| Trade Names: | |
| Synonyms: | |
| Status: | Approved (2012) |
| Entry Type: | Antibody |
| Molecule Category: | UNKNOWN |
| ATC: | L01XC13 |
| UNII: | K16AIQ8CTM |
Pharmacology
| Action | Mechanism of Action | Reference |
|---|---|---|
| INHIBITOR | Receptor protein-tyrosine kinase erbB-2 inhibitor | DailyMed |
| Primary Target | |
|---|---|
| erb-b2 receptor tyrosine kinase 2 |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Neoplasms | 4 | D009369 | ClinicalTrials |
| Breast Neoplasms | 4 | D001943 | ClinicalTrials |
| Breast Neoplasms | 4 | D001943 | ClinicalTrials |
| Stomach Neoplasms | 3 | D013274 | ClinicalTrials |
| Ovarian Neoplasms | 3 | D010051 | ClinicalTrials |
| Inflammatory Breast Neoplasms | 3 | D058922 | ClinicalTrials |
| Colorectal Neoplasms | 2 | D015179 | ClinicalTrials |
| Carcinoma, Non-Small-Cell Lung | 2 | D002289 | ClinicalTrials |
| Pancreatic Neoplasms | 2 | D010190 | ClinicalTrials |
| Colorectal Neoplasms | 2 | D015179 | ClinicalTrials |
| Neoplasm Metastasis | 2 | D009362 | ClinicalTrials |
| Hemangiosarcoma | 2 | D006394 | ClinicalTrials |
| Peritoneal Neoplasms | 2 | D010534 | ClinicalTrials |
| Carcinoma, Neuroendocrine | 2 | D018278 | ClinicalTrials |
| Fallopian Tube Neoplasms | 2 | D005185 | ClinicalTrials |
| Prostatic Neoplasms, Castration-Resistant | 2 | D064129 | ClinicalTrials |
| Rectal Neoplasms | 1 | D012004 | ClinicalTrials |
| Breast Neoplasms, Male | 1 | D018567 | ClinicalTrials |
| Esophageal Neoplasms | 1 | D004938 | ClinicalTrials |
| Colonic Neoplasms | 1 | D003110 | ClinicalTrials |
Adverse Reactions
System Organ Classification (SOC)
Cross References
| Resources | Reference |
|---|---|
| CAS NUMBER | 380610-27-5 |
| ChEMBL | CHEMBL2007641 |
| FDA SRS | K16AIQ8CTM |
| Guide to Pharmacology | 5046 |
CONTENTS