Trade Names: | |
Synonyms: | |
Status: | Approved (2005) |
Entry Type: | Protein |
Molecule Category: | UNKNOWN |
ATC: | A10BJ01 |
UNII: | 9P1872D4OL |
InChI Key | HTQBXNHDCUEHJF-XWLPCZSASA-N |
---|---|
Smile | |
InChI |
|
Property Name | Value |
---|---|
Molecular Formula | C184H282N50O60S |
Molecular Weight | 4186.64 |
AlogP | None |
Hydrogen Bond Acceptor | None |
Hydrogen Bond Donor | None |
Number of Rotational Bond | None |
Polar Surface Area | None |
Molecular species | None |
Aromatic Rings | None |
Heavy Atoms | None |
Action | Mechanism of Action | Reference |
---|---|---|
AGONIST | Glucagon-like peptide 1 receptor agonist | FDA |
Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
---|---|---|---|---|---|---|
Membrane receptor
Family B G protein-coupled receptor
Peptide receptor (family B GPCR)
Glucagon-like receptor
Glucagon-like peptide receptor
|
0-0 | 1-6 | - | - | - |
Mesh Heading | Maximum Phase | Mesh ID | Reference |
---|---|---|---|
Obesity | 3 | D009765 | ClinicalTrials |
Diabetes Mellitus, Type 1 | 3 | D003922 | ClinicalTrials |
Parkinson Disease | 3 | D010300 | ClinicalTrials |
Myocardial Infarction | 3 | D009203 | ClinicalTrials |
Myocardial Infarction | 3 | D009203 | ClinicalTrials |
Weight Loss | 3 | D015431 | ClinicalTrials |
Coronary Disease | 3 | D003327 | ClinicalTrials |
Non-alcoholic Fatty Liver Disease | 2 | D065626 | ClinicalTrials |
Polycystic Ovary Syndrome | 2 | D011085 | ClinicalTrials |
Obesity, Morbid | 2 | D009767 | ClinicalTrials |
Multiple System Atrophy | 2 | D019578 | ClinicalTrials |
Hyperglycemia | 2 | D006943 | ClinicalTrials |
Stroke | 2 | D020521 | ClinicalTrials |
Alcoholism | 2 | D000437 | ClinicalTrials |
Prediabetic State | 2 | D011236 | ClinicalTrials |
Ischemic Stroke | 2 | D000083242 | ClinicalTrials |
Cocaine-Related Disorders | 1 | D019970 | ClinicalTrials |
Renal Insufficiency | 1 | D051437 | ClinicalTrials |
Smoking Cessation | 1 | D016540 | ClinicalTrials |
Nesidioblastosis | 1 | D046768 | ClinicalTrials |
Resources | Reference |
---|---|
CAS NUMBER | 141758-74-9 |
ChEMBL | CHEMBL414357 |
DrugCentral | 1123 |
FDA SRS | 9P1872D4OL |
SureChEMBL | SCHEMBL14634818 |