HYDROXYAMPHETAMINE HYDROBROMIDE

Search structure


Trade Names:	PAREDRINE
Synonyms:	Hydroxyamfetamine hbr Hydroxyamfetamine hydrobromide Hydroxyamphetamine hbr Hydroxyamphetamine hydrobromide Hyroxyamfetamine hydrobromide NSC-61065 Oxamphetamine hydrobromide Paredrine Phenol, 4-(2-aminopropyl)-, hbr
Status:	Approved (1969)
Entry Type:	Small molecule
Molecule Category:	Parent
UNII:	59IG47SZ0E

Structure


InChI Key	RZCJLMTXBMNRAD-UHFFFAOYSA-N
Smile	Br.CC(N)Cc1ccc(O)cc1
InChI	InChI=1S/C9H13NO.BrH/c1-7(10)6-8-2-4-9(11)5-3-8;/h2-5,7,11H,6,10H2,1H3;1H

Physicochemical Descriptors

Property Name	Value
Molecular Formula	C9H14BrNO
Molecular Weight	232.12
AlogP	1.28
Hydrogen Bond Acceptor	2.0
Hydrogen Bond Donor	2.0
Number of Rotational Bond	2.0
Polar Surface Area	46.25
Molecular species	BASE
Aromatic Rings	1.0
Heavy Atoms	11.0

Pharmacology

Action	Mechanism of Action	Reference
AGONIST	Adrenergic receptor agonist	PubMed PubMed PubMed PubMed DailyMed

Targets	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Transporter Electrochemical transporter SLC superfamily of solute carriers SLC21/SLCO family of organic anion transporting polypeptides	-	-	-	-	84

Related Entries

Mixture

Adverse Reactions

SOC By Demographic Distribution

System Organ Classification (SOC)

	Relative Frequency (%)
General disorders and administration site conditions	25.0
Endocrine disorders	12.5
Hepatobiliary disorders	12.5
Injury, poisoning and procedural complications	12.5
Investigations	12.5
Metabolism and nutrition disorders	12.5
Renal and urinary disorders	12.5

Cross References

Resources	Reference
ChEMBL	CHEMBL1200705
EPA CompTox	DTXSID0045961
FDA SRS	59IG47SZ0E
PubChem	9377
SureChEMBL	SCHEMBL221647
ZINC	ZINC01690604

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