Structure

InChI Key WIIZWVCIJKGZOK-RKDXNWHRSA-N
Smile O=C(N[C@H](CO)[C@H](O)c1ccc([N+](=O)[O-])cc1)C(Cl)Cl
InChI
InChI=1S/C11H12Cl2N2O5/c12-10(13)11(18)14-8(5-16)9(17)6-1-3-7(4-2-6)15(19)20/h1-4,8-10,16-17H,5H2,(H,14,18)/t8-,9-/m1/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C11H12Cl2N2O5
Molecular Weight 323.13
AlogP 0.91
Hydrogen Bond Acceptor 5.0
Hydrogen Bond Donor 3.0
Number of Rotational Bond 6.0
Polar Surface Area 112.7
Molecular species NEUTRAL
Aromatic Rings 1.0
Heavy Atoms 20.0

Pharmacology

Action Mechanism of Action Reference
INHIBITOR Bacterial 70S ribosome inhibitor PubMed PubMed Wikipedia

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Osteomyelitis 0 D010019 ClinicalTrials

Related Entries

MCS

Salt
Mixture
Mixture
Mixture
Mixture
Mixture

Adverse Reactions

System Organ Classification (SOC)
Relative Frequency (%)
Blood and lymphatic system disorders
18.47
Nervous system disorders
13.25
General disorders and administration site conditions
8.43
Eye disorders
8.03
Gastrointestinal disorders
7.23
Skin and subcutaneous tissue disorders
6.83
Immune system disorders
6.02
Injury, poisoning and procedural complications
6.02
Infections and infestations
4.82
Psychiatric disorders
4.82
Vascular disorders
4.82
Cardiac disorders
3.21
Investigations
2.01
Respiratory, thoracic and mediastinal disorders
2.01

Cross References

Resources Reference
CAS NUMBER 56-75-7
ChEBI 17698
ChEMBL CHEMBL130
DrugBank DB00446
DrugCentral 589
EPA CompTox DTXSID7020265
FDA SRS 66974FR9Q1
Human Metabolome Database HMDB0014589
Guide to Pharmacology 10901
KEGG C00918
PDB CLM
PubChem 5959
SureChEMBL SCHEMBL16111
ZINC ZINC000000113382