Structure

InChI Key HTQBXNHDCUEHJF-XWLPCZSASA-N
Smile CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCSC)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(N)=O
InChI
InChI=1S/C184H282N50O60S/c1-16-94(10)147(178(289)213-114(52-58-144(257)258)163(274)218-121(73-101-77-195-105-39-24-23-38-103(101)105)168(279)215-116(68-90(2)3)165(276)205-107(41-26-28-61-186)158(269)219-122(75-134(189)243)154(265)198-79-135(244)196-83-139(248)231-63-30-43-129(231)175(286)225-127(87-238)174(285)223-125(85-236)155(266)200-80-136(245)202-96(12)181(292)233-65-32-45-131(233)183(294)234-66-33-46-132(234)182(293)232-64-31-44-130(232)176(287)222-124(84-235)150(190)261)229-170(281)119(71-99-34-19-17-20-35-99)217-166(277)117(69-91(4)5)214-159(270)108(42-29-62-194-184(191)192)212-177(288)146(93(8)9)228-151(262)95(11)203-156(267)111(49-55-141(251)252)208-161(272)112(50-56-142(253)254)209-162(273)113(51-57-143(255)256)210-164(275)115(59-67-295-15)211-160(271)110(47-53-133(188)242)207-157(268)106(40-25-27-60-185)206-172(283)126(86-237)224-167(278)118(70-92(6)7)216-169(280)123(76-145(259)260)220-173(284)128(88-239)226-180(291)149(98(14)241)230-171(282)120(72-100-36-21-18-22-37-100)221-179(290)148(97(13)240)227-138(247)82-199-153(264)109(48-54-140(249)250)204-137(246)81-197-152(263)104(187)74-102-78-193-89-201-102/h17-24,34-39,77-78,89-98,104,106-132,146-149,195,235-241H,16,25-33,40-76,79-88,185-187H2,1-15H3,(H2,188,242)(H2,189,243)(H2,190,261)(H,193,201)(H,196,244)(H,197,263)(H,198,265)(H,199,264)(H,200,266)(H,202,245)(H,203,267)(H,204,246)(H,205,276)(H,206,283)(H,207,268)(H,208,272)(H,209,273)(H,210,275)(H,211,271)(H,212,288)(H,213,289)(H,214,270)(H,215,279)(H,216,280)(H,217,277)(H,218,274)(H,219,269)(H,220,284)(H,221,290)(H,222,287)(H,223,285)(H,224,278)(H,225,286)(H,226,291)(H,227,247)(H,228,262)(H,229,281)(H,230,282)(H,249,250)(H,251,252)(H,253,254)(H,255,256)(H,257,258)(H,259,260)(H4,191,192,194)/t94-,95-,96-,97+,98+,104-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,146-,147-,148-,149-/m0/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C184H282N50O60S
Molecular Weight 4186.64
AlogP None
Hydrogen Bond Acceptor None
Hydrogen Bond Donor None
Number of Rotational Bond None
Polar Surface Area None
Molecular species None
Aromatic Rings None
Heavy Atoms None

Pharmacology

Action Mechanism of Action Reference
AGONIST Glucagon-like peptide 1 receptor agonist FDA

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Obesity 3 D009765 ClinicalTrials
Diabetes Mellitus, Type 1 3 D003922 ClinicalTrials
Parkinson Disease 3 D010300 ClinicalTrials
Myocardial Infarction 3 D009203 ClinicalTrials
Myocardial Infarction 3 D009203 ClinicalTrials
Weight Loss 3 D015431 ClinicalTrials
Coronary Disease 3 D003327 ClinicalTrials
Non-alcoholic Fatty Liver Disease 2 D065626 ClinicalTrials
Polycystic Ovary Syndrome 2 D011085 ClinicalTrials
Obesity, Morbid 2 D009767 ClinicalTrials
Multiple System Atrophy 2 D019578 ClinicalTrials
Hyperglycemia 2 D006943 ClinicalTrials
Stroke 2 D020521 ClinicalTrials
Alcoholism 2 D000437 ClinicalTrials
Prediabetic State 2 D011236 ClinicalTrials
Ischemic Stroke 2 D000083242 ClinicalTrials
Cocaine-Related Disorders 1 D019970 ClinicalTrials
Renal Insufficiency 1 D051437 ClinicalTrials
Smoking Cessation 1 D016540 ClinicalTrials
Nesidioblastosis 1 D046768 ClinicalTrials

Related Entries

Scaffolds

Side Effects from Label

Side effects Relative Frequency (%) Labels
Gastrointestinal disorders Nausea 44.0
Endocrine disorders Hypoglycaemia 43.5
Gastrointestinal disorders Nausea 41.0
Gastrointestinal disorders Nausea 40.0
Gastrointestinal disorders Nausea 35.0
Gastrointestinal disorders Nausea 34.5
Gastrointestinal disorders Nausea 33.8
Gastrointestinal disorders Nausea 27.0
Gastrointestinal disorders Nausea 24.4
Gastrointestinal disorders Diarrhoea 20.0
Gastrointestinal disorders Nausea 19.9
Endocrine disorders Hypoglycaemia 19.3
Gastrointestinal disorders Vomiting 18.6
General disorders and administration site conditions Injection site pruritus 18.2
Gastrointestinal disorders Diarrhoea 18.0
Gastrointestinal disorders Nausea
Gastrointestinal disorders Vomiting 18.0
Infections and infestations Nasopharyngitis 17.9
Infections and infestations Upper respiratory tract infection 17.2
Gastrointestinal disorders Diarrhoea 16.2
Endocrine disorders Hypoglycaemia 15.2
Gastrointestinal disorders Nausea
Nervous system disorders Headache 14.0
Gastrointestinal disorders Nausea 14.0
Endocrine disorders Hypoglycaemia 13.5
Gastrointestinal disorders Diarrhoea 13.1
Gastrointestinal disorders Diarrhoea 13.0
Gastrointestinal disorders Vomiting 13.0
Gastrointestinal disorders Nausea 12.9
Gastrointestinal disorders Diarrhoea 12.8
Gastrointestinal disorders Diarrhoea 12.6
Endocrine disorders Hypoglycaemia 12.6
Gastrointestinal disorders Diarrhoea 12.4
Nervous system disorders Headache 12.2
Gastrointestinal disorders Nausea 11.3
Gastrointestinal disorders Vomiting 11.3
General disorders and administration site conditions Injection site haematoma 11.0
Gastrointestinal disorders Diarrhoea 10.9
Gastrointestinal disorders Vomiting 10.8
General disorders and administration site conditions Injection site nodule 10.5
Infections and infestations Upper respiratory tract infection 10.3
General disorders and administration site conditions Injection site nodule 10.2
Gastrointestinal disorders Constipation 10.1
Gastrointestinal disorders Constipation 10.0
Nervous system disorders Headache 9.9
Gastrointestinal disorders Diarrhoea 9.64
Gastrointestinal disorders Nausea 9.64
Gastrointestinal disorders Diarrhoea 9.6
Gastrointestinal disorders Nausea 9.6
Gastrointestinal disorders Diarrhoea 9.4
Nervous system disorders Headache 9.4
Gastrointestinal disorders Diarrhoea 9.3
Nervous system disorders Headache 9.2
Nervous system disorders Headache 9.04
Endocrine disorders Hypoglycaemia 9.04
Infections and infestations Upper respiratory tract infection 9.04
Cardiac disorders Dizziness 9.0
General disorders and administration site conditions Feeling jittery 9.0
Nervous system disorders Headache 9.0
Gastrointestinal disorders Nausea 9.0
Psychiatric disorders Nervousness 9.0
Nervous system disorders Headache 8.97
Gastrointestinal disorders Viral diarrhoea 8.8
Gastrointestinal disorders Constipation 8.5
Nervous system disorders Headache 8.45
Infections and infestations Urinary tract infection 8.28
Nervous system disorders Headache 8.1
Gastrointestinal disorders Diarrhoea
Nervous system disorders Headache 8.0
Gastrointestinal disorders Nausea
Gastrointestinal disorders Nausea 8.0
Skin and subcutaneous tissue disorders Pruritus 8.0
General disorders and administration site conditions Injection site pruritus 7.94
Gastrointestinal disorders Vomiting 7.77
Nervous system disorders Headache 7.6
Gastrointestinal disorders Dyspepsia 7.4
Gastrointestinal disorders Gastrooesophageal reflux disease 7.4
General disorders and administration site conditions Injection site erythema 7.4
Gastrointestinal disorders Diarrhoea 7.3
Gastrointestinal disorders Dyspepsia 7.3
Gastrointestinal disorders Diarrhoea 7.27
Gastrointestinal disorders Dyspepsia 7.0
Endocrine disorders Hypoglycaemia 6.9
Gastrointestinal disorders Nausea 6.9
Infections and infestations Sinusitis 6.9
General disorders and administration site conditions Injection site nodule 6.7
Infections and infestations Sinusitis 6.67
Gastrointestinal disorders Constipation 6.3
Gastrointestinal disorders Constipation 6.21
Cardiac disorders Dizziness 6.21
Gastrointestinal disorders Constipation 6.2
General disorders and administration site conditions Asthenia 6.1
General disorders and administration site conditions Fatigue 6.1
Nervous system disorders Headache 6.1
Endocrine disorders Hypoglycaemia 6.06
Gastrointestinal disorders Diarrhoea
Gastrointestinal disorders Diarrhoea 6.0
Cardiac disorders Dizziness
Gastrointestinal disorders Dyspepsia 6.0
Nervous system disorders Headache
General disorders and administration site conditions Injection site nodule 6.0
Gastrointestinal disorders Constipation 5.74
General disorders and administration site conditions Asthenia 5.6
General disorders and administration site conditions Fatigue 5.6
Infections and infestations Nasopharyngitis 5.52
Gastrointestinal disorders Viral diarrhoea 5.52
Gastrointestinal disorders Diarrhoea 5.5
Nervous system disorders Headache 5.5
Gastrointestinal disorders Viral diarrhoea 5.5
Infections and infestations Urinary tract infection 5.42
General disorders and administration site conditions Injection site erythema 5.4
General disorders and administration site conditions Injection site haematoma 5.4
Gastrointestinal disorders Nausea 5.1
Infections and infestations Urinary tract infection 5.07
General disorders and administration site conditions Asthenia 5.0
General disorders and administration site conditions Decreased appetite 5.0
Gastrointestinal disorders Dyspepsia 5.0
General disorders and administration site conditions Injection site pruritus 5.0
Gastrointestinal disorders Vomiting 5.0
Gastrointestinal disorders Dyspepsia 4.9
Gastrointestinal disorders Nausea 4.85
Nervous system disorders Headache 4.83
Musculoskeletal and connective tissue disorders Arthralgia 4.82
Cardiac disorders Dizziness 4.82
General disorders and administration site conditions Injection site pruritus 4.82
Musculoskeletal and connective tissue disorders Musculoskeletal discomfort 4.82
Nervous system disorders Headache 4.8
General disorders and administration site conditions Injection site pruritus 4.8
Gastrointestinal disorders Nausea 4.8
Gastrointestinal disorders Nausea 4.3
Nervous system disorders Headache 4.24
Musculoskeletal and connective tissue disorders Back pain 4.22
Musculoskeletal and connective tissue disorders Arthralgia 4.14
Musculoskeletal and connective tissue disorders Back pain 4.14
Gastrointestinal disorders Gastrooesophageal reflux disease 4.14
Musculoskeletal and connective tissue disorders Musculoskeletal discomfort 4.14
Gastrointestinal disorders Diarrhoea 4.1
Gastrointestinal disorders Gastrooesophageal reflux disease 4.1
Musculoskeletal and connective tissue disorders Back pain 4.05
Gastrointestinal disorders Dyspepsia 4.05
General disorders and administration site conditions Injection site erythema 4.05
Gastrointestinal disorders Viral diarrhoea 4.04
Gastrointestinal disorders Abdominal distension 4.0
General disorders and administration site conditions Asthenia 4.0
Gastrointestinal disorders Diarrhoea 4.0
Skin and subcutaneous tissue disorders Erythema 4.0
General disorders and administration site conditions Feeling jittery
Nervous system disorders Headache
General disorders and administration site conditions Induration 4.0
Psychiatric disorders Nervousness
Gastrointestinal disorders Vomiting
Gastrointestinal disorders Vomiting 4.0
General disorders and administration site conditions Asthenia 3.89
General disorders and administration site conditions Fatigue 3.89
General disorders and administration site conditions Injection site induration 3.89
Infections and infestations Upper respiratory tract infection 3.89
Endocrine disorders Hypoglycaemia 3.72
Gastrointestinal disorders Diarrhoea 3.7
General disorders and administration site conditions Injection site nodule 3.7
Gastrointestinal disorders Nausea 3.7
Cardiac disorders Dizziness 3.64
Infections and infestations Urinary tract infection 3.64
Gastrointestinal disorders Abdominal pain 3.61
Gastrointestinal disorders Abdominal pain upper 3.61
Gastrointestinal disorders Dyspepsia 3.61
Gastrointestinal disorders Gastrointestinal pain 3.61
Gastrointestinal disorders Constipation 3.6
Gastrointestinal disorders Dyspepsia 3.6
Respiratory, thoracic and mediastinal disorders Cough 3.59
Gastrointestinal disorders Diarrhoea 3.59
Gastrointestinal disorders Oropharyngeal pain 3.59
Musculoskeletal and connective tissue disorders Arthralgia 3.55
Musculoskeletal and connective tissue disorders Musculoskeletal discomfort 3.55
General disorders and administration site conditions Procedural pain 3.45
General disorders and administration site conditions Asthenia 3.4
General disorders and administration site conditions Fatigue 3.4
Gastrointestinal disorders Constipation 3.3
Gastrointestinal disorders Dyspepsia 3.3
Gastrointestinal disorders Gastrooesophageal reflux disease 3.21
General disorders and administration site conditions Injection site nodule 3.21
Musculoskeletal and connective tissue disorders Back pain 3.14
Vascular disorders Hypertension 3.14
Infections and infestations Influenza 3.14
Musculoskeletal and connective tissue disorders Musculoskeletal pain 3.14
General disorders and administration site conditions Asthenia 3.03
Musculoskeletal and connective tissue disorders Back pain 3.03
Respiratory, thoracic and mediastinal disorders Cough 3.03
General disorders and administration site conditions Fatigue 3.03
Infections and infestations Influenza 3.03
Infections and infestations Nasopharyngitis 3.03
Gastrointestinal disorders Vomiting 3.03
Vascular disorders Hypertension 3.01
Endocrine disorders Hypoglycaemia 3.01
General disorders and administration site conditions Asthenia 3.0
General disorders and administration site conditions Decreased appetite 3.0
Gastrointestinal disorders Diarrhoea
Gastrointestinal disorders Dyspepsia
Gastrointestinal disorders Dyspepsia 3.0
General disorders and administration site conditions Fatigue 3.0
Gastrointestinal disorders Gastrooesophageal reflux disease 3.0
General disorders and administration site conditions Hyperhidrosis 3.0
General disorders and administration site conditions Nodule 3.0
Gastrointestinal disorders Vomiting 3.0
Gastrointestinal disorders Vomiting 2.9
Infections and infestations Sinusitis 2.87
Gastrointestinal disorders Viral diarrhoea 2.87
General disorders and administration site conditions Asthenia 2.76
Psychiatric disorders Depression 2.76
Gastrointestinal disorders Dyspepsia 2.76
Psychiatric disorders Erectile dysfunction 2.76
General disorders and administration site conditions Fatigue 2.76
Vascular disorders Hypertension 2.76
Metabolism and nutrition disorders Hypokalaemia 2.76
Nervous system disorders Insomnia 2.76
Vascular disorders Hypertension 2.7
Musculoskeletal and connective tissue disorders Arthralgia 2.69
Musculoskeletal and connective tissue disorders Musculoskeletal discomfort 2.69
General disorders and administration site conditions Decreased appetite 2.53
Cardiac disorders Dizziness 2.53
Gastrointestinal disorders Constipation 2.5
Gastrointestinal disorders Dyspepsia 2.42
General disorders and administration site conditions Injection site haematoma 2.42
Gastrointestinal disorders Toothache 2.42
General disorders and administration site conditions Injection site erythema 2.41
Infections and infestations Nasopharyngitis 2.41
Musculoskeletal and connective tissue disorders Pain in extremity 2.41
Gastrointestinal disorders Vomiting 2.41
Gastrointestinal disorders Dyspepsia 2.4
General disorders and administration site conditions Injection site erythema 2.4
Gastrointestinal disorders Vomiting 2.4
General disorders and administration site conditions Injection site haematoma 2.36
Infections and infestations Sinusitis 2.24
Gastrointestinal disorders Abdominal discomfort 2.2
Gastrointestinal disorders Abdominal pain 2.2
Gastrointestinal disorders Gastrointestinal pain 2.2
Infections and infestations Influenza 2.2
Musculoskeletal and connective tissue disorders Pain in extremity 2.2
Gastrointestinal disorders Dyspepsia 2.1
Gastrointestinal disorders Abdominal pain 2.07
Skin and subcutaneous tissue disorders Alopecia 2.07
Psychiatric disorders Anxiety 2.07
Musculoskeletal and connective tissue disorders Arthralgia 2.07
Endocrine disorders Diabetic neuropathy 2.07
Gastrointestinal disorders Gastrointestinal pain 2.07
Infections and infestations Influenza 2.07
General disorders and administration site conditions Injection site pain 2.07
Musculoskeletal and connective tissue disorders Muscle spasms 2.07
Musculoskeletal and connective tissue disorders Musculoskeletal discomfort 2.07
Gastrointestinal disorders Toothache 2.07
Gastrointestinal disorders Abdominal pain upper 2.03
General disorders and administration site conditions Decreased appetite 2.03
Gastrointestinal disorders Gastroenteritis 2.03
Gastrointestinal disorders Oropharyngeal pain 2.03
General disorders and administration site conditions Asthenia
Gastrointestinal disorders Constipation
Gastrointestinal disorders Dyspepsia
Gastrointestinal disorders Flatulence 2.0
Gastrointestinal disorders Gastrooesophageal reflux disease 2.0
Respiratory, thoracic and mediastinal disorders Cough 1.86
Musculoskeletal and connective tissue disorders Musculoskeletal pain 1.86
Musculoskeletal and connective tissue disorders Arthralgia 1.82
Musculoskeletal and connective tissue disorders Musculoskeletal discomfort 1.82
Musculoskeletal and connective tissue disorders Musculoskeletal pain 1.82
Gastrointestinal disorders Constipation 1.81
Psychiatric disorders Depression 1.81
Gastrointestinal disorders Gastroenteritis 1.81
Gastrointestinal disorders Constipation 1.8
Gastrointestinal disorders Dyspepsia 1.8
Gastrointestinal disorders Constipation 1.79
Gastrointestinal disorders Gastroenteritis 1.79
Gastrointestinal disorders Nausea 1.79
Gastrointestinal disorders Toothache 1.79
Endocrine disorders Hypoglycaemia 1.52
General disorders and administration site conditions Injection site pruritus 1.4
Gastrointestinal disorders Abdominal discomfort 1.38
Gastrointestinal disorders Abdominal pain upper 1.38
Respiratory, thoracic and mediastinal disorders Cough 1.38
General disorders and administration site conditions Injection site pruritus 1.38
Gastrointestinal disorders Oropharyngeal pain 1.38
Psychiatric disorders Anxiety 1.35
Cardiac disorders Dizziness 1.35
Infections and infestations Upper respiratory tract infection 1.35
Gastrointestinal disorders Vomiting 1.35
Gastrointestinal disorders Nausea 1.3
Gastrointestinal disorders Abdominal pain 1.21
Gastrointestinal disorders Abdominal pain upper 1.21
Gastrointestinal disorders Constipation 1.21
Gastrointestinal disorders Gastrointestinal pain 1.21
Gastrointestinal disorders Gastrooesophageal reflux disease 1.21
Vascular disorders Hypertension 1.21
General disorders and administration site conditions Injection site pruritus 1.21
Nervous system disorders Insomnia 1.21
Musculoskeletal and connective tissue disorders Pain in extremity 1.21
Psychiatric disorders Anxiety 1.2
Gastrointestinal disorders Constipation 1.2
Respiratory, thoracic and mediastinal disorders Cough 1.2
General disorders and administration site conditions Decreased appetite 1.2
Gastrointestinal disorders Gastrooesophageal reflux disease 1.2
Infections and infestations Influenza 1.2
General disorders and administration site conditions Injection site haematoma 1.2
General disorders and administration site conditions Injection site nodule 1.2
General disorders and administration site conditions Injection site pain 1.2
General disorders and administration site conditions Injection site pruritus 1.2
Musculoskeletal and connective tissue disorders Muscle spasms 1.2
Musculoskeletal and connective tissue disorders Musculoskeletal pain 1.2
Infections and infestations Sinusitis 1.2
Gastrointestinal disorders Toothache 1.2
Gastrointestinal disorders Viral diarrhoea 1.2
Psychiatric disorders Depression 1.01
General disorders and administration site conditions Injection site pain 1.01
Gastrointestinal disorders Toothache 1.01
Gastrointestinal disorders Abdominal distension
General disorders and administration site conditions Asthenia
Gastrointestinal disorders Dyspepsia
Gastrointestinal disorders Flatulence
Gastrointestinal disorders Gastrooesophageal reflux disease
General disorders and administration site conditions Hyperhidrosis
Gastrointestinal disorders Vomiting
Gastrointestinal disorders Vomiting 1.0
Gastrointestinal disorders Abdominal pain 0.897
Gastrointestinal disorders Abdominal pain upper 0.897
Gastrointestinal disorders Dyspepsia 0.897
Gastrointestinal disorders Gastrointestinal pain 0.897
Gastrointestinal disorders Gastrooesophageal reflux disease 0.897
General disorders and administration site conditions Injection site haematoma 0.897
Musculoskeletal and connective tissue disorders Pain in extremity 0.897
Psychiatric disorders Anxiety 0.845
Musculoskeletal and connective tissue disorders Muscle spasms 0.845
General disorders and administration site conditions Decreased appetite 0.69
Endocrine disorders Hypoglycaemia 0.69
Musculoskeletal and connective tissue disorders Pain in extremity 0.69
Nervous system disorders Insomnia 0.676
Psychiatric disorders Anxiety 0.606
Psychiatric disorders Erectile dysfunction 0.606
Gastrointestinal disorders Gastroenteritis 0.606
Endocrine disorders Hypoglycaemia 0.606
General disorders and administration site conditions Injection site induration 0.606
General disorders and administration site conditions Injection site nodule 0.606
Musculoskeletal and connective tissue disorders Muscle spasms 0.606
Gastrointestinal disorders Oropharyngeal pain 0.606
General disorders and administration site conditions Decreased appetite 0.602
Endocrine disorders Diabetic neuropathy 0.602
General disorders and administration site conditions Injection site induration 0.602
Nervous system disorders Insomnia 0.602
Gastrointestinal disorders Oropharyngeal pain 0.602
General disorders and administration site conditions Asthenia 0.6
General disorders and administration site conditions Fatigue 0.6
Musculoskeletal and connective tissue disorders Arthralgia 0.507
Metabolism and nutrition disorders Hypokalaemia 0.507
Musculoskeletal and connective tissue disorders Musculoskeletal discomfort 0.507
Gastrointestinal disorders Abdominal discomfort 0.448
General disorders and administration site conditions Asthenia 0.448
Psychiatric disorders Depression 0.448
General disorders and administration site conditions Fatigue 0.448
Endocrine disorders Hypoglycaemia 0.448
General disorders and administration site conditions Injection site erythema 0.448
General disorders and administration site conditions Injection site pain 0.448
General disorders and administration site conditions Injection site pruritus 0.448
Nervous system disorders Insomnia 0.448
Musculoskeletal and connective tissue disorders Muscle spasms 0.448
General disorders and administration site conditions Procedural pain 0.448
Infections and infestations Urinary tract infection 0.448
Endocrine disorders Diabetic neuropathy 0.338
Skin and subcutaneous tissue disorders Alopecia 0.169
Psychiatric disorders Erectile dysfunction 0.169
Endocrine disorders Hypoglycaemia 0.169
General disorders and administration site conditions Procedural pain 0.169

Adverse Reactions

System Organ Classification (SOC)
Relative Frequency (%)
Injury, poisoning and procedural complications
32.53
General disorders and administration site conditions
22.54
Product issues
11.44
Skin and subcutaneous tissue disorders
7.61
Vascular disorders
5.94
Investigations
4.2
Gastrointestinal disorders
3.7
Nervous system disorders
2.13

Cross References

Resources Reference
CAS NUMBER 141758-74-9
ChEMBL CHEMBL414357
DrugCentral 1123
FDA SRS 9P1872D4OL
SureChEMBL SCHEMBL14634818