MEPERIDINE HYDROCHLORIDE

Search structure
Trade Names:
Synonyms:
Status: Approved (1942)
Entry Type: Small molecule
Molecule Category: Salt
UNII: N8E7F7Q170
Parent Compound: MEPERIDINE

Structure
InChI Key WCNLCIJMFAJCPX-UHFFFAOYSA-N
Smile CCOC(=O)C1(c2ccccc2)CCN(C)CC1.Cl
InChI
InChI=1S/C15H21NO2.ClH/c1-3-18-14(17)15(9-11-16(2)12-10-15)13-7-5-4-6-8-13;/h4-8H,3,9-12H2,1-2H3;1H

Physicochemical Descriptors

Property Name Value
Molecular Formula C15H22ClNO2
Molecular Weight 283.8
AlogP 2.21
Hydrogen Bond Acceptor 3.0
Hydrogen Bond Donor 0.0
Number of Rotational Bond 3.0
Polar Surface Area 29.54
Molecular species NEUTRAL
Aromatic Rings 1.0
Heavy Atoms 18.0

Pharmacology

Action Mechanism of Action Reference
AGONIST Mu opioid receptor agonist PubMed
Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Membrane receptor Family A G protein-coupled receptor Peptide receptor (family A GPCR) Short peptide receptor (family A GPCR) Opioid receptor
- 10000 - 920-920 -
Transporter Electrochemical transporter SLC superfamily of solute carriers SLC06 neurotransmitter transporter family
- 610-12600 - 17800-17800 22

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Hypotension 2 D007022 ClinicalTrials

Related Entries

Parent
Mixture
Mixture

Adverse Reactions

SOC By Demographic Distribution
System Organ Classification (SOC)
Relative Frequency (%)
Immune system disorders
36.24
Gastrointestinal disorders
8.44
General disorders and administration site conditions
8.39
Nervous system disorders
8.0
Psychiatric disorders
6.2
Skin and subcutaneous tissue disorders
5.86
Vascular disorders
3.89
Respiratory, thoracic and mediastinal disorders
3.6
Injury, poisoning and procedural complications
3.54
Cardiac disorders
3.24
Musculoskeletal and connective tissue disorders
2.61

Cross References

Resources Reference
ChEBI 31984
ChEMBL CHEMBL1701
FDA SRS N8E7F7Q170
PubChem 5750
SureChEMBL SCHEMBL41046
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