Trade Names: | |
Synonyms: | |
Status: | Approved (1995) |
Entry Type: | Small molecule |
Molecule Category: | Salt |
UNII: | 786Z46389E |
Parent Compound: | METFORMIN |
InChI Key | OETHQSJEHLVLGH-UHFFFAOYSA-N |
---|---|
Smile | |
InChI |
|
Property Name | Value |
---|---|
Molecular Formula | C4H12ClN5 |
Molecular Weight | 165.63 |
AlogP | -1.03 |
Hydrogen Bond Acceptor | 2.0 |
Hydrogen Bond Donor | 4.0 |
Number of Rotational Bond | 0.0 |
Polar Surface Area | 88.99 |
Molecular species | BASE |
Aromatic Rings | 0.0 |
Heavy Atoms | 9.0 |
Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
---|---|---|---|---|---|---|
Transporter
Electrochemical transporter
SLC superfamily of solute carriers
SLC21/SLCO family of organic anion transporting polypeptides
|
- | - | - | - | 104 |
Mesh Heading | Maximum Phase | Mesh ID | Reference |
---|---|---|---|
Diabetes Mellitus | 4 | D003920 | ClinicalTrials |
Renal Insufficiency, Chronic | 3 | D051436 | ClinicalTrials |
Metabolic Syndrome | 3 | D024821 | ClinicalTrials |
Diabetes, Gestational | 3 | D016640 | ClinicalTrials |
Breast Neoplasms | 3 | D001943 | ClinicalTrials |
Diabetic Foot | 2 | D017719 | ClinicalTrials |
Lung Neoplasms | 2 | D008175 | ClinicalTrials |
Carcinoma, Pancreatic Ductal | 2 | D021441 | ClinicalTrials |
Carcinoma, Non-Small-Cell Lung | 2 | D002289 | ClinicalTrials |
Heart Failure | 2 | D006333 | ClinicalTrials |
Peritoneal Neoplasms | 2 | D010534 | ClinicalTrials |
Fallopian Tube Neoplasms | 2 | D005185 | ClinicalTrials |
Endometrial Neoplasms | 2 | D016889 | ClinicalTrials |
Prostatic Neoplasms, Castration-Resistant | 2 | D064129 | ClinicalTrials |
Colonic Neoplasms | 2 | D003110 | ClinicalTrials |
Squamous Cell Carcinoma of Head and Neck | 2 | D000077195 | ClinicalTrials |
Prostatic Neoplasms | 2 | D011471 | ClinicalTrials |
Prostatic Neoplasms | 2 | D011471 | ClinicalTrials |
Fanconi Anemia | 2 | D005199 | ClinicalTrials |
Carcinoma, Endometrioid | 2 | D018269 | ClinicalTrials |
Adenocarcinoma of Lung | 2 | D000077192 | ClinicalTrials |
Obesity | 2 | D009765 | ClinicalTrials |
Pleural Effusion | 2 | D010996 | ClinicalTrials |
Ascites | 2 | D001201 | ClinicalTrials |
Cystadenoma, Serous | 2 | D018293 | ClinicalTrials |
Hyperinsulinism | 2 | D006946 | ClinicalTrials |
Stargardt Disease | 1 | D000080362 | ClinicalTrials |
Multiple Myeloma | 1 | D009101 | ClinicalTrials |
Diabetic Neuropathies | 1 | D003929 | ClinicalTrials |
Gliosarcoma | 1 | D018316 | ClinicalTrials |
Pancreatic Neoplasms | 1 | D010190 | ClinicalTrials |
Inflammation | 1 | D007249 | ClinicalTrials |
Head and Neck Neoplasms | 0 | D006258 | ClinicalTrials |
Polycystic Ovary Syndrome | 0 | D011085 | ClinicalTrials |
Resources | Reference |
---|---|
ChEBI | 6802 |
ChEMBL | CHEMBL1703 |
EPA CompTox | DTXSID9037246 |
FDA SRS | 786Z46389E |
KEGG | C07670 |
PubChem | 14219 |
SureChEMBL | SCHEMBL20140191 |
ZINC | ZINC03798537 |