Trade Names: | |
Synonyms: | |
Status: | Approved (2001) |
Entry Type: | Small molecule |
Molecule Category: | Salt |
UNII: | 2T90KE67L0 |
Parent Compound: | ERTAPENEM |
InChI Key | ZXNAQFZBWUNWJM-HRXMHBOMSA-M |
---|---|
Smile | |
InChI |
|
Property Name | Value |
---|---|
Molecular Formula | C22H24N3NaO7S |
Molecular Weight | 497.51 |
AlogP | 0.94 |
Hydrogen Bond Acceptor | 7.0 |
Hydrogen Bond Donor | 5.0 |
Number of Rotational Bond | 7.0 |
Polar Surface Area | 156.27 |
Molecular species | ZWITTERION |
Aromatic Rings | 1.0 |
Heavy Atoms | 33.0 |
Action | Mechanism of Action | Reference |
---|---|---|
INHIBITOR | Bacterial penicillin-binding protein inhibitor | DailyMed |
Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
---|---|---|---|---|---|---|
Transporter
Primary active transporter
ATP-binding cassette
ABCC subfamily
|
- | 56200 | - | - | - |
Mesh Heading | Maximum Phase | Mesh ID | Reference |
---|---|---|---|
Infections | 4 | D007239 | ClinicalTrials |
Pneumonia | 3 | D011014 | ClinicalTrials |
Sepsis | 3 | D018805 | ClinicalTrials |
Diabetic Foot | 3 | D017719 | ClinicalTrials |
Urinary Tract Infections | 3 | D014552 | ClinicalTrials |
Resources | Reference |
---|---|
ChEBI | 60070 |
ChEMBL | CHEMBL1232 |
FDA SRS | 2T90KE67L0 |
PubChem | 11145493 |
SureChEMBL | SCHEMBL102761 |