Trade Names: | |
Synonyms: | |
Status: | Approved (1997) |
Entry Type: | Small molecule |
Molecule Category: | Salt Prodrug |
UNII: | 08I79HTP27 |
Parent Compound: | CLOPIDOGREL |
InChI Key | FDEODCTUSIWGLK-RSAXXLAASA-N |
---|---|
Smile | |
InChI |
|
Property Name | Value |
---|---|
Molecular Formula | C16H18ClNO6S2 |
Molecular Weight | 419.91 |
AlogP | 3.67 |
Hydrogen Bond Acceptor | 4.0 |
Hydrogen Bond Donor | 0.0 |
Number of Rotational Bond | 3.0 |
Polar Surface Area | 29.54 |
Molecular species | NEUTRAL |
Aromatic Rings | 2.0 |
Heavy Atoms | 21.0 |
Action | Mechanism of Action | Reference |
---|---|---|
ANTAGONIST | Purinergic receptor P2Y12 antagonist | DailyMed |
Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
---|---|---|---|---|---|---|
Transporter
Electrochemical transporter
SLC superfamily of solute carriers
SLC21/SLCO family of organic anion transporting polypeptides
|
- | - | - | - | 145 | |
Transporter
Primary active transporter
ATP-binding cassette
ABCB subfamily
|
- | 72000 | - | - | - |
Mesh Heading | Maximum Phase | Mesh ID | Reference |
---|---|---|---|
Gastrointestinal Hemorrhage | 3 | D006471 | ClinicalTrials |
Breast Neoplasms | 2 | D001943 | ClinicalTrials |
Coronary Disease | 1 | D003327 | ClinicalTrials |
Resources | Reference |
---|---|
ChEBI | 3759 |
ChEMBL | CHEMBL1083385 |
EPA CompTox | DTXSID4046024 |
FDA SRS | 08I79HTP27 |
PubChem | 115366 |
SureChEMBL | SCHEMBL33556 |