| Trade Names: | |
| Synonyms: | |
| Status: | Approved (2007) |
| Entry Type: | Antibody |
| Molecule Category: | UNKNOWN |
| ATC: | L04AA25 |
| UNII: | A3ULP0F556 |
Pharmacology
| Action | Mechanism of Action | Reference |
|---|---|---|
| INHIBITOR | Complement C5 inhibitor | DailyMed |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Atypical Hemolytic Uremic Syndrome | 4 | D065766 | ClinicalTrials |
| Hemoglobinuria, Paroxysmal | 4 | D006457 | ClinicalTrials |
| Myasthenia Gravis | 3 | D009157 | ClinicalTrials |
| Neuromyelitis Optica | 3 | D009471 | ClinicalTrials |
| Leukemia | 3 | D007938 | ClinicalTrials |
| Guillain-Barre Syndrome | 3 | D020275 | ClinicalTrials |
| Hemolytic-Uremic Syndrome | 3 | D006463 | ClinicalTrials |
| Thrombocytopenia | 2 | D013921 | ClinicalTrials |
| Macular Degeneration | 2 | D008268 | ClinicalTrials |
| Renal Insufficiency, Chronic | 2 | D051436 | ClinicalTrials |
| Diabetes Mellitus | 2 | D003920 | ClinicalTrials |
| Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis | 2 | D056648 | ClinicalTrials |
| Dermatomyositis | 2 | D003882 | ClinicalTrials |
| Severe Acute Respiratory Syndrome | 2 | D045169 | ClinicalTrials |
| Glomerulonephritis, Membranoproliferative | 1 | D015432 | ClinicalTrials |
| Graft vs Host Disease | 1 | D006086 | ClinicalTrials |
| Hemolysis | 1 | D006461 | ClinicalTrials |
| End Stage Liver Disease | 0 | D058625 | ClinicalTrials |
Adverse Reactions
System Organ Classification (SOC)
Cross References
| Resources | Reference |
|---|---|
| CAS NUMBER | 219685-50-4 |
| ChEMBL | CHEMBL1201828 |
| FDA SRS | A3ULP0F556 |
| Guide to Pharmacology | 6884 |
CONTENTS