Trade Names: | |
Synonyms: | |
Status: | Approved (1959) |
Entry Type: | Small molecule |
Molecule Category: | Parent |
UNII: | C2QI4IOI2G |
Parent Compound: | MEDROXYPROGESTERONE |
InChI Key | PSGAAPLEWMOORI-PEINSRQWSA-N |
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Smile | |
InChI |
|
Property Name | Value |
---|---|
Molecular Formula | C24H34O4 |
Molecular Weight | 386.53 |
AlogP | 4.66 |
Hydrogen Bond Acceptor | 4.0 |
Hydrogen Bond Donor | 0.0 |
Number of Rotational Bond | 2.0 |
Polar Surface Area | 60.44 |
Molecular species | NEUTRAL |
Aromatic Rings | 0.0 |
Heavy Atoms | 28.0 |
Action | Mechanism of Action | Reference |
---|---|---|
AGONIST | Progesterone receptor agonist | DailyMed |
Mesh Heading | Maximum Phase | Mesh ID | Reference |
---|---|---|---|
Hemorrhage | 4 | D006470 | ClinicalTrials |
Carcinoma, Renal Cell | 4 | D002292 | ClinicalTrials |
Infertility | 3 | D007246 | ClinicalTrials |
Hypertension | 3 | D006973 | ClinicalTrials |
Myocardial Ischemia | 3 | D017202 | ClinicalTrials |
Hypercholesterolemia | 3 | D006937 | ClinicalTrials |
Hot Flashes | 3 | D019584 | ClinicalTrials |
Thrombosis | 3 | D013927 | ClinicalTrials |
Menopause | 3 | D008593 | ClinicalTrials |
Kidney Neoplasms | 3 | D007680 | ClinicalTrials |
Endometrial Neoplasms | 3 | D016889 | ClinicalTrials |
Prostatic Neoplasms | 3 | D011471 | ClinicalTrials |
Coronary Disease | 3 | D003327 | ClinicalTrials |
Lupus Erythematosus, Systemic | 3 | D008180 | ClinicalTrials |
Heart Diseases | 3 | D006331 | ClinicalTrials |
Osteoporosis | 3 | D010024 | ClinicalTrials |
Menorrhagia | 3 | D008595 | ClinicalTrials |
Turner Syndrome | 3 | D014424 | ClinicalTrials |
Diabetes Mellitus | 3 | D003920 | ClinicalTrials |
Alzheimer Disease | 2 | D000544 | ClinicalTrials |
Sleep Apnea Syndromes | 2 | D012891 | ClinicalTrials |
Endometrial Hyperplasia | 2 | D004714 | ClinicalTrials |
HIV Infections | 2 | D015658 | ClinicalTrials |
Primary Ovarian Insufficiency | 2 | D016649 | ClinicalTrials |
HIV Infections | 2 | D015658 | ClinicalTrials |
Pain | 2 | D010146 | ClinicalTrials |
Pregnancy | 1 | D011247 | ClinicalTrials |
Resources | Reference |
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CAS NUMBER | 71-58-9 |
ChEBI | 6716 |
ChEMBL | CHEMBL717 |
DrugBank | DB00603 |
DrugCentral | 1659 |
EPA CompTox | DTXSID0025527 |
FDA SRS | C2QI4IOI2G |
KEGG | C08150 |
PubChem | 6279 |
SureChEMBL | SCHEMBL4276 |
ZINC | ZINC000005029557 |