Trade Names: | |
Synonyms: | |
Status: | Approved (1985) |
Entry Type: | Protein |
Molecule Category: | Salt |
UNII: | 37JNS02E7V |
Parent Compound: | LEUPROLIDE |
InChI Key | RGLRXNKKBLIBQS-XNHQSDQCSA-N |
---|---|
Smile | |
InChI |
|
Property Name | Value |
---|---|
Molecular Formula | C61H88N16O14 |
Molecular Weight | 1269.47 |
AlogP | None |
Hydrogen Bond Acceptor | None |
Hydrogen Bond Donor | None |
Number of Rotational Bond | None |
Polar Surface Area | None |
Molecular species | None |
Aromatic Rings | None |
Heavy Atoms | None |
Action | Mechanism of Action | Reference |
---|---|---|
AGONIST | Gonadotropin-releasing hormone receptor agonist | FDA |
Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
---|---|---|---|---|---|---|
Transporter
Primary active transporter
ATP-binding cassette
ABCC subfamily
|
- | 80200 | - | - | - |
Mesh Heading | Maximum Phase | Mesh ID | Reference |
---|---|---|---|
Prostatic Neoplasms | 4 | D011471 | ClinicalTrials |
Puberty, Precocious | 4 | D011629 | ClinicalTrials |
Prostatic Neoplasms | 4 | D011471 | ClinicalTrials |
Prostatic Neoplasms, Castration-Resistant | 4 | D064129 | ClinicalTrials |
Puberty, Precocious | 4 | D011629 | ClinicalTrials |
Infertility, Male | 3 | D007248 | ClinicalTrials |
Leiomyoma | 3 | D007889 | ClinicalTrials |
Obesity | 3 | D009765 | ClinicalTrials |
Breast Neoplasms | 3 | D001943 | ClinicalTrials |
Endometriosis | 3 | D004715 | ClinicalTrials |
Neoplasms | 3 | D009369 | ClinicalTrials |
Breast Neoplasms | 3 | D001943 | ClinicalTrials |
Alzheimer Disease | 2 | D000544 | ClinicalTrials |
Multiple Myeloma | 2 | D009101 | ClinicalTrials |
Lymphoma, Mantle-Cell | 2 | D020522 | ClinicalTrials |
Depression, Postpartum | 2 | D019052 | ClinicalTrials |
Bulimia Nervosa | 2 | D052018 | ClinicalTrials |
Cognitive Dysfunction | 2 | D060825 | ClinicalTrials |
Hodgkin Disease | 2 | D006689 | ClinicalTrials |
Hypertension | 0 | D006973 | ClinicalTrials |
Resources | Reference |
---|---|
ChEBI | 63597 |
ChEMBL | CHEMBL1200775 |
EPA CompTox | DTXSID7049009 |
FDA SRS | 37JNS02E7V |
PubChem | 657180 |
SureChEMBL | SCHEMBL3174 |