DrugMapper


Trade Names:	DEXTROSE 10% IN PLASTIC CONTAINER DEXTROSE 20% IN PLASTIC CONTAINER DEXTROSE 25% DEXTROSE 2.5% IN PLASTIC CONTAINER DEXTROSE 30% IN PLASTIC CONTAINER DEXTROSE 38.5% IN PLASTIC CONTAINER DEXTROSE 40% IN PLASTIC CONTAINER DEXTROSE 50% DEXTROSE 50% IN PLASTIC CONTAINER DEXTROSE 5% IN PLASTIC CONTAINER DEXTROSE 60% DEXTROSE 60% IN PLASTIC CONTAINER DEXTROSE 70% IN PLASTIC CONTAINER DEXTROSE 7.7% IN PLASTIC CONTAINER
Synonyms:	Anhydrous dextrose Anhydrous glucose Capd Clintec Dextro energy Dextrogel Dextrose Dextrose anhydrous Dextrose, anhydrous Dextrose solution Dextrose, unspecified Dextrose, unspecified form D-glucose, anhydrous Gambrosol Glucose Glucose-40 Glucose anhydrous Glucose, anhydrous Glucose injection Glucose, liquid Glucose, unspecified form Grape sugar Gsf-syrup Insta-glucose Liquid glucose NSC-406891 Rapilose Yourgluco
Status:	Approved
Entry Type:	Small molecule
Molecule Category:	Parent
UNII:	IY9XDZ35W2


InChI Key	WQZGKKKJIJFFOK-VFUOTHLCSA-N
Smile	OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O
InChI	InChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6-/m1/s1

Property Name	Value
Molecular Formula	C6H12O6
Molecular Weight	180.16
AlogP	-3.22
Hydrogen Bond Acceptor	6.0
Hydrogen Bond Donor	5.0
Number of Rotational Bond	1.0
Polar Surface Area	110.38
Molecular species	NEUTRAL
Aromatic Rings	0.0
Heavy Atoms	12.0

Targets	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Enzyme Protease Serine protease Serine protease PA clan Serine protease S1A subfamily	-	-	-	-	28
Enzyme Transferase	-	-	-	-	36
Transporter Electrochemical transporter SLC superfamily of solute carriers SLC02 family of hexose and sugar alcohol transporters	-	-	-	-	74

Mesh Heading	Maximum Phase	Mesh ID	Reference
Hemorrhage	4	D006470	ClinicalTrials
Multiple Sclerosis	3	D009103	ClinicalTrials
Breast Neoplasms	3	D001943	ClinicalTrials
Myocardial Infarction	3	D009203	ClinicalTrials
Shock, Septic	3	D012772	ClinicalTrials
Neutropenia	3	D009503	ClinicalTrials
Angina, Unstable	3	D000789	ClinicalTrials
Renal Insufficiency, Chronic	3	D051436	ClinicalTrials
Ileus	3	D045823	ClinicalTrials
Liver Diseases	3	D008107	ClinicalTrials
Pain	3	D010146	ClinicalTrials
Heart Failure	3	D006333	ClinicalTrials
Carcinoma, Hepatocellular	3	D006528	ClinicalTrials
Hyponatremia	3	D007010	ClinicalTrials
Heart Failure	3	D006333	ClinicalTrials
Epilepsy	3	D004827	ClinicalTrials
Sepsis	3	D018805	ClinicalTrials
Postoperative Nausea and Vomiting	3	D020250	ClinicalTrials
Hearing Loss	2	D034381	ClinicalTrials
Obesity	2	D009765	ClinicalTrials
Schizophrenia	2	D012559	ClinicalTrials
Gastroparesis	2	D018589	ClinicalTrials
Amyotrophic Lateral Sclerosis	2	D000690	ClinicalTrials
Metabolic Diseases	2	D008659	ClinicalTrials
Osteoarthritis	2	D010003	ClinicalTrials
Vaginosis, Bacterial	2	D016585	ClinicalTrials
Hypospadias	2	D007021	ClinicalTrials
Common Cold	2	D003139	ClinicalTrials
Porphyrias	2	D011164	ClinicalTrials
Hyperlipidemias	2	D006949	ClinicalTrials
Malnutrition	2	D044342	ClinicalTrials
Postpartum Hemorrhage	2	D006473	ClinicalTrials
Tendinopathy	2	D052256	ClinicalTrials
Low Back Pain	2	D017116	ClinicalTrials
Temporomandibular Joint Disorders	2	D013705	ClinicalTrials
Hyperkalemia	2	D006947	ClinicalTrials
Biliary Tract Neoplasms	2	D001661	ClinicalTrials
Ischemic Stroke	2	D000083242	ClinicalTrials
Diabetes Mellitus, Type 2	1	D003924	ClinicalTrials
Pneumonia	1	D011014	ClinicalTrials
Diabetes Mellitus, Type 1	1	D003922	ClinicalTrials
Hypoglycemia	1	D007003	ClinicalTrials
Infections	1	D007239	ClinicalTrials
Mycoses	1	D009181	ClinicalTrials
Spinal Cord Injuries	1	D013119	ClinicalTrials
Brain Injuries	1	D001930	ClinicalTrials
Diabetes Mellitus	0	D003920	ClinicalTrials
Hypertension	0	D006973	ClinicalTrials

MCS

Target Level :

Level 3

Level 4

Level 5

Level 6

Extend :

Indication

Mechanism of Action

Primary Target

Target Level

Mixture

Adverse Reactions

SOC By Demographic Distribution

System Organ Classification (SOC)

	Relative Frequency (%)
General disorders and administration site conditions	17.33
Injury, poisoning and procedural complications	9.75
Nervous system disorders	8.14
Vascular disorders	7.52
Metabolism and nutrition disorders	7.15
Cardiac disorders	5.75
Skin and subcutaneous tissue disorders	5.74
Investigations	5.65
Respiratory, thoracic and mediastinal disorders	5.25
Gastrointestinal disorders	3.76
Blood and lymphatic system disorders	3.45
Musculoskeletal and connective tissue disorders	2.96
Immune system disorders	2.86
Endocrine disorders	2.76
Psychiatric disorders	2.73
Product issues	2.06

Resources	Reference
ChEBI	4167
ChEMBL	CHEMBL1222250
FDA SRS	IY9XDZ35W2
Human Metabolome Database	HMDB0000122
Guide to Pharmacology	4536
KEGG	C00031
SureChEMBL	SCHEMBL1278

DEXTROSE

Structure

Physicochemical Descriptors

Pharmacology

Indications

Related Entries

MCS

Adverse Reactions

Cross References


Active Pharmaceutical Ingredients (APIs) Scaffolds	Exact Similarity SubStructure	Threshold (%) >= 70