Trade Names: | |
Synonyms: | |
Status: | Approved (2015) |
Entry Type: | Antibody |
Molecule Category: | UNKNOWN |
ATC: | L01XC24 |
UNII: | 4Z63YK6E0E |
Action | Mechanism of Action | Reference |
---|---|---|
INHIBITOR | Lymphocyte differentiation antigen CD38 inhibitor | DailyMed |
Primary Target | |
---|---|
CD38 |
Mesh Heading | Maximum Phase | Mesh ID | Reference |
---|---|---|---|
Multiple Myeloma | 4 | D009101 | ClinicalTrials |
Neoplasms | 4 | D009369 | ClinicalTrials |
Amyloidosis | 3 | D000686 | ClinicalTrials |
Smoldering Multiple Myeloma | 3 | D000075122 | ClinicalTrials |
Paraproteinemias | 2 | D010265 | ClinicalTrials |
Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2 | D054198 | ClinicalTrials |
Leukemia, Myeloid, Acute | 2 | D015470 | ClinicalTrials |
Lymphoma, Large B-Cell, Diffuse | 2 | D016403 | ClinicalTrials |
Lymphoma, Mantle-Cell | 2 | D020522 | ClinicalTrials |
Colorectal Neoplasms | 2 | D015179 | ClinicalTrials |
Lupus Nephritis | 2 | D008181 | ClinicalTrials |
Amyloidosis, Familial | 2 | D028226 | ClinicalTrials |
Lymphoma | 2 | D008223 | ClinicalTrials |
Leukemia, Lymphocytic, Chronic, B-Cell | 2 | D015451 | ClinicalTrials |
Myelodysplastic Syndromes | 2 | D009190 | ClinicalTrials |
Waldenstrom Macroglobulinemia | 2 | D008258 | ClinicalTrials |
Alzheimer Disease | 2 | D000544 | ClinicalTrials |
Plasmacytoma | 2 | D010954 | ClinicalTrials |
Prostatic Neoplasms, Castration-Resistant | 2 | D064129 | ClinicalTrials |
Lupus Erythematosus, Systemic | 2 | D008180 | ClinicalTrials |
Purpura, Thrombocytopenic, Idiopathic | 2 | D016553 | ClinicalTrials |
POEMS Syndrome | 2 | D016878 | ClinicalTrials |
Lymphoma, Follicular | 2 | D008224 | ClinicalTrials |
Leukemia, Biphenotypic, Acute | 2 | D015456 | ClinicalTrials |
Graft vs Host Disease | 1 | D006086 | ClinicalTrials |
Prostatic Neoplasms | 1 | D011471 | ClinicalTrials |
Hodgkin Disease | 1 | D006689 | ClinicalTrials |
Lymphoma, Non-Hodgkin | 1 | D008228 | ClinicalTrials |
Leukemia, Plasma Cell | 1 | D007952 | ClinicalTrials |
Carcinoma, Non-Small-Cell Lung | 1 | D002289 | ClinicalTrials |
Mycosis Fungoides | 1 | D009182 | ClinicalTrials |
Glioblastoma | 1 | D005909 | ClinicalTrials |
Carcinoma, Renal Cell | 0 | D002292 | ClinicalTrials |
Resources | Reference |
---|---|
CAS NUMBER | 945721-28-8 |
ChEMBL | CHEMBL1743007 |
FDA SRS | 4Z63YK6E0E |
Guide to Pharmacology | 7395 |