Trade Names: | |
Synonyms: | |
Status: | Approved (1982) |
Entry Type: | Small molecule |
Molecule Category: | UNKNOWN |
UNII: | Q3254X40X2 |
InChI Key | REEUVFCVXKWOFE-UHFFFAOYSA-K |
---|---|
Smile | |
InChI |
|
Property Name | Value |
---|---|
Molecular Formula | C30H60I3N3O3 |
Molecular Weight | 891.54 |
AlogP | 5.45 |
Hydrogen Bond Acceptor | 3.0 |
Hydrogen Bond Donor | 0.0 |
Number of Rotational Bond | 21.0 |
Polar Surface Area | 27.69 |
Molecular species | NEUTRAL |
Aromatic Rings | 1.0 |
Heavy Atoms | 36.0 |
Action | Mechanism of Action | Reference |
---|---|---|
ANTAGONIST | Muscle-type nicotinic acetylcholine receptor antagonist | ISBN |
Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
---|---|---|---|---|---|---|
Membrane receptor
Family A G protein-coupled receptor
Small molecule receptor (family A GPCR)
Monoamine receptor
Acetylcholine receptor
|
- | 776 | - | 468-3715 | - | |
Transporter
Electrochemical transporter
SLC superfamily of solute carriers
SLC21/SLCO family of organic anion transporting polypeptides
|
- | - | - | - | 79 |
Resources | Reference |
---|---|
CAS NUMBER | 65-29-2 |
ChEMBL | CHEMBL1200993 |
DrugBank | DB00483 |
EPA CompTox | DTXSID5023089 |
FDA SRS | Q3254X40X2 |
Guide to Pharmacology | 356 |
PDB | GMN |
PubChem | 6172 |
SureChEMBL | SCHEMBL249090 |
ZINC | ZINC03830882 |