| Trade Names: | |
| Synonyms: | |
| Status: | Approved (1996) |
| Entry Type: | Small molecule |
| Molecule Category: | Salt |
| UNII: | 3O2T2PJ89D |
| Parent Compound: | DONEPEZIL |
Structure
| InChI Key | XWAIAVWHZJNZQQ-UHFFFAOYSA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C24H30ClNO3 |
| Molecular Weight | 415.96 |
| AlogP | 4.36 |
| Hydrogen Bond Acceptor | 4.0 |
| Hydrogen Bond Donor | 0.0 |
| Number of Rotational Bond | 6.0 |
| Polar Surface Area | 38.77 |
| Molecular species | BASE |
| Aromatic Rings | 2.0 |
| Heavy Atoms | 28.0 |
Pharmacology
| Action | Mechanism of Action | Reference |
|---|---|---|
| INHIBITOR | Acetylcholinesterase inhibitor | DailyMed |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Alzheimer Disease | 4 | D000544 | ClinicalTrials |
| Depressive Disorder | 3 | D003866 | ClinicalTrials |
| Down Syndrome | 3 | D004314 | ClinicalTrials |
| Dementia, Vascular | 3 | D015140 | ClinicalTrials |
| Rett Syndrome | 3 | D015518 | ClinicalTrials |
| Delirium | 3 | D003693 | ClinicalTrials |
| Autistic Disorder | 2 | D001321 | ClinicalTrials |
| Migraine Disorders | 2 | D008881 | ClinicalTrials |
| Central Nervous System Neoplasms | 2 | D016543 | ClinicalTrials |
| Neuralgia | 2 | D009437 | ClinicalTrials |
| Cognitive Dysfunction | 1 | D060825 | ClinicalTrials |
Related Entries
Adverse Reactions
System Organ Classification (SOC)
Cross References
| Resources | Reference |
|---|---|
| ChEBI | 53292 |
| ChEMBL | CHEMBL1678 |
| EPA CompTox | DTXSID0046698 |
| FDA SRS | 3O2T2PJ89D |
| PDB | E20 |
| PubChem | 5741 |
| SureChEMBL | SCHEMBL1815 |
| ZINC | ZINC00897251 |
CONTENTS