| Trade Names: | |
| Synonyms: | |
| Status: | Approved (1956) |
| Entry Type: | Small molecule |
| Molecule Category: | Salt |
| UNII: | DIA2A74855 |
| Parent Compound: | ISOPROTERENOL |
Structure
| InChI Key | IROWCYIEJAOFOW-UHFFFAOYSA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C11H18ClNO3 |
| Molecular Weight | 247.72 |
| AlogP | 1.13 |
| Hydrogen Bond Acceptor | 4.0 |
| Hydrogen Bond Donor | 4.0 |
| Number of Rotational Bond | 4.0 |
| Polar Surface Area | 72.72 |
| Molecular species | BASE |
| Aromatic Rings | 1.0 |
| Heavy Atoms | 15.0 |
Pharmacology
| Action | Mechanism of Action | Reference |
|---|---|---|
| AGONIST | Adrenergic receptor beta agonist | FDA |
| Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
|---|---|---|---|---|---|---|
|
Membrane receptor
Family A G protein-coupled receptor
Small molecule receptor (family A GPCR)
Monoamine receptor
Adrenergic receptor
|
0-240 | - | - | 501-501 | - | |
|
Transporter
Electrochemical transporter
SLC superfamily of solute carriers
SLC21/SLCO family of organic anion transporting polypeptides
|
- | - | - | - | 105 |
Indications
Related Entries
Adverse Reactions
System Organ Classification (SOC)
Cross References
| Resources | Reference |
|---|---|
| ChEBI | 31453 |
| ChEMBL | CHEMBL1711 |
| EPA CompTox | DTXSID6025486 |
| FDA SRS | DIA2A74855 |
| Guide to Pharmacology | 548 |
| KEGG | D00235 |
| PDB | 2TN |
| PubChem | 5807 |
| SureChEMBL | SCHEMBL7627 |
| ZINC | ZINC00113415 |
CONTENTS