Trade Names: | |
Synonyms: | |
Status: | Approved (1996) |
Entry Type: | Small molecule |
Molecule Category: | Salt Prodrug |
UNII: | 59JV96YTXV |
Parent Compound: | MIDODRINE |
InChI Key | MGCQZNBCJBRZDT-UHFFFAOYSA-N |
---|---|
Smile | |
InChI |
|
Property Name | Value |
---|---|
Molecular Formula | C12H19ClN2O4 |
Molecular Weight | 290.75 |
AlogP | -0.19 |
Hydrogen Bond Acceptor | 5.0 |
Hydrogen Bond Donor | 3.0 |
Number of Rotational Bond | 6.0 |
Polar Surface Area | 93.81 |
Molecular species | NEUTRAL |
Aromatic Rings | 1.0 |
Heavy Atoms | 18.0 |
Action | Mechanism of Action | Reference |
---|---|---|
AGONIST | Adrenergic receptor alpha-1 agonist | DailyMed |
Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
---|---|---|---|---|---|---|
Transporter
Electrochemical transporter
SLC superfamily of solute carriers
SLC21/SLCO family of organic anion transporting polypeptides
|
- | - | - | - | 102 |
Mesh Heading | Maximum Phase | Mesh ID | Reference |
---|---|---|---|
Shock, Septic | 3 | D012772 | ClinicalTrials |
Stroke | 1 | D020521 | ClinicalTrials |
Hypotension, Orthostatic | 1 | D007024 | ClinicalTrials |
Sepsis | 1 | D018805 | ClinicalTrials |
Resources | Reference |
---|---|
ChEBI | 31847 |
ChEMBL | CHEMBL1200461 |
EPA CompTox | DTXSID1047493 |
FDA SRS | 59JV96YTXV |
PubChem | 18340 |
SureChEMBL | SCHEMBL41463 |