Trade Names:
Synonyms:
Status: Approved (2018)
Entry Type: Oligonucleotide
Molecule Category: Salt
UNII: 950736UC77
Parent Compound: INOTERSEN

Pharmacology

Action Mechanism of Action Reference
ANTISENSE INHIBITOR Transthyretin mRNA antisense inhibitor FDA

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Amyloid Neuropathies, Familial 4 D028227 FDA

Related Entries

Parent

Adverse Reactions

System Organ Classification (SOC)
Relative Frequency (%)
Cardiac disorders
17.65
General disorders and administration site conditions
14.71
Respiratory, thoracic and mediastinal disorders
8.82
Vascular disorders
8.82
Infections and infestations
7.35
Investigations
7.35
Gastrointestinal disorders
5.88
Metabolism and nutrition disorders
4.41
Nervous system disorders
4.41
Endocrine disorders
2.94
Musculoskeletal and connective tissue disorders
2.94
Renal and urinary disorders
2.94
Skin and subcutaneous tissue disorders
2.94
Surgical and medical procedures
2.94

Cross References

Resources Reference
ChEMBL CHEMBL4297537
FDA SRS 950736UC77
PubChem 121493436