Trade Names: | |
Synonyms: | |
Status: | Approved (1952) |
Entry Type: | Small molecule |
Molecule Category: | Salt |
UNII: | 04JA59TNSJ |
Parent Compound: | PHENYLEPHRINE |
InChI Key | OCYSGIYOVXAGKQ-FVGYRXGTSA-N |
---|---|
Smile | |
InChI |
|
Property Name | Value |
---|---|
Molecular Formula | C9H14ClNO2 |
Molecular Weight | 203.67 |
AlogP | 0.65 |
Hydrogen Bond Acceptor | 3.0 |
Hydrogen Bond Donor | 3.0 |
Number of Rotational Bond | 3.0 |
Polar Surface Area | 52.49 |
Molecular species | BASE |
Aromatic Rings | 1.0 |
Heavy Atoms | 12.0 |
Action | Mechanism of Action | Reference |
---|---|---|
AGONIST | Adrenergic receptor alpha-1 agonist | ISBN |
Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
---|---|---|---|---|---|---|
Transporter
Electrochemical transporter
SLC superfamily of solute carriers
SLC21/SLCO family of organic anion transporting polypeptides
|
- | - | - | - | 106 |
Mesh Heading | Maximum Phase | Mesh ID | Reference |
---|---|---|---|
Common Cold | 4 | D003139 | ClinicalTrials |
Cataract | 3 | D002386 | ClinicalTrials |
Rhinitis, Vasomotor | 3 | D012223 | ClinicalTrials |
Respiratory Tract Infections | 3 | D012141 | ClinicalTrials |
Acute Lung Injury | 2 | D055371 | ClinicalTrials |
Stomach Neoplasms | 2 | D013274 | ClinicalTrials |
Infections | 1 | D007239 | ClinicalTrials |
Rhinitis | 1 | D012220 | ClinicalTrials |
Cardiovascular Diseases | 1 | D002318 | ClinicalTrials |
Arrhythmias, Cardiac | 1 | D001145 | ClinicalTrials |
Resources | Reference |
---|---|
ChEBI | 8094 |
ChEMBL | CHEMBL1200339 |
EPA CompTox | DTXSID3021142 |
FDA SRS | 04JA59TNSJ |
PubChem | 441279 |
SureChEMBL | SCHEMBL24654 |