OMEGA-3-ACID ETHYL ESTERS

Search structure
Trade Names:
Synonyms:
K85
Status: Approved (2004)
Entry Type: Small molecule
Molecule Category: UNKNOWN Prodrug
UNII: D87YGH4Z0Q

Structure
InChI Key DTMGIJFHGGCSLO-FIAQIACWSA-N
Smile CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCC(=O)OCC.CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)OCC
InChI
InChI=1S/C24H36O2.C22H34O2/c1-3-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24(25)26-4-2;1-3-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22(23)24-4-2/h5-6,8-9,11-12,14-15,17-18,20-21H,3-4,7,10,13,16,19,22-23H2,1-2H3;5-6,8-9,11-12,14-15,17-18H,3-4,7,10,13,16,19-21H2,1-2H3/b6-5-,9-8-,12-11-,15-14-,18-17-,21-20-;6-5-,9-8-,12-11-,15-14-,18-17-

Physicochemical Descriptors

Property Name Value
Molecular Formula C46H70O4
Molecular Weight 687.06
AlogP None
Hydrogen Bond Acceptor None
Hydrogen Bond Donor None
Number of Rotational Bond None
Polar Surface Area None
Molecular species None
Aromatic Rings None
Heavy Atoms None

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Diabetes Mellitus 4 D003920 ClinicalTrials
Diabetes Mellitus, Type 2 4 D003924 ClinicalTrials
Non-alcoholic Fatty Liver Disease 3 D065626 ClinicalTrials
Hypercholesterolemia 3 D006937 ClinicalTrials
Hypertriglyceridemia 3 D015228 ClinicalTrials
Atrial Fibrillation 3 D001281 ClinicalTrials
Myocardial Infarction 3 D009203 ClinicalTrials
Heart Failure 3 D006333 ClinicalTrials
Insulin Resistance 3 D007333 ClinicalTrials
Acne Vulgaris 3 D000152 ClinicalTrials
Peripheral Arterial Disease 3 D058729 ClinicalTrials
Hyperlipoproteinemia Type II 3 D006938 ClinicalTrials
Pyelonephritis 3 D011704 ClinicalTrials
Intermittent Claudication 3 D007383 ClinicalTrials
Attention Deficit Disorder with Hyperactivity 3 D001289 ClinicalTrials
Language Disorders 3 D007806 ClinicalTrials
Dry Eye Syndromes 3 D015352 ClinicalTrials
Myocardial Ischemia 3 D017202 ClinicalTrials
Lipid Metabolism Disorders 3 D052439 ClinicalTrials
Hyperlipidemia, Familial Combined 3 D006950 ClinicalTrials
HIV Infections 3 D015658 ClinicalTrials
Hypertension 3 D006973 ClinicalTrials
Heart Diseases 3 D006331 ClinicalTrials
Alzheimer Disease 3 D000544 ClinicalTrials
Child Development Disorders, Pervasive 2 D002659 ClinicalTrials
Bipolar Disorder 2 D001714 ClinicalTrials
Depressive Disorder 2 D003866 ClinicalTrials
Glomerulonephritis, IGA 2 D005922 ClinicalTrials
Psychotic Disorders 2 D011618 ClinicalTrials
Schizophrenia 2 D012559 ClinicalTrials
Diabetes Mellitus, Type 1 2 D003922 ClinicalTrials
Autistic Disorder 2 D001321 ClinicalTrials
Lichen Planus, Oral 2 D017676 ClinicalTrials
Renal Insufficiency, Chronic 2 D051436 ClinicalTrials
Periodontitis 2 D010518 ClinicalTrials
Dysthymic Disorder 2 D019263 ClinicalTrials
Myositis 2 D009220 ClinicalTrials
Cognitive Dysfunction 2 D060825 ClinicalTrials
Inflammation 2 D007249 ClinicalTrials
Epilepsy 2 D004827 ClinicalTrials
Sarcopenia 2 D055948 ClinicalTrials
Precursor Cell Lymphoblastic Leukemia-Lymphoma 2 D054198 ClinicalTrials
Aggression 2 D000374 ClinicalTrials
Depression, Postpartum 2 D019052 ClinicalTrials
Oral Ulcer 2 D019226 ClinicalTrials
Depressive Disorder, Major 2 D003865 ClinicalTrials
Breast Neoplasms 2 D001943 ClinicalTrials
Wounds and Injuries 1 D014947 ClinicalTrials
Carcinoma, Squamous Cell 1 D002294 ClinicalTrials
Carcinoma, Non-Small-Cell Lung 1 D002289 ClinicalTrials
Pancreatic Neoplasms 1 D010190 ClinicalTrials
Lymphoma, Non-Hodgkin 1 D008228 ClinicalTrials
Carcinoma, Merkel Cell 1 D015266 ClinicalTrials
Colorectal Neoplasms 1 D015179 ClinicalTrials
Fatty Liver 1 D005234 ClinicalTrials
Breast Carcinoma In Situ 1 D000071960 ClinicalTrials
Urinary Bladder Neoplasms 1 D001749 ClinicalTrials
Melanoma 1 D008545 ClinicalTrials
Ovarian Neoplasms 1 D010051 ClinicalTrials
Chagas Cardiomyopathy 0 D002598 ClinicalTrials
Metabolic Syndrome 0 D024821 ClinicalTrials

Related Entries

MCS

Side Effects from Label

Adverse Reactions

SOC By Demographic Distribution
System Organ Classification (SOC)
Relative Frequency (%)
Gastrointestinal disorders
15.53
General disorders and administration site conditions
12.43
Nervous system disorders
7.02
Product issues
6.67
Injury, poisoning and procedural complications
6.49
Vascular disorders
6.2
Cardiac disorders
5.63
Investigations
5.62
Respiratory, thoracic and mediastinal disorders
5.3
Musculoskeletal and connective tissue disorders
4.16
Skin and subcutaneous tissue disorders
3.73
Surgical and medical procedures
3.69
Psychiatric disorders
2.75
Infections and infestations
2.25
Metabolism and nutrition disorders
2.09

Cross References

Resources Reference
CAS NUMBER 308081-97-2
ChEMBL CHEMBL1200711
FDA SRS D87YGH4Z0Q
PubChem 9831414
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