DINOPROST TROMETHAMINE

Search structure
Trade Names:
Synonyms:
Status: Approved (1982)
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: CT6BBQ5A68

Structure
InChI Key IYGXEHDCSOYNKY-RZHHZEQLSA-N
Smile CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)C[C@H](O)[C@@H]1C/C=C\CCCC(=O)O.NC(CO)(CO)CO
InChI
InChI=1S/C20H34O5.C4H11NO3/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25;5-4(1-6,2-7)3-8/h4,7,12-13,15-19,21-23H,2-3,5-6,8-11,14H2,1H3,(H,24,25);6-8H,1-3,5H2/b7-4-,13-12+;/t15-,16+,17+,18-,19+;/m0./s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C24H45NO8
Molecular Weight 475.62
AlogP 3.04
Hydrogen Bond Acceptor 4.0
Hydrogen Bond Donor 4.0
Number of Rotational Bond 12.0
Polar Surface Area 97.99
Molecular species ACID
Aromatic Rings 0.0
Heavy Atoms 25.0

Pharmacology

Action Mechanism of Action Reference
AGONIST Prostanoid FP receptor agonist ISBN
Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Transporter Primary active transporter ATP-binding cassette ABCC subfamily
- 7100 - - -

Related Entries

MCS

Cross References

Resources Reference
CAS NUMBER 38562-01-5
ChEBI 31502
ChEMBL CHEMBL1200896
DrugBank DB01160
FDA SRS CT6BBQ5A68
Guide to Pharmacology 1957
KEGG C12786
PharmGKB PA164781385
PubChem 5282415
SureChEMBL SCHEMBL203377
ZINC ZINC03830709
CONTENTS