Pharmacology

Action Mechanism of Action Reference
ANTAGONIST Growth hormone receptor antagonist DailyMed
Primary Target
Growth hormone receptor

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Pituitary Diseases 3 D010900 ClinicalTrials
Fibrous Dysplasia, Polyostotic 3 D005359 ClinicalTrials
Sarcoma 1 D012509 ClinicalTrials
Colorectal Neoplasms 1 D015179 ClinicalTrials
Breast Neoplasms 1 D001943 ClinicalTrials
Lung Neoplasms 1 D008175 ClinicalTrials
Prostatic Neoplasms 1 D011471 ClinicalTrials

Adverse Reactions

System Organ Classification (SOC)
Relative Frequency (%)
General disorders and administration site conditions
17.09
Injury, poisoning and procedural complications
13.74
Investigations
12.34
Nervous system disorders
7.87
Gastrointestinal disorders
6.1
Musculoskeletal and connective tissue disorders
5.77
Skin and subcutaneous tissue disorders
5.21
Vascular disorders
4.56
Metabolism and nutrition disorders
2.92
Cardiac disorders
2.86
Respiratory, thoracic and mediastinal disorders
2.81
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
2.74
Endocrine disorders
2.65
Psychiatric disorders
2.56
Eye disorders
2.45
Infections and infestations
2.35

Cross References

Resources Reference
CAS NUMBER 218620-50-9
ChEMBL CHEMBL1201515
FDA SRS N824AOU5XV
Guide to Pharmacology 7485