CIMETIDINE HYDROCHLORIDE

Search structure
Trade Names:
Synonyms:
Status: Approved (1977)
Entry Type: Small molecule
Molecule Category: Salt
UNII: WF10491673
Parent Compound: CIMETIDINE

Structure
InChI Key QJHCNBWLPSXHBL-UHFFFAOYSA-N
Smile CN/C(=N\CCSCc1nc[nH]c1C)NC#N.Cl
InChI
InChI=1S/C10H16N6S.ClH/c1-8-9(16-7-15-8)5-17-4-3-13-10(12-2)14-6-11;/h7H,3-5H2,1-2H3,(H,15,16)(H2,12,13,14);1H

Physicochemical Descriptors

Property Name Value
Molecular Formula C10H17ClN6S
Molecular Weight 288.81
AlogP 0.6
Hydrogen Bond Acceptor 4.0
Hydrogen Bond Donor 3.0
Number of Rotational Bond 5.0
Polar Surface Area 88.89
Molecular species NEUTRAL
Aromatic Rings 1.0
Heavy Atoms 17.0

Pharmacology

Action Mechanism of Action Reference
ANTAGONIST Histamine H2 receptor antagonist ISBN

Metabolites

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Related Entries

Parent

Adverse Reactions

SOC By Demographic Distribution
System Organ Classification (SOC)
Relative Frequency (%)
General disorders and administration site conditions
37.5
Cardiac disorders
12.5
Skin and subcutaneous tissue disorders
12.5
Blood and lymphatic system disorders
6.25
Infections and infestations
6.25
Injury, poisoning and procedural complications
6.25
Investigations
6.25
Psychiatric disorders
6.25
Vascular disorders
6.25

Cross References

Resources Reference
ChEBI 50362
ChEMBL CHEMBL1201051
FDA SRS WF10491673
PubChem 50963
SureChEMBL SCHEMBL42142
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