Trade Names: | |
Synonyms: | |
Status: | Approved (1978) |
Entry Type: | Small molecule |
Molecule Category: | Salt |
UNII: | W5S57Y3A5L |
Parent Compound: | METOPROLOL |
InChI Key | YGULWPYYGQCFMP-UHFFFAOYSA-N |
---|---|
Smile | |
InChI |
|
Property Name | Value |
---|---|
Molecular Formula | C34H56N2O12 |
Molecular Weight | 684.82 |
AlogP | 1.61 |
Hydrogen Bond Acceptor | 4.0 |
Hydrogen Bond Donor | 2.0 |
Number of Rotational Bond | 9.0 |
Polar Surface Area | 50.72 |
Molecular species | BASE |
Aromatic Rings | 1.0 |
Heavy Atoms | 19.0 |
Action | Mechanism of Action | Reference |
---|---|---|
ANTAGONIST | Beta-1 adrenergic receptor antagonist | DailyMed |
Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
---|---|---|---|---|---|---|
Transporter
Electrochemical transporter
SLC superfamily of solute carriers
SLC21/SLCO family of organic anion transporting polypeptides
|
- | - | - | - | 110 |
Mesh Heading | Maximum Phase | Mesh ID | Reference |
---|---|---|---|
Heart Failure | 4 | D006333 | ClinicalTrials |
Atrial Fibrillation | 3 | D001281 | ClinicalTrials |
Heart Diseases | 3 | D006331 | ClinicalTrials |
Resources | Reference |
---|---|
ChEMBL | CHEMBL2062335 |
FDA SRS | W5S57Y3A5L |
PubChem | 441308 |
SureChEMBL | SCHEMBL2051655 |