DrugCentral 509
EPA CompTox DTXSID8024733
FDA SRS 21925K482H
Human Metabolome Database HMDB0014539
Guide to Pharmacology 7610
KEGG C07927
PharmGKB PA448809
PubChem 2576
SureChEMBL SCHEMBL33286
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