Structure

InChI Key IYNMDWMQHSMDDE-MHXJNQAMSA-N
Smile CC(C)(C)N.CCC[C@H](N[C@@H](C)C(=O)N1[C@H](C(=O)O)C[C@@H]2CCCC[C@@H]21)C(=O)OCC
InChI
InChI=1S/C19H32N2O5.C4H11N/c1-4-8-14(19(25)26-5-2)20-12(3)17(22)21-15-10-7-6-9-13(15)11-16(21)18(23)24;1-4(2,3)5/h12-16,20H,4-11H2,1-3H3,(H,23,24);5H2,1-3H3/t12-,13-,14-,15-,16-;/m0./s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C23H43N3O5
Molecular Weight 441.61
AlogP 1.94
Hydrogen Bond Acceptor 5.0
Hydrogen Bond Donor 2.0
Number of Rotational Bond 8.0
Polar Surface Area 95.94
Molecular species ACID
Aromatic Rings 0.0
Heavy Atoms 26.0

Pharmacology

Action Mechanism of Action Reference
INHIBITOR Angiotensin-converting enzyme inhibitor FDA

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Essential Hypertension 3 D000075222 ClinicalTrials

Related Entries

Parent

Adverse Reactions

System Organ Classification (SOC)
Relative Frequency (%)
General disorders and administration site conditions
9.5
Respiratory, thoracic and mediastinal disorders
8.9
Gastrointestinal disorders
8.71
Skin and subcutaneous tissue disorders
8.3
Nervous system disorders
8.27
Cardiac disorders
7.7
Vascular disorders
7.61
Immune system disorders
5.98
Metabolism and nutrition disorders
5.95
Investigations
5.71
Injury, poisoning and procedural complications
4.05
Renal and urinary disorders
3.57
Psychiatric disorders
3.14
Musculoskeletal and connective tissue disorders
3.05
Infections and infestations
2.48

Cross References

Resources Reference
ChEBI 8025
ChEMBL CHEMBL1200343
EPA CompTox DTXSID1044198
FDA SRS 1964X464OJ
KEGG C07707
PubChem 441313
SureChEMBL SCHEMBL41679