METRONIDAZOLE HYDROCHLORIDE

Search structure
Trade Names:
Synonyms:
Status: Approved (1980)
Entry Type: Small molecule
Molecule Category: Salt
UNII: 76JC1633UF
Parent Compound: METRONIDAZOLE

Structure
InChI Key FPTPAIQTXYFGJC-UHFFFAOYSA-N
Smile Cc1ncc([N+](=O)[O-])n1CCO.Cl
InChI
InChI=1S/C6H9N3O3.ClH/c1-5-7-4-6(9(11)12)8(5)2-3-10;/h4,10H,2-3H2,1H3;1H

Physicochemical Descriptors

Property Name Value
Molecular Formula C6H10ClN3O3
Molecular Weight 207.62
AlogP 0.09
Hydrogen Bond Acceptor 5.0
Hydrogen Bond Donor 1.0
Number of Rotational Bond 3.0
Polar Surface Area 81.19
Molecular species NEUTRAL
Aromatic Rings 1.0
Heavy Atoms 12.0

Pharmacology

Action Mechanism of Action Reference
INHIBITOR DNA inhibitor FDA Wikipedia

Metabolites

visNetwork

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Lymphoma 2 D008223 ClinicalTrials
Infections 0 D007239 ClinicalTrials
Osteomyelitis 0 D010019 ClinicalTrials

Related Entries

Parent

Adverse Reactions

SOC By Demographic Distribution
System Organ Classification (SOC)
Relative Frequency (%)
Nervous system disorders
22.49
General disorders and administration site conditions
10.05
Infections and infestations
8.99
Gastrointestinal disorders
7.94
Psychiatric disorders
7.67
Immune system disorders
4.76
Vascular disorders
4.76
Injury, poisoning and procedural complications
4.5
Skin and subcutaneous tissue disorders
3.97
Cardiac disorders
3.17
Investigations
3.17
Eye disorders
2.91
Musculoskeletal and connective tissue disorders
2.91
Respiratory, thoracic and mediastinal disorders
2.38

Cross References

Resources Reference
ChEBI 50687
ChEMBL CHEMBL1200869
EPA CompTox DTXSID70219228
FDA SRS 76JC1633UF
PubChem 68592
SureChEMBL SCHEMBL21293782
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