| Trade Names: | |
| Synonyms: | |
| Status: | Approved (2017) |
| Entry Type: | Antibody |
| Molecule Category: | UNKNOWN |
| ATC: | D11AH05 |
| UNII: | 420K487FSG |
Pharmacology
| Action | Mechanism of Action | Reference |
|---|---|---|
| ANTAGONIST | Interleukin-4 receptor subunit alpha antagonist | PubMed |
| Primary Target | |
|---|---|
| Interleukin-4 receptor subunit α |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Nasal Polyps | 4 | D009298 | ClinicalTrials |
| Dermatitis, Atopic | 4 | D003876 | FDA |
| Urticaria | 3 | D014581 | ClinicalTrials |
| Eosinophilic Esophagitis | 3 | D057765 | ClinicalTrials |
| Pulmonary Disease, Chronic Obstructive | 3 | D029424 | ClinicalTrials |
| Aspergillosis, Allergic Bronchopulmonary | 3 | D001229 | ClinicalTrials |
| Dermatitis | 3 | D003872 | ClinicalTrials |
| Asthma | 3 | D001249 | ClinicalTrials |
| Sinusitis | 3 | D012852 | ClinicalTrials |
| Neurodermatitis | 3 | D009450 | ClinicalTrials |
| Severe Acute Respiratory Syndrome | 2 | D045169 | ClinicalTrials |
| Alopecia Areata | 2 | D000506 | ClinicalTrials |
| Respiratory Tract Diseases | 2 | D012140 | ClinicalTrials |
| Rhinitis, Allergic, Seasonal | 2 | D006255 | ClinicalTrials |
| Peanut Hypersensitivity | 2 | D021183 | ClinicalTrials |
| Angioedema | 2 | D000799 | ClinicalTrials |
| Conjunctivitis, Allergic | 2 | D003233 | ClinicalTrials |
| Pemphigoid, Bullous | 2 | D010391 | ClinicalTrials |
| Scleroderma, Localized | 2 | D012594 | ClinicalTrials |
| Pruritus | 2 | D011537 | ClinicalTrials |
| Prostatic Neoplasms, Castration-Resistant | 2 | D064129 | ClinicalTrials |
| Netherton Syndrome | 2 | D056770 | ClinicalTrials |
Adverse Reactions
System Organ Classification (SOC)
Cross References
| Resources | Reference |
|---|---|
| CAS NUMBER | 1190264-60-8 |
| ChEMBL | CHEMBL2108675 |
| FDA SRS | 420K487FSG |
| Guide to Pharmacology | 7574 |
CONTENTS