Trade Names: | |
Synonyms: | |
Status: | Approved (1993) |
Entry Type: | Small molecule |
Molecule Category: | Salt Prodrug |
UNII: | 1964X464OJ |
Parent Compound: | PERINDOPRIL |
InChI Key | IYNMDWMQHSMDDE-MHXJNQAMSA-N |
---|---|
Smile | |
InChI |
|
Property Name | Value |
---|---|
Molecular Formula | C23H43N3O5 |
Molecular Weight | 441.61 |
AlogP | 1.94 |
Hydrogen Bond Acceptor | 5.0 |
Hydrogen Bond Donor | 2.0 |
Number of Rotational Bond | 8.0 |
Polar Surface Area | 95.94 |
Molecular species | ACID |
Aromatic Rings | 0.0 |
Heavy Atoms | 26.0 |
Action | Mechanism of Action | Reference |
---|---|---|
INHIBITOR | Angiotensin-converting enzyme inhibitor | FDA |
Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
---|---|---|---|---|---|---|
Transporter
Electrochemical transporter
SLC superfamily of solute carriers
SLC21/SLCO family of organic anion transporting polypeptides
|
- | - | - | - | 108 |
Mesh Heading | Maximum Phase | Mesh ID | Reference |
---|---|---|---|
Essential Hypertension | 3 | D000075222 | ClinicalTrials |
Resources | Reference |
---|---|
ChEBI | 8025 |
ChEMBL | CHEMBL1200343 |
EPA CompTox | DTXSID1044198 |
FDA SRS | 1964X464OJ |
KEGG | C07707 |
PubChem | 441313 |
SureChEMBL | SCHEMBL41679 |