Trade Names: | |
Synonyms: | |
Status: | Approved (2016) |
Entry Type: | Small molecule |
Molecule Category: | UNKNOWN |
ATC: | D11AH06 |
UNII: | Q2R47HGR7P |
InChI Key | USZAGAREISWJDP-UHFFFAOYSA-N |
---|---|
Smile | |
InChI |
|
Property Name | Value |
---|---|
Molecular Formula | C14H10BNO3 |
Molecular Weight | 251.05 |
AlogP | None |
Hydrogen Bond Acceptor | None |
Hydrogen Bond Donor | None |
Number of Rotational Bond | None |
Polar Surface Area | None |
Molecular species | None |
Aromatic Rings | None |
Heavy Atoms | None |
Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
---|---|---|---|---|---|---|
Enzyme
Phosphodiesterase
Phosphodiesterase 1
Phosphodiesterase 1A
|
- | 6100 | - | - | - | |
Enzyme
Phosphodiesterase
Phosphodiesterase 3
Phosphodiesterase 3A
|
- | 6400 | - | - | - | |
Enzyme
Phosphodiesterase
Phosphodiesterase 3
Phosphodiesterase 3B
|
- | 6400 | - | - | - | |
Enzyme
Phosphodiesterase
Phosphodiesterase 4
Phosphodiesterase 4A
|
- | 110-490 | - | - | - | |
Enzyme
Phosphodiesterase
Phosphodiesterase 4
Phosphodiesterase 4B
|
- | 110-490 | - | - | - | |
Enzyme
Phosphodiesterase
Phosphodiesterase 4
Phosphodiesterase 4C
|
- | 110-490 | - | - | - | |
Enzyme
Phosphodiesterase
Phosphodiesterase 4
Phosphodiesterase 4D
|
- | 110-490 | - | - | - | |
Enzyme
Phosphodiesterase
Phosphodiesterase 7
Phosphodiesterase 7A
|
- | 730 | - | - | - |
Mesh Heading | Maximum Phase | Mesh ID | Reference |
---|---|---|---|
Dermatitis, Atopic | 4 | D003876 | ClinicalTrials |
Psoriasis | 2 | D011565 | ClinicalTrials |
Scleroderma, Localized | 2 | D012594 | ClinicalTrials |
Alopecia Areata | 2 | D000506 | ClinicalTrials |
Dermatitis | 2 | D003872 | ClinicalTrials |
Resources | Reference |
---|---|
CAS NUMBER | 906673-24-3 |
ChEBI | 134677 |
ChEMBL | CHEMBL484785 |
DrugBank | DB05219 |
DrugCentral | 5201 |
EPA CompTox | DTXSID10238231 |
FDA SRS | Q2R47HGR7P |
Guide to Pharmacology | 9151 |
PubChem | 44591583 |
SureChEMBL | SCHEMBL595261 |
ZINC | ZINC000169748244 |