| Trade Names: | |
| Synonyms: | |
| Status: | Approved (2012) |
| Entry Type: | Small molecule |
| Molecule Category: | Parent |
| ATC: | J05AJ02 |
| UNII: | 4GDQ854U53 |
Structure
| InChI Key | JUZYLCPPVHEVSV-LJQANCHMSA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C23H23ClFNO5 |
| Molecular Weight | 447.89 |
| AlogP | 4.28 |
| Hydrogen Bond Acceptor | 5.0 |
| Hydrogen Bond Donor | 2.0 |
| Number of Rotational Bond | 7.0 |
| Polar Surface Area | 88.76 |
| Molecular species | ACID |
| Aromatic Rings | 3.0 |
| Heavy Atoms | 31.0 |
Pharmacology
| Action | Mechanism of Action | Reference |
|---|---|---|
| INHIBITOR | Human immunodeficiency virus type 1 integrase inhibitor | DailyMed |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| HIV Infections | 4 | D015658 | ClinicalTrials |
| Acquired Immunodeficiency Syndrome | 3 | D000163 | ClinicalTrials |
| Insulin Resistance | 1 | D007333 | ClinicalTrials |
Related Entries
Side Effects from Label
Side Effects (PT)
| Side effects | Relative Frequency (%) | Labels | |
|---|---|---|---|
| Gastrointestinal disorders Diarrhoea | 7.1 | ||
| Gastrointestinal disorders Nausea | 4.0 |
Adverse Reactions
System Organ Classification (SOC)
Cross References
| Resources | Reference |
|---|---|
| CAS NUMBER | 697761-98-1 |
| ChEBI | 72289 |
| ChEMBL | CHEMBL204656 |
| DrugBank | DB09101 |
| DrugCentral | 4300 |
| FDA SRS | 4GDQ854U53 |
| PDB | ELV |
| PubChem | 5277135 |
| SureChEMBL | SCHEMBL726252 |
| ZINC | ZINC000013682481 |
CONTENTS