PANTOPRAZOLE SODIUM

Search structure
Trade Names:
Synonyms:
Status: Approved (2000)
Entry Type: Small molecule
Molecule Category: Salt
UNII: 6871619Q5X
Parent Compound: PANTOPRAZOLE

Structure
InChI Key YNWDKZIIWCEDEE-UHFFFAOYSA-N
Smile COc1ccnc(C[S+]([O-])c2nc3cc(OC(F)F)ccc3[n-]2)c1OC.[Na+]
InChI
InChI=1S/C16H14F2N3O4S.Na/c1-23-13-5-6-19-12(14(13)24-2)8-26(22)16-20-10-4-3-9(25-15(17)18)7-11(10)21-16;/h3-7,15H,8H2,1-2H3;/q-1;+1

Physicochemical Descriptors

Property Name Value
Molecular Formula C16H16F2N3NaO5S
Molecular Weight 423.37
AlogP 2.88
Hydrogen Bond Acceptor 6.0
Hydrogen Bond Donor 1.0
Number of Rotational Bond 7.0
Polar Surface Area 86.33
Molecular species NEUTRAL
Aromatic Rings 3.0
Heavy Atoms 26.0

Pharmacology

Action Mechanism of Action Reference
INHIBITOR Potassium-transporting ATPase inhibitor PubMed PubMed DailyMed

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Gastroesophageal Reflux 4 D005764 ClinicalTrials
Neoplasms 1 D009369 ClinicalTrials
Lecithin Cholesterol Acyltransferase Deficiency 1 D007863 ClinicalTrials

Related Entries

Scaffolds

Parent

Adverse Reactions

SOC By Demographic Distribution
System Organ Classification (SOC)
Relative Frequency (%)
Renal and urinary disorders
30.43
General disorders and administration site conditions
9.15
Gastrointestinal disorders
8.64
Injury, poisoning and procedural complications
5.31
Nervous system disorders
5.08
Vascular disorders
4.3
Skin and subcutaneous tissue disorders
3.91
Respiratory, thoracic and mediastinal disorders
3.88
Investigations
3.45
Cardiac disorders
3.42
Musculoskeletal and connective tissue disorders
3.38
Metabolism and nutrition disorders
3.25
Psychiatric disorders
3.17
Immune system disorders
2.93
Infections and infestations
2.4

Cross References

Resources Reference
ChEMBL CHEMBL3989559
FDA SRS 6871619Q5X
PubChem 11954257
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