Pharmacology

Action Mechanism of Action Reference
INHIBITOR Ig epsilon chain C region inhibitor PubMed DailyMed
Primary Target
immunoglobulin heavy constant epsilon

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Asthma 4 D001249 ClinicalTrials
Peanut Hypersensitivity 3 D021183 ClinicalTrials
Cystitis, Interstitial 3 D018856 ClinicalTrials
Rhinitis, Allergic, Seasonal 3 D006255 ClinicalTrials
Angioedema 3 D000799 ClinicalTrials
Rhinitis, Allergic, Seasonal 3 D006255 ClinicalTrials
Food Hypersensitivity 2 D005512 ClinicalTrials
Severe Acute Respiratory Syndrome 2 D045169 ClinicalTrials
Pulmonary Disease, Chronic Obstructive 2 D029424 ClinicalTrials
Eosinophilic Esophagitis 2 D057765 ClinicalTrials
Immune System Diseases 2 D007154 ClinicalTrials
Sinusitis 2 D012852 ClinicalTrials
Pemphigoid, Bullous 2 D010391 ClinicalTrials
Milk Hypersensitivity 2 D016269 ClinicalTrials
Gastroenteritis 2 D005759 ClinicalTrials
Bronchitis 2 D001991 ClinicalTrials
Nephritis, Interstitial 2 D009395 ClinicalTrials
Hypersensitivity 2 D006967 ClinicalTrials
Lupus Erythematosus, Systemic 1 D008180 ClinicalTrials
Dermatitis, Atopic 1 D003876 ClinicalTrials
Drug Hypersensitivity 1 D004342 ClinicalTrials
Colonic Neoplasms 1 D003110 ClinicalTrials
Job Syndrome 1 D007589 ClinicalTrials

Adverse Reactions

System Organ Classification (SOC)
Relative Frequency (%)
Respiratory, thoracic and mediastinal disorders
24.07
General disorders and administration site conditions
10.72
Investigations
9.58
Infections and infestations
8.81
Nervous system disorders
5.87
Cardiac disorders
5.0
Immune system disorders
4.91
Injury, poisoning and procedural complications
4.79
Musculoskeletal and connective tissue disorders
4.75
Gastrointestinal disorders
4.47
Skin and subcutaneous tissue disorders
4.43
Vascular disorders
3.67
Psychiatric disorders
3.55

Cross References

Resources Reference
CAS NUMBER 242138-07-4
ChEMBL CHEMBL1201589
FDA SRS 2P471X1Z11
Guide to Pharmacology 6890