Trade Names: | |
Synonyms: | |
Status: | Approved (1993) |
Entry Type: | Small molecule |
Molecule Category: | Salt |
UNII: | 318F6L70J8 |
Parent Compound: | GRANISETRON |
InChI Key | QYZRTBKYBJRGJB-UHFFFAOYSA-N |
---|---|
Smile | |
InChI |
|
Property Name | Value |
---|---|
Molecular Formula | C18H25ClN4O |
Molecular Weight | 348.88 |
AlogP | 2.32 |
Hydrogen Bond Acceptor | 4.0 |
Hydrogen Bond Donor | 1.0 |
Number of Rotational Bond | 2.0 |
Polar Surface Area | 50.16 |
Molecular species | BASE |
Aromatic Rings | 2.0 |
Heavy Atoms | 23.0 |
Action | Mechanism of Action | Reference |
---|---|---|
ANTAGONIST | Serotonin 3a (5-HT3a) receptor antagonist | DailyMed |
Mesh Heading | Maximum Phase | Mesh ID | Reference |
---|---|---|---|
Nausea | 4 | D009325 | ClinicalTrials |
Nausea | 4 | D009325 | ClinicalTrials |
Postoperative Nausea and Vomiting | 4 | D020250 | ClinicalTrials |
Neoplasms | 3 | D009369 | ClinicalTrials |
Sepsis | 2 | D018805 | ClinicalTrials |
Resources | Reference |
---|---|
ChEMBL | CHEMBL1237080 |
FDA SRS | 318F6L70J8 |
PubChem | 6918003 |
SureChEMBL | SCHEMBL33433 |