Trade Names: | |
Synonyms: | |
Status: | Approved (1974) |
Entry Type: | Small molecule |
Molecule Category: | Salt |
UNII: | 7L3E358N9L |
Parent Compound: | DOPAMINE |
InChI Key | CTENFNNZBMHDDG-UHFFFAOYSA-N |
---|---|
Smile | |
InChI |
|
Property Name | Value |
---|---|
Molecular Formula | C8H12ClNO2 |
Molecular Weight | 189.64 |
AlogP | 0.6 |
Hydrogen Bond Acceptor | 3.0 |
Hydrogen Bond Donor | 3.0 |
Number of Rotational Bond | 2.0 |
Polar Surface Area | 66.48 |
Molecular species | BASE |
Aromatic Rings | 1.0 |
Heavy Atoms | 11.0 |
Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
---|---|---|---|---|---|---|
Membrane receptor
Family A G protein-coupled receptor
Small molecule receptor (family A GPCR)
Monoamine receptor
Dopamine receptor
|
1 | 1000-100000 | - | 2-11600 | - | |
Transporter
Electrochemical transporter
SLC superfamily of solute carriers
SLC21/SLCO family of organic anion transporting polypeptides
|
- | - | - | - | 67 |
Mesh Heading | Maximum Phase | Mesh ID | Reference |
---|---|---|---|
Parkinson Disease | 3 | D010300 | ClinicalTrials |
Resources | Reference |
---|---|
ChEBI | 4698 |
ChEMBL | CHEMBL1557 |
EPA CompTox | DTXSID7020550 |
FDA SRS | 7L3E358N9L |
Guide to Pharmacology | 940 |
KEGG | C03758 |
PDB | LDP |
PubChem | 65340 |
SureChEMBL | SCHEMBL40951 |
ZINC | ZINC00033882 |