Pharmacology

Action Mechanism of Action Reference
INHIBITOR TNF-alpha inhibitor DailyMed

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Spondylitis, Ankylosing 4 D013167 ClinicalTrials
Crohn Disease 4 D003424 ClinicalTrials
Psoriasis 3 D011565 ClinicalTrials
Cystitis, Interstitial 3 D018856 ClinicalTrials
Arthritis, Juvenile 3 D001171 ClinicalTrials
Colitis, Ulcerative 2 D003093 ClinicalTrials

Adverse Reactions

System Organ Classification (SOC)
Relative Frequency (%)
Infections and infestations
15.68
General disorders and administration site conditions
10.73
Respiratory, thoracic and mediastinal disorders
10.65
Skin and subcutaneous tissue disorders
7.7
Injury, poisoning and procedural complications
7.47
Gastrointestinal disorders
7.41
Musculoskeletal and connective tissue disorders
6.86
Immune system disorders
4.63
Nervous system disorders
4.61
Vascular disorders
3.34
Renal and urinary disorders
2.46
Cardiac disorders
2.34
Pregnancy, puerperium and perinatal conditions
2.18
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
2.15

Cross References

Resources Reference
CAS NUMBER 428863-50-7
ChEMBL CHEMBL1201831
FDA SRS UMD07X179E
Guide to Pharmacology 6774