PENICILLIN G POTASSIUM

Search structure
Trade Names:
Synonyms:
Status: Approved (1947)
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: VL775ZTH4C

Structure
InChI Key IYNDLOXRXUOGIU-LQDWTQKMSA-M
Smile CC1(C)S[C@@H]2[C@H](NC(=O)Cc3ccccc3)C(=O)N2[C@H]1C(=O)[O-].[K+]
InChI
InChI=1S/C16H18N2O4S.K/c1-16(2)12(15(21)22)18-13(20)11(14(18)23-16)17-10(19)8-9-6-4-3-5-7-9;/h3-7,11-12,14H,8H2,1-2H3,(H,17,19)(H,21,22);/q;+1/p-1/t11-,12+,14-;/m1./s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C16H17KN2O4S
Molecular Weight 372.49
AlogP 0.86
Hydrogen Bond Acceptor 4.0
Hydrogen Bond Donor 2.0
Number of Rotational Bond 4.0
Polar Surface Area 86.71
Molecular species ACID
Aromatic Rings 1.0
Heavy Atoms 23.0

Pharmacology

Action Mechanism of Action Reference
INHIBITOR Bacterial penicillin-binding protein inhibitor PubMed PubMed PubMed

Metabolites

visNetwork

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Infections 3 D007239 ClinicalTrials
Pneumococcal Infections 3 D011008 ClinicalTrials
Bacteremia 3 D016470 ClinicalTrials
Tonsillitis 3 D014069 ClinicalTrials
Pharyngitis 3 D010612 ClinicalTrials
Pneumonia 3 D011014 ClinicalTrials
Neoplasms 1 D009369 ClinicalTrials
Carcinoma, Squamous Cell 1 D002294 ClinicalTrials
Neoplasms 1 D009369 ClinicalTrials
Stomach Neoplasms 1 D013274 ClinicalTrials
Osteomyelitis 0 D010019 ClinicalTrials

Related Entries

MCS

Scaffolds

Adverse Reactions

SOC By Demographic Distribution
System Organ Classification (SOC)
Relative Frequency (%)
Immune system disorders
58.85
Skin and subcutaneous tissue disorders
11.92
General disorders and administration site conditions
6.41
Injury, poisoning and procedural complications
4.32
Vascular disorders
3.74
Gastrointestinal disorders
2.38
Nervous system disorders
2.07

Cross References

Resources Reference
ChEBI 7963
ChEMBL CHEMBL1223
EPA CompTox DTXSID7045106
FDA SRS VL775ZTH4C
PubChem 23664709
SureChEMBL SCHEMBL34078
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