LUTETIUM DOTATATE LU-177

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Trade Names:
Synonyms:
Status: Approved (2018)
Entry Type: Unknown
Molecule Category: UNKNOWN
UNII: AE221IM3BB

Physicochemical Descriptors

Property Name Value
Molecular Formula C65H90LuN14O19S2
Molecular Weight 1612.59
AlogP None
Hydrogen Bond Acceptor None
Hydrogen Bond Donor None
Number of Rotational Bond None
Polar Surface Area None
Molecular species None
Aromatic Rings None
Heavy Atoms None

Pharmacology

Action Mechanism of Action Reference
BINDING AGENT Somatostatin receptor binding agent FDA

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Neuroendocrine Tumors 4 D018358 ClinicalTrials
Neuroendocrine Tumors 4 D018358 ClinicalTrials
Carcinoid Tumor 3 D002276 ClinicalTrials
Carcinoma, Neuroendocrine 2 D018278 ClinicalTrials
Meningioma 2 D008579 ClinicalTrials
Neuroblastoma 2 D009447 ClinicalTrials
Breast Neoplasms 2 D001943 ClinicalTrials

Adverse Reactions

SOC By Demographic Distribution
System Organ Classification (SOC)
Relative Frequency (%)
Gastrointestinal disorders
19.35
General disorders and administration site conditions
16.94
Skin and subcutaneous tissue disorders
10.48
Injury, poisoning and procedural complications
7.26
Metabolism and nutrition disorders
7.26
Cardiac disorders
5.65
Hepatobiliary disorders
5.65
Nervous system disorders
4.84
Vascular disorders
4.84
Investigations
4.03
Reproductive system and breast disorders
4.03
Musculoskeletal and connective tissue disorders
3.23

Cross References

Resources Reference
ChEMBL CHEMBL3989924
FDA SRS AE221IM3BB
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