Structure

InChI Key UHDGCWIWMRVCDJ-CCXZUQQUSA-N
Smile Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@@H]2O)c(=O)n1
InChI
InChI=1S/C9H13N3O5/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16)/t4-,6-,7+,8-/m1/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C9H13N3O5
Molecular Weight 243.22
AlogP -2.56
Hydrogen Bond Acceptor 8.0
Hydrogen Bond Donor 4.0
Number of Rotational Bond 2.0
Polar Surface Area 130.83
Molecular species NEUTRAL
Aromatic Rings 1.0
Heavy Atoms 17.0

Experimental and Estimated Properties

Property Name Value Unit Method
log P (octanol-water) -2.460 - EST
Atmospheric OH Rate Constant 1.23E-10 cm3/molecule-sec EST
Melting Point 212.5 deg C EXP

Pharmacology

Action Mechanism of Action Reference
INHIBITOR DNA inhibitor DailyMed

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Precursor Cell Lymphoblastic Leukemia-Lymphoma 4 D054198 ClinicalTrials
Leukemia, Myeloid, Acute 4 D015470 ClinicalTrials
Leukemia, Myeloid, Acute 4 D015470 ClinicalTrials
Precursor Cell Lymphoblastic Leukemia-Lymphoma 4 D054198 ClinicalTrials
Leukemia, Myeloid, Acute 4 D015470 ClinicalTrials
Neoplasms 4 D009369 ClinicalTrials
Leukemia, Monocytic, Acute 3 D007948 ClinicalTrials
Leukemia, Myelomonocytic, Acute 3 D015479 ClinicalTrials
Leukemia, Myelogenous, Chronic, BCR-ABL Positive 3 D015464 ClinicalTrials
Lymphoma, Large B-Cell, Diffuse 3 D016403 ClinicalTrials
Melanoma 3 D008545 ClinicalTrials
Malaria 3 D008288 ClinicalTrials
Multiple Myeloma 3 D009101 ClinicalTrials
Leukemia, Megakaryoblastic, Acute 3 D007947 ClinicalTrials
Leukemia, Basophilic, Acute 3 D015471 ClinicalTrials
Graft vs Host Disease 3 D006086 ClinicalTrials
Lymphoma 3 D008223 ClinicalTrials
Leukemia 3 D007938 ClinicalTrials
Leukemia, Promyelocytic, Acute 3 D015473 ClinicalTrials
Lymphoma, Mantle-Cell 3 D020522 ClinicalTrials
Leukemia, Biphenotypic, Acute 3 D015456 ClinicalTrials
Lymphoma, Follicular 3 D008224 ClinicalTrials
Hodgkin Disease 3 D006689 ClinicalTrials
Myelodysplastic Syndromes 3 D009190 ClinicalTrials
Leukemia, Biphenotypic, Acute 3 D015456 ClinicalTrials
Anemia, Refractory 3 D000753 ClinicalTrials
Myeloproliferative Disorders 3 D009196 ClinicalTrials
Lymphoma, Non-Hodgkin 3 D008228 ClinicalTrials
Sarcoma, Myeloid 3 D023981 ClinicalTrials
Histiocytosis, Langerhans-Cell 3 D006646 ClinicalTrials
Sarcoma, Myeloid 3 D023981 ClinicalTrials
Leukemia, Erythroblastic, Acute 3 D004915 ClinicalTrials
Renal Insufficiency, Chronic 3 D051436 ClinicalTrials
Leukemia, Myelomonocytic, Chronic 3 D015477 ClinicalTrials
Leukemia, Erythroblastic, Acute 3 D004915 ClinicalTrials
Myeloproliferative Disorders 3 D009196 ClinicalTrials
Anemia, Refractory, with Excess of Blasts 3 D000754 ClinicalTrials
Breast Neoplasms 3 D001943 ClinicalTrials
Hodgkin Disease 3 D006689 ClinicalTrials
Lymphoma, Follicular 3 D008224 ClinicalTrials
Leukemia, Biphenotypic, Acute 3 D015456 ClinicalTrials
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 3 D054218 ClinicalTrials
Sarcoma 2 D012509 ClinicalTrials
Neutropenia 2 D009503 ClinicalTrials
Leukemia, Myelomonocytic, Juvenile 2 D054429 ClinicalTrials
Urinary Bladder, Overactive 2 D053201 ClinicalTrials
Ovarian Neoplasms 2 D010051 ClinicalTrials
Prostatic Neoplasms, Castration-Resistant 2 D064129 ClinicalTrials
Lymphoma, AIDS-Related 2 D016483 ClinicalTrials
Stiff-Person Syndrome 2 D016750 ClinicalTrials
Leukemia, Lymphocytic, Chronic, B-Cell 2 D015451 ClinicalTrials
Leukemia-Lymphoma, Adult T-Cell 2 D015459 ClinicalTrials
Lupus Erythematosus, Systemic 2 D008180 ClinicalTrials
Hematologic Neoplasms 2 D019337 ClinicalTrials
Neuromyelitis Optica 2 D009471 ClinicalTrials
Myasthenia Gravis 2 D009157 ClinicalTrials
Polyradiculoneuropathy, Chronic Inflammatory Demyelinating 2 D020277 ClinicalTrials
Blast Crisis 2 D001752 ClinicalTrials
Central Nervous System Neoplasms 2 D016543 ClinicalTrials
Meningitis, Aseptic 2 D008582 ClinicalTrials
Lymphoma, Large-Cell, Anaplastic 2 D017728 ClinicalTrials
Opsoclonus-Myoclonus Syndrome 2 D053578 ClinicalTrials
Multiple Sclerosis, Relapsing-Remitting 2 D020529 ClinicalTrials
Burkitt Lymphoma 2 D002051 ClinicalTrials
Medulloblastoma 2 D008527 ClinicalTrials
Lymphoma, T-Cell, Peripheral 2 D016411 ClinicalTrials
Brain Neoplasms 1 D001932 ClinicalTrials
Glioblastoma 1 D005909 ClinicalTrials
Thrombocythemia, Essential 1 D013920 ClinicalTrials
Alopecia 1 D000505 ClinicalTrials
Polycythemia Vera 1 D011087 ClinicalTrials
Leukemia, Plasma Cell 1 D007952 ClinicalTrials
Primary Myelofibrosis 1 D055728 ClinicalTrials

Related Entries

MCS

Scaffolds

Salt
Mixture

Side Effects from Label

Side effects Relative Frequency (%) Labels
Eye disorders Conjunctivitis 80.0
Nervous system disorders Headache 56.4
Nervous system disorders Headache 56.0
General disorders and administration site conditions Asthenia 53.6
Gastrointestinal disorders Nausea 53.6
Nervous system disorders Headache 51.5
General disorders and administration site conditions Asthenia 46.4
General disorders and administration site conditions Fatigue 46.4
Investigations Body temperature increased 45.5
Gastrointestinal disorders Nausea 45.5
Gastrointestinal disorders Vomiting 43.6
Investigations Body temperature increased 42.9
Injury, poisoning and procedural complications Arachnoiditis 42.4
Nervous system disorders Headache 42.3
Injury, poisoning and procedural complications Arachnoiditis 42.0
General disorders and administration site conditions Asthenia 40.1
General disorders and administration site conditions Asthenia 39.4
Nervous system disorders Confusional state 36.4
General disorders and administration site conditions Feeling abnormal 36.4
Blood and lymphatic system disorders Neutropenia 36.4
Injury, poisoning and procedural complications Arachnoiditis 36.0
Nervous system disorders Confusional state 36.0
General disorders and administration site conditions Feeling abnormal 36.0
Injury, poisoning and procedural complications Arachnoiditis 35.7
Nervous system disorders Confusional state 33.5
General disorders and administration site conditions Feeling abnormal 33.5
Gastrointestinal disorders Nausea 33.3
Gastrointestinal disorders Vomiting 33.3
General disorders and administration site conditions Asthenia 33.0
Nervous system disorders Confusional state 33.0
General disorders and administration site conditions Feeling abnormal 33.0
Gastrointestinal disorders Diarrhoea 32.1
Nervous system disorders Headache 32.1
Blood and lymphatic system disorders Thrombocytopenia 32.1
Gastrointestinal disorders Vomiting 32.1
Investigations Body temperature increased 32.0
Investigations Body temperature increased 31.5
Gastrointestinal disorders Nausea 30.8
General disorders and administration site conditions Gait disturbance 29.0
General disorders and administration site conditions Gait disturbance 28.6
Musculoskeletal and connective tissue disorders Pain in extremity 28.6
Gastrointestinal disorders Vomiting 28.2
Nervous system disorders Headache 28.0
General disorders and administration site conditions Asthenia 27.3
Gastrointestinal disorders Diarrhoea 27.3
General disorders and administration site conditions Fatigue 27.3
Gastrointestinal disorders Constipation 25.0
Nervous system disorders Insomnia 25.0
Blood and lymphatic system disorders Neutropenia 25.0
Cardiac disorders Oedema peripheral 25.0
General disorders and administration site conditions Asthenia 24.9
Gastrointestinal disorders Constipation 24.9
General disorders and administration site conditions Fatigue 24.9
Gastrointestinal disorders Constipation 24.2
Blood and lymphatic system disorders Thrombocytopenia 24.2
Investigations Body temperature increased 24.0
Nervous system disorders Headache 24.0
Musculoskeletal and connective tissue disorders Back pain 23.7
General disorders and administration site conditions Gait disturbance 23.3
General disorders and administration site conditions Gait disturbance 23.0
Nervous system disorders Headache 23.0
Convulsion 22.0
Convulsion 21.8
Respiratory, thoracic and mediastinal disorders Cough 21.4
Cardiac disorders Dizziness 21.4
Cardiac disorders Dyspnoea 21.4
General disorders and administration site conditions Oedema 21.4
Musculoskeletal and connective tissue disorders Back pain 21.2
Convulsion 21.2
Cardiac disorders Dizziness 21.2
General disorders and administration site conditions Gait disturbance 21.2
Convulsion 21.0
Cardiac disorders Dizziness 21.0
General disorders and administration site conditions Gait disturbance 21.0
Convulsion 20.2
Convulsion 20.0
General disorders and administration site conditions Pain 20.0
Injury, poisoning and procedural complications Arachnoiditis 19.2
Musculoskeletal and connective tissue disorders Back pain 19.2
Investigations Body temperature increased 19.2
Injury, poisoning and procedural complications Arachnoiditis 19.0
General disorders and administration site conditions Asthenia 19.0
Cardiac disorders Dizziness 18.3
Blood and lymphatic system disorders Anaemia 18.2
Ear and labyrinth disorders Deafness 18.2
Metabolism and nutrition disorders Dehydration 18.2
Psychiatric disorders Depression 18.2
Hearing impaired 18.2
Vascular disorders Hypotension 18.2
Nervous system disorders Insomnia 18.2
Cardiac disorders Oedema peripheral 18.2
Infections and infestations Urinary tract infection 18.2
Cardiac disorders Dizziness 18.0
Gastrointestinal disorders Nausea 18.0
Nervous system disorders Tremor 18.0
Gastrointestinal disorders Vomiting 18.0
Blood and lymphatic system disorders Anaemia 17.9
Musculoskeletal and connective tissue disorders Back pain 17.9
General disorders and administration site conditions Decreased appetite 17.9
Gastrointestinal disorders Incontinence 17.9
General disorders and administration site conditions Pain 17.9
Cardiac disorders Tachycardia 17.9
Nervous system disorders Tremor 17.9
Infections and infestations Urinary tract infection 17.9
Gastrointestinal disorders Vomiting 17.0
Injury, poisoning and procedural complications Arachnoiditis 16.0
General disorders and administration site conditions Lethargy 16.0
Gastrointestinal disorders Nausea 16.0
Blood and lymphatic system disorders Thrombocytopenia 16.0
Gastrointestinal disorders Abdominal pain 15.2
Nervous system disorders Agitation 15.2
Gastrointestinal disorders Gastrointestinal pain 15.2
Vascular disorders Hypertension 15.2
Metabolism and nutrition disorders Hypokalaemia 15.2
Nervous system disorders Muscular weakness 15.2
Musculoskeletal and connective tissue disorders Neck pain 15.2
Musculoskeletal and connective tissue disorders Pain in extremity 15.2
Nervous system disorders Tremor 15.2
Nervous system disorders Tremor 15.0
Gastrointestinal disorders Abdominal pain 14.3
Musculoskeletal and connective tissue disorders Arthralgia 14.3
Psychiatric disorders Depression 14.3
Gastrointestinal disorders Gastrointestinal pain 14.3
General disorders and administration site conditions Lethargy 14.3
Musculoskeletal and connective tissue disorders Musculoskeletal discomfort 14.3
Musculoskeletal and connective tissue disorders Musculoskeletal stiffness 14.3
Musculoskeletal and connective tissue disorders Nuchal rigidity 14.3
Skin and subcutaneous tissue disorders Pruritus 14.3
Eye disorders Vision blurred 14.3
Convulsion 14.1
Investigations Body temperature increased 14.0
Nervous system disorders Confusional state 14.0
Convulsion 14.0
General disorders and administration site conditions Feeling abnormal 14.0
Nervous system disorders Memory impairment 14.0
Musculoskeletal and connective tissue disorders Neck pain 14.0
Nervous system disorders Insomnia 13.6
General disorders and administration site conditions Pain 13.6
Infections and infestations Urinary tract infection 13.6
Blood and lymphatic system disorders Anaemia 13.0
General disorders and administration site conditions Asthenia 13.0
Gastrointestinal disorders Nausea 13.0
Metabolism and nutrition disorders Dehydration 12.8
Blood and lymphatic system disorders Anaemia 12.1
General disorders and administration site conditions Decreased appetite 12.1
Gastrointestinal disorders Diarrhoea 12.1
Cardiac disorders Dyspnoea 12.1
Endocrine disorders Hyperglycaemia 12.1
Nervous system disorders Hypoaesthesia 12.1
Metabolism and nutrition disorders Hyponatraemia 12.1
General disorders and administration site conditions Lethargy 12.1
Nervous system disorders Memory impairment 12.1
General disorders and administration site conditions Mucosal inflammation 12.1
Nervous system disorders Neuropathy peripheral 12.1
Musculoskeletal and connective tissue disorders Pain in extremity 12.1
Eye disorders Vision blurred 12.1
Investigations Body temperature increased 12.0
Nervous system disorders Hypoaesthesia 12.0
Nervous system disorders Memory impairment 12.0
Nervous system disorders Neuropathy peripheral 12.0
Nervous system disorders Somnolence 12.0
Gastrointestinal disorders Vomiting 12.0
Musculoskeletal and connective tissue disorders Arthralgia 11.3
General disorders and administration site conditions Decreased appetite 11.3
Musculoskeletal and connective tissue disorders Musculoskeletal discomfort 11.3
Eye disorders Vision blurred 11.3
Musculoskeletal and connective tissue disorders Back pain 11.0
Investigations Body temperature increased 11.0
Nervous system disorders Confusional state 11.0
Gastrointestinal disorders Constipation 11.0
Gastrointestinal disorders Diarrhoea 11.0
Cardiac disorders Dizziness 11.0
General disorders and administration site conditions Feeling abnormal 11.0
General disorders and administration site conditions Gait disturbance 11.0
Nervous system disorders Hypoaesthesia 11.0
Nervous system disorders Loss of consciousness 11.0
Gastrointestinal disorders Nausea 11.0
Nervous system disorders Neuropathy peripheral 11.0
Blood and lymphatic system disorders Neutropenia 11.0
Cardiac disorders Oedema peripheral 11.0
General disorders and administration site conditions Pain 11.0
Nervous system disorders Peripheral sensory neuropathy 11.0
Nervous system disorders Reflexes abnormal 11.0
Vascular disorders Shock 11.0
Nervous system disorders Somnolence 11.0
Cardiac disorders Syncope 11.0
Blood and lymphatic system disorders Thrombocytopenia 11.0
Nervous system disorders Urinary incontinence 11.0
Eye disorders Vision blurred 11.0
Musculoskeletal and connective tissue disorders Musculoskeletal stiffness 10.9
Musculoskeletal and connective tissue disorders Nuchal rigidity 10.9
Psychiatric disorders Anxiety 10.7
Nervous system disorders Confusional state 10.7
Injury, poisoning and procedural complications Contusion 10.7
Ear and labyrinth disorders Deafness 10.7
General disorders and administration site conditions Decreased appetite 10.7
Metabolism and nutrition disorders Dehydration 10.7
Blood and lymphatic system disorders Diffuse large B-cell lymphoma 10.7
Cardiac disorders Dizziness 10.7
Gastrointestinal disorders Dysphagia 10.7
General disorders and administration site conditions Feeling abnormal 10.7
Gastrointestinal disorders Haemorrhoids 10.7
Hearing impaired 10.7
General disorders and administration site conditions Hyperhidrosis 10.7
Nervous system disorders Hypoaesthesia 10.7
Nervous system disorders Loss of consciousness 10.7
Musculoskeletal and connective tissue disorders Neck pain 10.7
Nervous system disorders Neuropathy peripheral 10.7
Nervous system disorders Peripheral sensory neuropathy 10.7
Investigations Platelet count decreased 10.7
Infections and infestations Pneumonia 10.7
Nervous system disorders Reflexes abnormal 10.7
Vascular disorders Shock 10.7
Cardiac disorders Syncope 10.7
Renal and urinary disorders Urinary retention 10.7
Cardiac disorders Oedema peripheral 10.5
Blood and lymphatic system disorders Thrombocytopenia 10.5
Nervous system disorders Agitation 10.1
Nervous system disorders Hypoaesthesia 10.1
Blood and lymphatic system disorders Neutropenia 10.1
Nervous system disorders Hypoaesthesia 10.0
Blood and lymphatic system disorders Thrombocytopenia 10.0
Cardiac disorders Dyspnoea 9.73
Nervous system disorders Muscular weakness 9.73
Musculoskeletal and connective tissue disorders Arthralgia 9.09
Respiratory, thoracic and mediastinal disorders Cough 9.09
Gastrointestinal disorders Dysphagia 9.09
Gastrointestinal disorders Incontinence 9.09
Musculoskeletal and connective tissue disorders Musculoskeletal discomfort 9.09
Nervous system disorders Neuropathy peripheral 9.09
General disorders and administration site conditions Pain 9.09
General disorders and administration site conditions Asthenia 9.0
Nervous system disorders Headache 9.0
Nervous system disorders Neuropathy peripheral 9.0
Blood and lymphatic system disorders Neutropenia 9.0
Nervous system disorders Tremor 9.0
Gastrointestinal disorders Abdominal pain 8.56
Gastrointestinal disorders Gastrointestinal pain 8.56
Cardiac disorders Tachycardia 8.56
Nervous system disorders Tremor 8.56
Psychiatric disorders Depression 8.17
Vascular disorders Hypotension 8.17
Blood and lymphatic system disorders Neutropenia 8.0
Blood and lymphatic system disorders Thrombocytopenia 8.0
Gastrointestinal disorders Dysphagia 7.78
Musculoskeletal and connective tissue disorders Neck pain 7.69
Gastrointestinal disorders Incontinence 7.39
Nervous system disorders Agitation 7.14
Endocrine disorders Hyperglycaemia 7.14
Metabolism and nutrition disorders Hypokalaemia 7.14
Vascular disorders Hypotension 7.14
General disorders and administration site conditions Mucosal inflammation 7.14
Nervous system disorders Muscular weakness 7.14
Musculoskeletal and connective tissue disorders Back pain 7.0
Nervous system disorders Confusional state 7.0
Gastrointestinal disorders Constipation 7.0
Convulsion 7.0
General disorders and administration site conditions Feeling abnormal 7.0
Metabolism and nutrition disorders Hyponatraemia 7.0
Cardiac disorders Oedema peripheral 7.0
Psychiatric disorders Anxiety 6.61
Respiratory, thoracic and mediastinal disorders Cough 6.61
Metabolism and nutrition disorders Hypokalaemia 6.61
Infections and infestations Pneumonia 6.23
Musculoskeletal and connective tissue disorders Musculoskeletal stiffness 6.06
Musculoskeletal and connective tissue disorders Nuchal rigidity 6.06
Nervous system disorders Peripheral sensory neuropathy 6.06
Infections and infestations Pneumonia 6.06
General disorders and administration site conditions Asthenia 6.0
Convulsion 6.0
General disorders and administration site conditions Fatigue 6.0
Nervous system disorders Peripheral sensory neuropathy 6.0
Ear and labyrinth disorders Deafness 5.84
Hearing impaired 5.84
Endocrine disorders Hyperglycaemia 5.84
Vascular disorders Hypertension 5.84
General disorders and administration site conditions Decreased appetite 5.45
Renal and urinary disorders Urinary retention 5.45
General disorders and administration site conditions Asthenia 5.0
Nervous system disorders Headache 5.0
Blood and lymphatic system disorders Thrombocytopenia 5.0
Blood and lymphatic system disorders Anaemia 4.0
Investigations Body temperature increased 4.0
Nervous system disorders Confusional state 4.0
Convulsion 4.0
General disorders and administration site conditions Feeling abnormal 4.0
General disorders and administration site conditions Gait disturbance 4.0
Nervous system disorders Memory impairment 4.0
Gastrointestinal disorders Nausea 4.0
Musculoskeletal and connective tissue disorders Neck pain 4.0
Nervous system disorders Neuropathy peripheral 4.0
Nervous system disorders Somnolence 4.0
Convulsion 3.57
Vascular disorders Hypertension 3.57
Metabolism and nutrition disorders Hyponatraemia 3.57
Nervous system disorders Memory impairment 3.57
Nervous system disorders Neuropathy peripheral 3.57
Nervous system disorders Neuropathy peripheral 3.5
Cardiac disorders Dizziness 3.11
Gastrointestinal disorders Haemorrhoids 3.11
Nervous system disorders Loss of consciousness 3.11
General disorders and administration site conditions Mucosal inflammation 3.11
Investigations Platelet count decreased 3.11
Vascular disorders Shock 3.11
Cardiac disorders Syncope 3.11
Psychiatric disorders Anxiety 3.03
Injury, poisoning and procedural complications Contusion 3.03
General disorders and administration site conditions Decreased appetite 3.03
Blood and lymphatic system disorders Diffuse large B-cell lymphoma 3.03
General disorders and administration site conditions Hyperhidrosis 3.03
General disorders and administration site conditions Oedema 3.03
Nervous system disorders Cauda equina syndrome 3.0
Nervous system disorders Cranial nerve paralysis 3.0
Ear and labyrinth disorders Deafness 3.0
Cardiac disorders Dizziness 3.0
Nervous system disorders Hypoaesthesia 3.0
Nervous system disorders Loss of consciousness 3.0
Musculoskeletal and connective tissue disorders Musculoskeletal stiffness 3.0
Nervous system disorders Neuropathy peripheral 3.0
Musculoskeletal and connective tissue disorders Nuchal rigidity 3.0
General disorders and administration site conditions Pain 3.0
Nervous system disorders Paraesthesia 3.0
Nervous system disorders Peripheral sensory neuropathy 3.0
Nervous system disorders Reflexes abnormal 3.0
Nervous system disorders Sensory loss 3.0
Vascular disorders Shock 3.0
Nervous system disorders Somnolence 3.0
Nervous system disorders Spinal cord disorder 3.0
Cardiac disorders Syncope 3.0
Nervous system disorders Urinary incontinence 3.0
Gastrointestinal disorders Vomiting 3.0
Nervous system disorders Neuropathy peripheral 2.72
Nervous system disorders Peripheral sensory neuropathy 2.72
Nervous system disorders Reflexes abnormal 2.72
Injury, poisoning and procedural complications Contusion 2.33
General disorders and administration site conditions Hyperhidrosis 2.33
General disorders and administration site conditions Oedema 2.33
Skin and subcutaneous tissue disorders Pruritus 2.33
Musculoskeletal and connective tissue disorders Back pain 2.0
Nervous system disorders Confusional state 2.0
General disorders and administration site conditions Feeling abnormal 2.0
General disorders and administration site conditions Gait disturbance 2.0
Nervous system disorders Headache 2.0
Nervous system disorders Hydrocephalus 2.0
Nervous system disorders Hypoaesthesia 2.0
Nervous system disorders Somnolence 2.0
Gastrointestinal disorders Vomiting 2.0
Musculoskeletal and connective tissue disorders Musculoskeletal stiffness 1.28
Musculoskeletal and connective tissue disorders Nuchal rigidity 1.28
Nervous system disorders Altered state of consciousness 1.0
Blood and lymphatic system disorders Anaemia 1.0
Eye disorders Blindness 1.0
Cardiac disorders Cardio-respiratory arrest 1.0
Convulsion 1.0
General disorders and administration site conditions Gait disturbance 1.0
Nervous system disorders Hemiplegia 1.0
Nervous system disorders Meningism 1.0
General disorders and administration site conditions Pain 1.0
Blood and lymphatic system disorders Diffuse large B-cell lymphoma 0.389

Adverse Reactions

System Organ Classification (SOC)
Relative Frequency (%)
Blood and lymphatic system disorders
14.0
Infections and infestations
12.61
General disorders and administration site conditions
11.88
Nervous system disorders
8.49
Respiratory, thoracic and mediastinal disorders
6.66
Gastrointestinal disorders
6.66
Vascular disorders
6.12
Injury, poisoning and procedural complications
4.18
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
4.11
Investigations
3.9
Metabolism and nutrition disorders
3.46
Cardiac disorders
3.26
Skin and subcutaneous tissue disorders
2.98
Hepatobiliary disorders
2.33

Cross References

Resources Reference
CAS NUMBER 147-94-4
ChEBI 28680
ChEMBL CHEMBL803
DrugBank DB00987
DrugCentral 770
EPA CompTox DTXSID3022877
FDA SRS 04079A1RDZ
Human Metabolome Database HMDB0000089
Guide to Pharmacology 4827
KEGG C02961
PDB AR3
PharmGKB PA449177
PubChem 6253
SureChEMBL SCHEMBL3140
ZINC ZINC000003795098