Trade Names: | |
Synonyms: | |
Status: | Approved (1996) |
Entry Type: | Small molecule |
Molecule Category: | Parent Prodrug |
ATC: | S01EE01 |
UNII: | 6Z5B6HVF6O |
InChI Key | GGXICVAJURFBLW-CEYXHVGTSA-N |
---|---|
Smile | |
InChI |
|
Property Name | Value |
---|---|
Molecular Formula | C26H40O5 |
Molecular Weight | 432.6 |
AlogP | 4.19 |
Hydrogen Bond Acceptor | 5.0 |
Hydrogen Bond Donor | 3.0 |
Number of Rotational Bond | 13.0 |
Polar Surface Area | 86.99 |
Molecular species | NEUTRAL |
Aromatic Rings | 1.0 |
Heavy Atoms | 31.0 |
Action | Mechanism of Action | Reference |
---|---|---|
AGONIST | Prostanoid FP receptor agonist | FDA |
Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
---|---|---|---|---|---|---|
Ion channel
Other ion channel
Pore-forming toxins (proteins and peptides)
|
- | - | - | - | 11 | |
Transporter
Primary active transporter
ATP-binding cassette
ABCB subfamily
|
- | 12900 | - | - | - |
Mesh Heading | Maximum Phase | Mesh ID | Reference |
---|---|---|---|
Meniere Disease | 2 | D008575 | ClinicalTrials |
Vitiligo | 2 | D014820 | ClinicalTrials |
Resources | Reference |
---|---|
CAS NUMBER | 130209-82-4 |
ChEBI | 6384 |
ChEMBL | CHEMBL1051 |
DrugBank | DB00654 |
DrugCentral | 1551 |
EPA CompTox | DTXSID1041057 |
FDA SRS | 6Z5B6HVF6O |
Human Metabolome Database | HMDB0014792 |
Guide to Pharmacology | 1961 |
KEGG | D00356 |
PubChem | 5311221 |
SureChEMBL | SCHEMBL24698 |
ZINC | ZINC000012468792 |